Patents by Inventor Thai Hiep Nguyen

Thai Hiep Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical salts of pyrimidine derivatives and method of treating disorders
    Patent number: 12084431
    Abstract: The present disclosure relates to pharmaceutical salts and polymorphic forms of pyrimidine derivatives that have inhibitory activities against mutant epidermal growth factor receptor (EGFR). The present disclosure further relates to the processes for the preparation of the pyrimidine derivatives and to the pharmaceutical salts and the polymorphic forms of the pyrimidine derivatives.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: September 10, 2024
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Landon J. Durak, Marianne Langston, Pradeep Kumar Sharma, Thai Hiep Nguyen, Shuanglian Li, Xiaoguang Zhang
  • PHARMACEUTICAL SALTS OF PYRIMIDINE DERIVATIVES AND METHOD OF TREATING DISORDERS
    Publication number: 20210309640
    Abstract: The present disclosure relates to pharmaceutical salts and polymorphic forms of forms of pyrimidine derivatives that have inhibitory activities against mutant epidermal growth factor receptor (EGFR). The present disclosure further relates to the processes for the preparation of the pyrimidine derivatives and to the pharmaceutical salts and the polymorphic forms of the pyrimidine derivatives.
    Type: Application
    Filed: May 13, 2019
    Publication date: October 7, 2021
    Inventors: Landon J. DURAK, Marianne Langston, Pradeep Kumar Sharma, Thai Hiep Nguyen, Shuanglian Li, Xiaoguang Zhang
  • 3-SUBSTITUTED-1H-INDOLE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
    Publication number: 20090311217
    Abstract: The invention relates to 3-substituted-1H-indole compounds of the Formula I: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
    Type: Application
    Filed: May 28, 2009
    Publication date: December 17, 2009
    Applicant: Wyeth
    Inventors: Matthew Gregory Bursavich, Nan Zhang, Semiramis Ayral-Kaloustian, James Thomas Anderson, Thai Hiep Nguyen, Sabrina Lombardi, David Malwitz, Natasja Brooijmans, Derek Cecil Cole, Adam Matthew Gilbert, Pawel Wojciech Nowak, Kaapjoo Park, Sasmita Das, Hwei-Ru Tsou, Aranapakam Mudumbai Venkatesan, Mercy Adufa Otteng, Gary Harold Birnberg, Gloria Jean MacEwan
  • 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
    Publication number: 20090298820
    Abstract: The invention relates to 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula 1: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
    Type: Application
    Filed: May 28, 2009
    Publication date: December 3, 2009
    Applicant: Wyeth
    Inventors: Hwei-Ru Tsou, Gary Harold Birnberg, Gloria Jean MacEwan, Semiramis Ayral-Kaloustian, Matthew Gregory Bursavich, Sabrina Lombardi, Nan Zhang, Adam Matthew Gilbert, George Theordore Grosu, Natasja Brooijmans, Thai Hiep Nguyen
  • 2-Aryl- and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof
    Publication number: 20090270363
    Abstract: The present invention discloses fused bicyclic 2-aryl- or 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumor growth in particular and to treat diseases or disorders associated with securin, including elevated securin levels.
    Type: Application
    Filed: March 27, 2009
    Publication date: October 29, 2009
    Applicant: Wyeth
    Inventors: Nan Zhang, Semiramis Ayral-Kaloustian, Tarek Suhayl Mansour, Thai Hiep Nguyen, Chuansheng Niu, Edward Christian Rosfjord, Ronald Suayan, Hwei-Ru Tsou
  • 2-Aryl-and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof
    Publication number: 20090270447
    Abstract: The present invention discloses fused heterobicyclic 2-aryl- and 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumor growth in particular and to treat diseases or disorders associated with securin.
    Type: Application
    Filed: March 27, 2009
    Publication date: October 29, 2009
    Applicant: Wyeth
    Inventors: Nan Zhang, Semiramis Ayral-Kaloustian, Thai Hiep Nguyen, Chuansheng Niu, Edward Christian Rosfjord, Ronald Suayan
  • [a]-FUSED INDOLE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
    Publication number: 20090192147
    Abstract: The invention relates to [a]-fused indole compounds of the Formula II, or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein. The invention also relates to compositions comprising the compounds of Formula II, and methods for making and using the compounds.
    Type: Application
    Filed: January 30, 2009
    Publication date: July 30, 2009
    Applicant: Wyeth
    Inventors: Semiramis Ayral-Kaloustian, Nan Zhang, Aranapakam Mudumbai Venkatesan, Tarek Suhayl Mansour, Thai Hiep Nguyen, James Thomas Anderson