Patents by Inventor Theresa Williams

Theresa Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120040998
    Abstract: The present invention is directed to 2-alkylpiperidines which are positive allosteric modulators of metabotropic glutamate receptors, particularly the mGluR5 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
    Type: Application
    Filed: April 22, 2010
    Publication date: February 16, 2012
    Inventors: Swati P. Mercer, Anthony J. Roecker, Theresa Williams, Xu-Fang Zhang
  • Publication number: 20080070899
    Abstract: The present invention is directed to compounds of Formula I: Formula I: I and Formula II: (where variables R1, R2, R3, R4, A, B, J, Q, T, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: October 5, 2005
    Publication date: March 20, 2008
    Inventors: Christopher Burgey, James Deng, Craig Potteiger, Theresa Williams
  • Publication number: 20070293470
    Abstract: The present invention is directed to compounds of Formula I: I (where variables A1, A2, B, J, K, m, n, R4, R5a, R5b and R5c are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: September 9, 2005
    Publication date: December 20, 2007
    Inventors: Theresa Williams, Christopher Burgey, Thomas Tucker, Craig Stump, Ian Bell
  • Publication number: 20070287696
    Abstract: Compounds of Formula I: and Formula II: (where variables R1, R2, R3, R4, A, B, D, G, J, Q, T, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, pharmaceutical compositions comprising these compounds, use of these compounds and compositions to prevent or treat diseases involving CGRP.
    Type: Application
    Filed: January 25, 2005
    Publication date: December 13, 2007
    Inventors: Christopher Burgey, Daniel Paone, Anthony Shaw, Craig Stump, Theresa Williams
  • Publication number: 20070225272
    Abstract: The present invention is directed to compounds of Formula I: and Formula II: (where variables R1, R2, R3, R4, A, B, G, J, Q, T, U, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: March 14, 2007
    Publication date: September 27, 2007
    Inventors: Christopher Burgey, Zhengwu Deng, Diem Nguyen, Daniel Paone, Anthony Shaw, Theresa Williams
  • Publication number: 20070173525
    Abstract: The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a benzazocine moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
    Type: Application
    Filed: April 2, 2007
    Publication date: July 26, 2007
    Inventors: Annette Kim, Craig Stump, Christopher Dinsmore, Samuel Graham, Theresa Williams, Diem Nguyen, B. Trotter
  • Publication number: 20060194783
    Abstract: The present invention is directed to compounds of Formula I and Formula II: (where variables R1, R2, R3, R4, R6, A, B, G, J, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: April 9, 2004
    Publication date: August 31, 2006
    Inventors: Christopher Burgey, Daniel Paone, Anthony Shaw, Theresa Williams
  • Publication number: 20060189600
    Abstract: The present invention is directed to compounds that are antagonists of CGRP receptors and that are useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: March 10, 2004
    Publication date: August 24, 2006
    Inventors: Ian Bell, Samuel Graham, Theresa Williams, Craig Stump
  • Publication number: 20060148779
    Abstract: The present invention is directed to compounds that are antagonists of CGRP receptors and that are useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: March 10, 2004
    Publication date: July 6, 2006
    Inventors: Ian Bell, Cory Theberge, Theresa Williams, C. Blair Zartman, Xu-Fang Zhang, Steven Gallicchio
  • Publication number: 20060148790
    Abstract: The present invention is directed to compounds of Formula I: (where variables R1, R2, R3, R6, R7, G, J, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: June 24, 2004
    Publication date: July 6, 2006
    Inventors: Christopher Burgey, Craig Stump, Theresa Williams
  • Publication number: 20050256098
    Abstract: The present invention is directed to compounds of Formula I: and Formula II: (where variables R1, R2, R3, R4, A, B, G, J, Q, T, U, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: June 14, 2005
    Publication date: November 17, 2005
    Inventors: Christopher Burgey, Zhengwu Deng, Diem Nguyen, Daniel Paone, Anthony Shaw, Theresa Williams
  • Publication number: 20050239815
    Abstract: The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a benzazocine moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
    Type: Application
    Filed: April 8, 2003
    Publication date: October 27, 2005
    Inventors: Annette Kim, Craig Stump, Christopher Dinsmore, Samuel Graham, Theresa Williams, Diem Nguyen, B. Wesley Trotter
  • Patent number: D679095
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: April 2, 2013
    Inventors: Theresa Williams, Kenneth Williams