Patents by Inventor Tetsuya Yamagata

Tetsuya Yamagata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190376088
    Abstract: The present invention provides a method of treating a disease associated with elevated KRAS activity or expression in a subject, comprising suppressing KRAS expression in the subject by targeting an expression regulatory region of KRAS gene using a CRISPR-Guide Nucleotide Directed Modulation (GNDM). Also, provided is a CRISPR-GNDM system for suppressing KRAS expression comprising (a) a protein selected from the group consisting of dCas9 or dCpf1, a fusion protein of dCas9 or dCpf1 and Kruppel associated box (KRAB), and (b) a guide nucleotide targeting an expression regulatory region of KRAS gene.
    Type: Application
    Filed: February 7, 2018
    Publication date: December 12, 2019
    Applicant: EdiGENE Corporation
    Inventors: Tetsuya YAMAGATA, Yuanbo QIN, Haruhiko MORITA, Talha AKBULUT, lain Robert THOMPSON
  • Publication number: 20130149503
    Abstract: The present invention provides an intermediate film for laminated glass which allows, in a laminated glass, improvement in penetration resistance throughout the laminated glass, and a laminated glass including the intermediate film for laminated glass. In an intermediate film for laminated glass, a first end is thinner than a second end, and in the intermediate film for laminated glass, a thin region has a moisture content higher than a moisture content of the thick region; and a laminated glass includes a first component for laminated glass, a second component for laminated glass, and an intermediate film sandwiched between the first component for laminated glass and the second component for laminated glass.
    Type: Application
    Filed: September 1, 2011
    Publication date: June 13, 2013
    Inventors: Satoru Yamamoto, Takeshi Yoshida, Daishun Fukui, Tetsuya Yamagata
  • Patent number: 6974620
    Abstract: A polyester film for use in a capacitor having high heat resistance, which consists of a biaxially oriented film containing a polyester (A) as a main component and a polyimide (B) and has a glass transition temperature of 105° C. to 145° C. and an elongation at break in the machine direction of 70% to 150%, offers a high glass transition temperature and excellent insulation volume resistance and insulation breakdown voltage at high ambient temperatures. This film can produce a metallized film for use in a capacitor having high heat resistance and also a film capacitor having high heat resistance.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: December 13, 2005
    Assignee: Toray Industries, Inc.
    Inventors: Tetsuya Tsunekawa, Masayoshi Asakura, Tetsuya Yamagata
  • Patent number: 4455146
    Abstract: A novel plaster comprising a thermoplastic elastomer, an oil or higher fatty acid, a tack-providing resin and a medicinal ingredient. The plaster may be easily released therefrom without giving appreciable irritation or pain to the skin and body hairs of human bodies after applied thereto, while it may nevertheless exhibit satisfactory tackiness and adhesive strength when applied to human bodies.
    Type: Grant
    Filed: March 2, 1982
    Date of Patent: June 19, 1984
    Assignee: Hisamitsu Pharmaceutical Co., Ltd.
    Inventors: Kanji Noda, Akira Nakagawa, Tetsuya Yamagata, Masasi Kobayasi, Tadayoshi Suenaga, Fumiaki Tokubuchi, Kazuki Noguchi, Tadaaki Yoshitake, Masayoshi Tsuji, Hiroyuki Ide
  • Patent number: 4393076
    Abstract: An anti-inflammatory analgesic gel composition comprising (1) ketoprofen and/or flurbiprofen as the effective ingredient, as well as (2) a glycol, lower alcohol, water and/or a mixture of a lower alcohol with water, (3) a gel-forming agent and, if desired, (4) a solubilizing agent and/or non-ionic surface-active agent as the ingredients of a gel base for the gel composition.
    Type: Grant
    Filed: February 16, 1982
    Date of Patent: July 12, 1983
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kanji Noda, Akira Nakagawa, Tetsuya Yamagata, Hiroyuki Ide
  • Patent number: 4205685
    Abstract: A thermogenic sheet combined poultice comprising a thermogenic composition layer capable of generating heat in the presence of air or oxygen and a heat-stable wet pack composition layer; and a process for the production of the thermogenic sheet combined poultice.
    Type: Grant
    Filed: October 4, 1977
    Date of Patent: June 3, 1980
    Assignees: Hisamitsu Pharmaceutical Co., Ltd., Toyo Ink Manufacturing Co., Ltd.
    Inventors: Risaburo Yoshida, Keisuke Kaiho, Yusaku Ide, Kanji Noda, Tetsuya Yamagata, Hirotaka Kida