Patents by Inventor Theodore M. Klein

Theodore M. Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100077514
    Abstract: The present invention provides a method of screening for the purpose of obtaining gene expression modulating elements and gene insulator elements. The invention includes a method of identifying gene expression modulating elements and gene insulator elements through use of the following steps: a) locating intergenic regions of a plant genome that are flanked by a gene on each side that have differing gene expressions b) taking that intergenic region or a portion of that intergenic region and adding it to a cassette comprising an isolated gene c) introducing the cassette into a plant cell d) analyzing expression of the isolated gene. The present invention also includes identified sequences that act as gene expression modulating elements.
    Type: Application
    Filed: November 30, 2009
    Publication date: March 25, 2010
    Applicant: E.I. du Pont de Nemours and Company
    Inventors: Hochul Yi, Theodore M. Klein, Joanne E. Barton
  • Patent number: 7655786
    Abstract: The present invention provides a method of screening for the purpose of obtaining gene expression modulating elements and gene insulator elements. The invention includes a method of identifying gene expression modulating elements and gene insulator elements through use of the following steps: a) locating intergenic regions of a plant genome that are flanked by a gene on each side that have differing gene expressions b) taking that intergenic region or a portion of that intergenic region and adding it to a cassette comprising an isolated gene c) introducing the cassette into a plant cell d) analyzing expression of the isolated gene. The present invention also includes identified sequences that act as gene expression modulating elements.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: February 2, 2010
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Hochul Yi, Theodore M. Klein, Joanne E. Barton
  • Publication number: 20090249517
    Abstract: The preparation and use of nucleic acid fragments useful in altering the phenotype in plants are disclosed. Chimeric constructs incorporating such nucleic acid fragments and suitable regulatory sequences can be used to create transgenic plants having altered phenotypes. Methods for altering the phenotype of plants using such nucleic acid fragments also are disclosed.
    Type: Application
    Filed: April 24, 2009
    Publication date: October 1, 2009
    Inventors: Stephen M. Allen, William B. Allen, Rebecca E. Cahoon, Sabine Epelbaum, Omolaya O. Famodu, Leslie T. Harvell, Todd J. Jones, Anthony J. Kinney, Theodore M. Klein, Changjiang Li, Igor Cunha Oliveira, Hajime Sakai, Bo Shen, Mitchell C. Tarczynski
  • Publication number: 20090235391
    Abstract: The preparation and use of nucleic acid fragments useful in altering the oil phenotype in plants are disclosed. Chimeric constructs incorporating such nucleic acid fragments and suitable regulatory sequences can be used to create transgenic plants having altered lipid profiles. Methods for altering the oil phenotype in plants using such nucleic acid fragments also are disclosed.
    Type: Application
    Filed: April 24, 2009
    Publication date: September 17, 2009
    Inventors: Stephen M. Allen, William B. Allen, Rebecca E. Cahoon, Sabine Epelbaum, Omolayo O. Famodu, Leslie T. Harvell, Todd J. Jones, Anthony J. Kinney, Theodore M. Klein, Changjiang Li, Igor Cunha Oliveira, Hajime Sakai, Bo Shen, Mitchell C. Tarczynski
  • Publication number: 20080216201
    Abstract: The present invention provides a method of screening for the purpose of obtaining gene expression modulating elements and gene insulator elements. The invention includes a method of identifying gene expression modulating elements and gene insulator elements through use of the following steps: a) locating intergenic regions of a plant genome that are flanked by a gene on each side that have differing gene expressions b) taking that intergenic region or a portion of that intergenic region and adding it to a cassette comprising an isolated gene c) introducing the cassette into a plant cell d) analyzing expression of the isolated gene. The present invention also includes identified sequences that act as gene expression modulating elements.
    Type: Application
    Filed: March 13, 2007
    Publication date: September 4, 2008
    Applicant: E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Hochul Yi, Theodore M. Klein, Joanne E. Barton
  • Publication number: 20080109925
    Abstract: The invention provides isolated nucleic acids and their encoded proteins that act as cell transcription inhibitors and methods of use thereof. The invention further provides expression cassettes, transformed host cells, transgenic plants and plant parts, and antibody compositions.
    Type: Application
    Filed: July 18, 2007
    Publication date: May 8, 2008
    Applicant: PIONEER HI-BRED INTERNATIONAL INC.
    Inventors: Yumin Tao, William J. Gordon-Kamm, Bo Shen, Keith S. Lowe, Olga N. Danilevskaya, Pramod B. Mahajan, Jan Antoni Rafalski, Hajime Sakai, Theodore M. Klein
  • Patent number: 7220894
    Abstract: The invention provides methods of transforming plants and plant cells including recalcitrant cells with isolated nucleic acids encoding LEC1 transcriptional activators to induce transformation or regeneration efficiency, apomixis or somatic embryogenesis.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: May 22, 2007
    Assignees: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Keith S. Lowe, William J. Gordon-Kamm, Theodore M. Klein, Sonriza Rasco-Gaunt, Xifan Sun, George J. Hoerster
  • Patent number: 7166765
    Abstract: The invention provides isolated nucleic acids and their encoded proteins which act as transcriptional activators and methods of use thereof. The invention further provides expression cassettes, transformed host cells, transgenic plants and plant parts.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: January 23, 2007
    Assignees: Pioneer Hi-Bred International, Inc., E. I. du Pont de Nemours and Company
    Inventors: Keith S. Lowe, William J. Gordon-Kamm, Theodore M. Klein, Sonriza Rasco-Gaunt, Rebecca E. Cahoon, Xifan Sun, George J. Hoerster, Carolyn Gregory, Ramgopal Nadimpalli, Yumin Tao
  • Patent number: 7157621
    Abstract: The preparation and use of nucleic acid fragments useful in altering the oil phenotype in plants are disclosed. Chimeric construct incorporating such nucleic acid fragments and suitable regulatory sequences can be used to create transgenic plants having altered lipid profiles. Methods for altering the oil phenotype in plants using such nucleic acid fragments also are disclosed.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: January 2, 2007
    Assignees: E. I. du Pont de Nemours and Company, Pioneer Hi-Bred International, Inc.
    Inventors: Stephen M. Allen, William B. Allen, Rebecca E. Cahoon, Sabine Epelbaum, Omolayo O. Famodu, Leslie T. Harvell, Todd J. Jones, Anthony J. Kinney, Theodore M. Klein, Changjiang Li, Igor Cunha Oliveira, Hajime Sakai, Bo Shen, Mitchell C. Tarczynski
  • Patent number: 7087813
    Abstract: This invention relates to isolated nucleic acid fragments encoding lipoxygenases. The invention also relates to the construction of recombinant DNA constructs encoding all or a portion of the lipoxygenase, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of the lipoxygenase in a transformed host cell.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: August 8, 2006
    Assignee: E.I. du Pont de nemours and Company
    Inventors: Anthony J. Kinney, Theodore M. Klein, Jian-Ming Lee, Richard W. Pearlstein, J. Antoni Rafalski, Jennie Bih-Jien Shen, Catherine J. Thorpe, Scott V. Tingey
  • Patent number: 7071382
    Abstract: This invention relates to an isolated nucleic acid fragment encoding an apoptosis inhibitory protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the apoptosis inhibitory protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the apoptosis inhibitory protein in a transformed host cell.
    Type: Grant
    Filed: October 7, 2003
    Date of Patent: July 4, 2006
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Rebecca E. Cahoon, Perry G. Caimi, Theodore M. Klein, Michele Morgante, Hajime Sakai, Jennie Bih-Jien Shen, Scott V. Tingey
  • Patent number: 6825397
    Abstract: The invention provides isolated polynucleotides and their encoded proteins which act as transcriptional activators and methods of use thereof. The invention further provides expression cassettes, transformed host cells, transgenic plants and plant parts.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: November 30, 2004
    Assignees: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Keith S. Lowe, William J. Gordon-Kamm, Theodore M. Klein, Sonriza Rasco-Gaunt, Rebecca E. Cahoon, Xifan Sun, George J. Hoerster, Carolyn A. Gregory, Ramgopal Nadimpalli
  • Publication number: 20040168217
    Abstract: The invention provides isolated nucleic acids and their encoded proteins which act as transcriptional activators and methods of use thereof. The invention further provides expression cassettes, transformed host cells, transgenic plants and plant parts, and antibody compositions.
    Type: Application
    Filed: December 22, 2003
    Publication date: August 26, 2004
    Applicants: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Keith S. Lowe, William J. Gordon-Kamm, Theodore M. Klein, Sonriza Rasco-Gaunt, Xifan Sun, George J. Hoerster
  • Publication number: 20040111767
    Abstract: This invention relates to an isolated nucleic acid fragment encoding an apoptosis inhibitory protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the apoptosis inhibitory protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the apoptosis inhibitory protein in a transformed host cell.
    Type: Application
    Filed: October 7, 2003
    Publication date: June 10, 2004
    Inventors: Rebecca E. Cahoon, Perry G. Caimi, Theodore M. Klein, Michele Morgante, Hajime Sakai, Jennie Bih-Jien Shen, Scott V. Tingey
  • Publication number: 20040098760
    Abstract: The invention provides isolated nucleic acids and their encoded proteins that act as cell transcription inhibitors and methods of use thereof. The invention further provides expression cassettes, transformed host cells, transgenic plants and plant parts, and antibody compositions.
    Type: Application
    Filed: September 30, 2003
    Publication date: May 20, 2004
    Applicants: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company
    Inventors: Yumin Tao, William J. Gordon-Kamm, Bo Shen, Keith S. Lowe, Olga N. Danilevskaya, Pramod B. Mahajan, Jan Antoni Rafalski, Hajime Sakai, Theodore M. Klein
  • Publication number: 20040053285
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a transcription factor. The invention also relates to the construction of a chimeric gene encoding all or a portion of the transcription factor, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of accumulated oil in a transformed host cell.
    Type: Application
    Filed: April 22, 2003
    Publication date: March 18, 2004
    Inventors: Rebecca E. Cahoon, Theodore M. Klein
  • Publication number: 20030204870
    Abstract: The preparation and use of nucleic acid fragments useful in altering the oil phenotype in plants are disclosed. Chimeric construct incorporating such nucleic acid fragments and suitable regulatory sequences can be used to create transgenic plants having altered lipid profiles. Methods for altering the oil phenotype in plants using such nucleic acid fragments also are disclosed.
    Type: Application
    Filed: June 27, 2002
    Publication date: October 30, 2003
    Inventors: Stephen M. Allen, William B. Allen, Rebecca E. Cahoon, Sabine Epelbaum, Omolayo O. Famodu, Leslie T. Harvell, Todd J. Jones, Anthony J. Kinney, Theodore M. Klein, Changjiang Li, Igor Cunha Oliveira, Hajime Sakai, Bo Shen, Mitchell C. Tarczynski
  • Patent number: 6570067
    Abstract: The invention provides a method for producing stably transformed dicotyledonous plants, via the introduction of a foreign DNA, containing an expression vector carrying a gene of interest, into dicotyledonous cells via one or more microparticle bombardments to produce transformed dicotyledonous cells; followed by the regeneration of a stably transformed fertile dicotyledonous plant from the transformed dicotyledonous cells.
    Type: Grant
    Filed: July 30, 1999
    Date of Patent: May 27, 2003
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Dwight T. Tomes, Arthur Weissinger, John C. Sanford, Theodore M. Klein
  • Publication number: 20030074693
    Abstract: This invention relates to isolated nucleic acid fragments encoding lipoxygenases. The invention also relates to the construction of recombinant DNA constructs encoding all or a portion of the lipoxygenase, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of the lipoxygenase in a transformed host cell.
    Type: Application
    Filed: January 29, 2002
    Publication date: April 17, 2003
    Inventors: Edgar B. Cahoon, Anthony J. Kinney, Theodore M. Klein, Jian-Ming Lee, Richard W. Pearlstein, J. Antoni Rafalski, Jennie Bih-Jien Shen, Catherine J. Thorpe, Scott V. Tingey, Zude Weng
  • Publication number: 20020182704
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a proteinase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the proteinase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the proteinase in a transformed host cell.
    Type: Application
    Filed: February 15, 2002
    Publication date: December 5, 2002
    Inventors: Saverio Carl Falco, Edgar B. Cahoon, Omolayo O. Famodu, Theodore M. Klein, Emil M. Orozco, J. Antoni Rafalski, Jennie Bih-Jien Shen, Hajime Sakai