Patents by Inventor Tatsumi Ito

Tatsumi Ito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11229907
    Abstract: A microchip is provided, which includes a substrate including a fluid channel structure. The fluid channel structure includes a first fluid introduction channel and a second fluid introduction channel configured to meet so as to allow merging of a first fluid introduced from the first fluid introduction channel and a second fluid introduced from the second fluid introduction channel. A tapered portion is configured to be positioned after merging the first fluid and the second fluid so as to suppress a spiral flow field generated after the merging.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: January 25, 2022
    Assignee: Sony Corporation
    Inventors: Tatsumi Ito, Shoji Akiyama, Masaya Kakuta, Takeshi Yamasaki
  • Publication number: 20210402440
    Abstract: There is provided a microparticle sorting method including a procedure of collecting a microparticle in a fluid that flows through a main channel in a branch channel that is in communication with the main channel by generating a negative pressure in the branch channel. In the procedure, a flow of a fluid is formed that flows toward a side of the main channel from a side of the branch channel at a communication opening between the main channel and the branch channel.
    Type: Application
    Filed: September 8, 2021
    Publication date: December 30, 2021
    Inventor: TATSUMI ITO
  • Patent number: 11169074
    Abstract: In the present technology, the timing at which suction is performed is optimized in order to enhance the microparticle separation performance in a technology for separating target microparticles in a microchip. For this purpose, the present technology provides a method of optimizing a microparticle suction condition, and the like, using a microchip having a main flow channel through which a liquid containing a microparticle flows, a microparticle suction flow channel arranged coaxially with the main flow channel, and a branch flow channel branching from the main flow channel. The method includes: a branch point specifying process of specifying a branch point at which the branch flow channel branches from the main flow channel; and a time assignment process of assigning a time T1 to be applied to suction of the microparticle.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: November 9, 2021
    Assignee: SONY CORPORATION
    Inventors: Gakuji Hashimoto, Tatsumi Ito, Kazuya Takahashi, Junji Kajihara
  • Publication number: 20210331172
    Abstract: Provided is a technology for preparing a mixture including multiple types of microparticles in accordance with a predetermined ratio. The present technology provides a microparticle sorting device (100) including a control unit (103) comprising a determination unit that determines whether microparticles are sorted, on the basis of light generated by irradiating, with light, the microparticles flowing through a flow channel (155), in which the determination unit performs a primary sorting determination to determine, on the basis of characteristics of the light generated, whether the microparticles belong to any one of two or more different microparticle populations, and then performs a secondary sorting determination to determine whether the microparticles determined to belong to any one of the microparticle populations in the primary sorting determination are sorted, on the basis of the particle constituent ratio specified for the two or more different microparticle populations.
    Type: Application
    Filed: September 10, 2019
    Publication date: October 28, 2021
    Applicant: Sony Corporation
    Inventors: Tatsumi Ito, Gakuji Hashimoto, Kazuya Takahashi, Hirotaka Yoshida, Yasunobu Kato
  • Patent number: 11148173
    Abstract: There is provided a microparticle sorting method including a procedure of collecting a microparticle in a fluid that flows through a main channel in a branch channel that is in communication with the main channel by generating a negative pressure in the branch channel. In the procedure, a flow of a fluid is formed that flows toward a side of the main channel from a side of the branch channel at a communication opening between the main channel and the branch channel.
    Type: Grant
    Filed: January 3, 2020
    Date of Patent: October 19, 2021
    Assignee: SONY CORPORATION
    Inventor: Tatsumi Ito
  • Publication number: 20210245202
    Abstract: A particle sorting apparatus is provided. The particle sorting apparatus includes a first detector of a first scatter channel to detect a first light scatter generated by a particle flowing in a flow channel of a fluid sample and passing through a first laser beam, and a second detector of a second scatter channel to detect a second light scatter generated by the particle flowing in the flow channel of the fluid sample and passing through a second laser beam. The particle sorting apparatus also includes circuitry configured to output a first scatter pulse information and a first detection time of the first light scatter channel, a second scatter pulse information and a second detection time of the second light scatter channel. The first laser beam and the second laser beam are irradiated to the particle in different positions of the flow channel.
    Type: Application
    Filed: April 26, 2021
    Publication date: August 12, 2021
    Inventor: Tatsumi ITO
  • Patent number: 11072002
    Abstract: A particle sorting apparatus is provided. The particle sorting apparatus includes a first light irradiating unit including a first mirror and a first light source for irradiating a first light to particles flowing through a flow path at a first position; a second light irradiating unit including a second mirror and a second light source configured to irradiate a second light to particles flowing through the flow path at a second position which is different from the first position; a light detecting unit is configured to detect a light emitted from the particles; a sorting unit; and a sorting control unit configured to control sorting of the particles based on data of the particles detected at the light detecting unit and an arrival time associated with a time difference between a light from the first light irradiating unit and a light from the second light irradiating unit; wherein the flow path and the sorting unit are provided within a microchip.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: July 27, 2021
    Assignee: Sony Corporation
    Inventor: Tatsumi Ito
  • Publication number: 20210170402
    Abstract: A microparticle sorting microchip for a flow cytometer is provided to enable sorting of microparticles at higher speed, higher purity, and higher acquisition rate. The microparticle sorting microchip includes a main channel through which a microparticle-containing fluid flows, a trap channel coaxially communicating with the main channel, a trap chamber communicating with the trap channel, and a gate channel intersecting the trap channel. The trap channel has an opening intersecting the gate channel. The trap channel has a smaller cross-sectional area upstream of the opening than downstream of the opening along a direction in which the microparticle-containing fluid flows.
    Type: Application
    Filed: November 9, 2018
    Publication date: June 10, 2021
    Applicant: Sony Corporation
    Inventors: Tatsumi Ito, Kazuya Takahashi, Masahiro Matsumoto
  • Publication number: 20210001338
    Abstract: A method of extracting microparticles by detecting target microparticles for extraction in a main flow path which communicates with a pressure chamber, generating for each of the detected target microparticles a change in a negative pressure in the pressure chamber communicating with the main flow path to separate and extract each of the detected target microparticles flowing in the main flow path into the pressure chamber, wherein generating the change of the negative pressure to extract the detected target microparticles comprises generating a negative change in pressure by a different amount in accordance with a separation between the detected target microparticles.
    Type: Application
    Filed: January 7, 2019
    Publication date: January 7, 2021
    Applicant: Sony Corporation
    Inventors: Kazuya Takahashi, Tatsumi Ito, Yoichi Katsumoto
  • Publication number: 20200338550
    Abstract: A microchip is provided, which includes a substrate including a fluid channel structure. The fluid channel structure includes a first fluid introduction channel and a second fluid introduction channel configured to meet so as to allow merging of a first fluid introduced from the first fluid introduction channel and a second fluid introduced from the second fluid introduction channel. A tapered portion is configured to be positioned after merging the first fluid and the second fluid so as to suppress a spiral flow field generated after the merging.
    Type: Application
    Filed: July 13, 2020
    Publication date: October 29, 2020
    Inventors: Tatsumi ITO, Shoji AKIYAMA, Masaya KAKUTA, Takeshi YAMASAKI
  • Patent number: 10744501
    Abstract: A microchip is provided, which includes a substrate including a fluid channel structure. The fluid channel structure includes a first fluid introduction channel and a second fluid introduction channel configured to meet so as to allow merging of a first fluid introduced from the first fluid introduction channel and a second fluid introduced from the second fluid introduction channel. A tapered portion is configured to be positioned after merging the first fluid and the second fluid so as to suppress a spiral flow field generated after the merging.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: August 18, 2020
    Assignee: Sony Corporation
    Inventors: Tatsumi Ito, Shoji Akiyama, Masaya Kakuta, Takeshi Yamasaki
  • Publication number: 20200139408
    Abstract: There is provided a microparticle sorting method including a procedure of collecting a microparticle in a fluid that flows through a main channel in a branch channel that is in communication with the main channel by generating a negative pressure in the branch channel. In the procedure, a flow of a fluid is formed that flows toward a side of the main channel from a side of the branch channel at a communication opening between the main channel and the branch channel.
    Type: Application
    Filed: January 3, 2020
    Publication date: May 7, 2020
    Inventor: TATSUMI ITO
  • Publication number: 20200124517
    Abstract: In the present technology, the timing at which suction is performed is optimized in order to enhance the microparticle separation performance in a technology for separating target microparticles in a microchip. For this purpose, the present technology provides a method of optimizing a microparticle suction condition, and the like, using a microchip having a main flow channel through which a liquid containing a microparticle flows, a microparticle suction flow channel arranged coaxially with the main flow channel, and a branch flow channel branching from the main flow channel.
    Type: Application
    Filed: February 20, 2018
    Publication date: April 23, 2020
    Inventors: GAKUJI HASHIMOTO, TATSUMI ITO, KAZUYA TAKAHASHI, JUNJI KAJIHARA
  • Publication number: 20200072732
    Abstract: To provide a technology of optimizing a suction condition of a microparticle. The present technology provides an optimizing method of a suction condition of a microparticle including: a particle number counting step of detecting a time point when a microparticle passes through a predetermined position on a main flow path through which liquid containing the microparticle flows, sucking the microparticle from the main flow path to a microparticle suction flow path by the microparticle suction flow path with a predetermined suction force, and counting the number of microparticles sucked into the microparticle suction flow path; and a step of determining an elapsed time from passage through the predetermined position with which the suction by the microparticle suction flow path should be performed on the basis of a time from the time point when the microparticle passes through the predetermined position on the main flow path until the suction is performed and the number of counted microparticles.
    Type: Application
    Filed: February 14, 2018
    Publication date: March 5, 2020
    Applicant: Sony Corporation
    Inventors: Gakuji Hashimoto, Tatsumi Ito, Kazuya Takahashi, Junji Kajihara
  • Patent number: 10562074
    Abstract: There is provided a microparticle sorting method including a procedure of collecting a microparticle in a fluid that flows through a main channel in a branch channel that is in communication with the main channel by generating a negative pressure in the branch channel. In the procedure, a flow of a fluid is formed that flows toward a side of the main channel from a side of the branch channel at a communication opening between the main channel and the branch channel.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: February 18, 2020
    Assignee: SONY CORPORATION
    Inventor: Tatsumi Ito
  • Publication number: 20200011782
    Abstract: The present technology is directed to providing a new technology to form a stable flow inside a flow channel. The present technology provides a flow channel unit including a flow rate fluctuation suppressing unit, in which a cross-sectional area of at least part of a downstream flow channel of the flow rate fluctuation suppressing unit is smaller than a cross-sectional area of a remaining part of the flow channel. Furthermore, the present technology also provides a microparticle analysis device including the flow channel unit that includes the flow rate fluctuation suppressing unit, in which the cross-sectional area of at least part of a downstream flow channel of the flow rate fluctuation suppressing unit is smaller than the cross-sectional area of a remaining part of the flow channel.
    Type: Application
    Filed: December 26, 2017
    Publication date: January 9, 2020
    Inventors: SHINJI TASHIRO, TATSUMI ITO
  • Publication number: 20200001328
    Abstract: A particle sorting apparatus is provided. The particle sorting apparatus includes a first light irradiating unit including a first mirror and a first light source for irradiating a first light to particles flowing through a flow path at a first position; a second light irradiating unit including a second mirror and a second light source configured to irradiate a second light to particles flowing through the flow path at a second position which is different from the first position; a light detecting unit is configured to detect a light emitted from the particles; a sorting unit; and a sorting control unit configured to control sorting of the particles based on data of the particles detected at the light detecting unit and an arrival time associated with a time difference between a light from the first light irradiating unit and a light from the second light irradiating unit; wherein the flow path and the sorting unit are provided within a microchip.
    Type: Application
    Filed: August 16, 2019
    Publication date: January 2, 2020
    Inventor: Tatsumi ITO
  • Publication number: 20190366343
    Abstract: There is provided a microchip comprising: a main flow path through which a liquid containing micro articles flows; and a branch flow path that branches from the main flow path. A cross-sectional area of a portion of the main flow path is substantially constant up to a branch start position or decreases toward the branch start position, and a radius of curvature R of a side wall that connects a side wall of the main flow path and a side wall of the branch flow path is 0.5 mm or less and more than 0 mm.
    Type: Application
    Filed: February 15, 2018
    Publication date: December 5, 2019
    Applicant: Sony Corporation
    Inventors: Kazuya Takahashi, Tatsumi Ito, Yoichi Katsumoto
  • Patent number: D869308
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: December 10, 2019
    Assignee: SONY CORPORATION
    Inventors: Yuji Akiyama, Shoji Akiyama, Gakuji Hashimoto, Hiroto Kasai, Masaya Kakuta, Takeshi Yamasaki, Tatsumi Ito, Masataka Shinoda
  • Patent number: D907242
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: January 5, 2021
    Assignee: SONY CORPORATION
    Inventors: Masataka Shinoda, Shoji Akiyama, Masaya Kakuta, Takeshi Yamasaki, Tatsumi Ito, Yuji Akiyama, Gakuji Hashimoto, Hiroto Kasai