Patents by Inventor Tatsuo Sugioka

Tatsuo Sugioka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5767146
    Abstract: An anti-osteopathic composition comprising as an active ingredient a compound represented by the following formula (I), (II) or (Ill): ##STR1## which is useful for therapeutic and prophylactic treatment of osteopathia such as osteoporosis and bone fracture.
    Type: Grant
    Filed: September 22, 1997
    Date of Patent: June 16, 1998
    Assignees: Hoechst Japan Limited, Koichi Shudo
    Inventors: Koichi Shudo, Tatsuo Sugioka, Mizuho Inazu, Hideyuki Tanaka, Tsutomu Inoue, Kazuyuki Kitamura
  • Patent number: 5716995
    Abstract: An anti-osteopathic composition comprising as an active ingredient a compound represented by the following formula (I), (II) or (III): ##STR1## which is useful for therapeutic and prophylactic treatment of osteopathia such as osteoporosis and bone fracture.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 10, 1998
    Assignees: Hoechst Japan Limited, Koichi Shudo
    Inventors: Koichi Shudo, Tatsuo Sugioka, Mizuho Inazu, Hideyuki Tanaka, Tsutomu Inoue, Kazuyuki Kitamura
  • Patent number: 5703128
    Abstract: An anti-osteopathic composition comprising as an active ingredient a compound represented by the following formula (I), (II) or (III): ##STR1## which is useful for therapeutic and prophylactic treatment of osteopathia such as osteoporosis and bone fracture.
    Type: Grant
    Filed: March 8, 1996
    Date of Patent: December 30, 1997
    Assignees: Hoechst Japan Limited, Koichi Shudo
    Inventors: Koichi Shudo, Tatsuo Sugioka, Mizuho Inazu, Hideyuki Tanaka, Tsutomu Inoue, Kazuyuki Kitamura
  • Patent number: 5525618
    Abstract: Treatment of osteopathic comprising administering as an active ingredient a compound represented by the following formula (I), (II) or (III): ##STR1##
    Type: Grant
    Filed: April 1, 1994
    Date of Patent: June 11, 1996
    Assignee: Hoechst Japan Limited
    Inventors: Koichi Shudo, Tatsuo Sugioka, Mizuho Inazu, Hideyuki Tanaka, Tsutomu Inoue, Kazuyuki Kitamura
  • Patent number: 5428181
    Abstract: A compound represented by the general formula: ##STR1## wherein A-O-denotes a residue of a compound having an estrogenic activity; R.sub.1 denotes H or a C.sub.1 -C.sub.6 alkyl group; X denotes a single bond, a C.sub.1 -C.sub.10 alkylene group or a group of the formula ##STR2## wherein R.sub.2 denotes H or a C.sub.1 -C.sub.5 alkyl group; Z denotes a nitro group or a halogen; n is an integer of 3 to 12; k is an integer of 1 to 5; L is an integer of 0 to 5; and q is an integer of 1 to 3,and physiologically acceptable salts thereof are disclosed.The compounds have a high affinity to bone tissues, and the compounds per se and metabolites thereof show significant therapeutic effect on bone diseases such as osteoporosis, rheumatoid arthritis and osteoarthritis.
    Type: Grant
    Filed: December 24, 1992
    Date of Patent: June 27, 1995
    Assignee: Hoechst Japan Limited
    Inventors: Tatsuo Sugioka, Mizuho Inazu
  • Patent number: 5245052
    Abstract: A process for the manufacture of a 6-acyl-7-deacetylforskolin derivative represented by formula (I) ##STR1## by reacting a 7-acyl-7-deacetylforskolin derivative represented by formula (II) ##STR2## with a strong base in an aprotic solvent.
    Type: Grant
    Filed: July 19, 1991
    Date of Patent: September 14, 1993
    Assignees: Nippon Kayaku Co. Ltd., Hoechst Japan Limited
    Inventors: Tochiro Tatee, Tatsuo Sugioka