Patents by Inventor Thomas A. Michel

Thomas A. Michel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10844733
    Abstract: An aviation turbine blade extending in the radial direction and presenting a pressure side and a suction side, including a plurality of pressure side cavities extending radially at the pressure side of the blade, a plurality of suction side cavities extending radially at the suction side of the blade, and at least one central cavity located in the central portion of the blade and surrounded by pressure side cavities and by suction side cavities, the blade further including a plurality of cooling circuits, in which at least a first cooling circuit comprises: a first cavity and a second cavity, the first and second cavities communicating with each other at a radially inner end and at a radially outer end of the blade.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: November 24, 2020
    Assignee: SAFRAN
    Inventors: Adrien Bernard Vincent Rollinger, Romain Pierre Cariou, Thomas Michel Flamme, Sylvain Paquin
  • Patent number: 10845619
    Abstract: A method for producing a spectacle lens by additive manufacturing includes interspersing first volume elements and second volume elements. The first and second volume elements are arranged on the grid points of a geometric grid to form a first sub-grid and a second sub-grid, respectively. The first sub-grid forms the first part of the spectacle lens having a dioptric effect for vision for a first object distance and the second sub-grid forms the second part of the spectacle lens having a dioptric effect for vision for a second object distance, which differs from the first object distance.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: November 24, 2020
    Assignee: Carl Zeiss Vision International GmbH
    Inventors: Timo Mappes, Matthias Hornauer, Georg Michels, Thomas Glöge
  • Publication number: 20200360332
    Abstract: Compound, stereoisomers, enantiomers or diastereomers thereof, physiologically acceptable salts thereof, mixtures of said compound for use in increasing mental capability, and a pharmaceutical composition. The increasing of mental capability is tested in learning experiments with Drosophila melanogaster larvae or older animals, which are raised with standard feed mash or with different concentrations of FSE-20 in the feed mash. In the learning experiment, the animals are each subjected to one of two inverse training regimens and then subjected to a test. In the training, a first scent was presented with the feed reward to the first group, while a second scent was presented alone to the first group. The second group was trained inversely. In the test of the learning experiment, it was subsequently examined whether the larvae of both groups prefer the first scent or the second scent in a selection situation; thus, their learning and memory capability was determined.
    Type: Application
    Filed: November 23, 2018
    Publication date: November 19, 2020
    Inventors: Birgit Michels, Bertram Gerber, Ludger Wessjohann, Katrin Franke, Stephan Sigrist, Anuradha Bhukel, Oleh Lushchak, Hanna Zwaka, Ruth Bartels, Alexander Dityatev, Inseon Song, Markus Fendt, Volkmar Lessmann, Thomas Endres, Thilo Kaehne
  • Patent number: 10836358
    Abstract: The invention proposes a wiper blade (10) of a motor vehicle, comprising a heating electrical circuit (30) comprising at least one heating resistive element, which is connected to terminals (36) for supplying electric current, and a component for regulating the electric power supply current, which is a resettable fuse with a positive temperature coefficient (50), known as a PTC fuse. The PTC fuse (50) is, for example, a surface-mounted component, known as a CMS component, which is electrically connected to two belonging electrical connecting areas (44, 46).
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: November 17, 2020
    Assignees: Valeo Systemes d'Essuyage, Enmech GmbH
    Inventors: Vincent Izabel, Gérald Caillot, Jean-Michel Jarasson, Dmitry Filatov, Thomas Leben, Olaf Runge
  • Patent number: 10809949
    Abstract: A verifier and printer assembly are provided. The verifier and printer assembly include a verifier module and a printer. The verifier has a magnetic docking element and the printer includes a docking portion operable to dock the verifier module. The magnetic docking element and the docking portion interact with each other to removably couple the verifier module to the printer. A magnetic attachment system for the verifier module and methods for removably coupling the verifier module and the printer for verification of a printed machine-readable symbol are also provided.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: October 20, 2020
    Assignee: DATAMAX-O'NEIL CORPORATION
    Inventors: Chin Young Wong, Thomas Axel Jonas Celinder, Sébastien Michel Marie Joseph d'Armancourt
  • Patent number: 10799813
    Abstract: A chromatography system includes a first chromatography column for receiving and separating a flow stream, a plurality of traps configured to trap a plurality of distinct flow segments exiting the first chromatography column during separation of the flow stream, and a second chromatography column operatively associated with the plurality of traps for receiving and separating the distinct flow segments. The system can include at-column dilution at trapping and separating stages thereof. A chromatography method for operating the chromatographic system includes measuring a plurality of time segments corresponding to a plurality of peaks of a fluid sample flowing through the first chromatographic column, and sequentially fluidly coupling the plurality of distinct flow segments with the corresponding plurality of traps during time segments corresponding to the plurality of peaks.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: October 13, 2020
    Assignee: Waters Technologies Corporation
    Inventors: Amanda B. Dlugasch, Thomas E. Wheat, Daniel Root, Jean-Michel Plankeele, Isabelle Francois, Edward R. Aig
  • Publication number: 20200299379
    Abstract: The present disclosure relates to antibodies and proteins comprising an antigen-binding portion thereof that specifically bind to the pro-inflammatory cytokine IL-17 A. The disclosure more specifically relates to specific antibodies and proteins that are IL-17 A antagonists (inhibit the activities of IL-17 A and IL-17 AF) and are capable of inhibiting IL-17 A induced cytokine production in in vitro assays, and having an inhibitory effect in an antigen-induced arthritis model in vivo. The disclosure further relates to compositions and methods of use for said antibodies and proteins to treat pathological disorders that can be treated by inhibiting IL-17A or IL 17AF mediated activity, such as rheumatoid arthritis, psoriasis, systemic lupus erythematosus (SLE), lupus nephritis, chronic obstructive pulmonary disease, asthma or cystic fibrosis or other autoimmune and inflammatory disorders.
    Type: Application
    Filed: April 30, 2020
    Publication date: September 24, 2020
    Inventors: Franco E. DI PADOVA, Thomas HUBER, Jean-Michel Rene RONDEAU
  • Patent number: 10781706
    Abstract: When cold and in the non-coated state, the aerodynamic profile is substantially identical to a nominal profile determined by the Cartesian coordinates X,Y, Zadim given in Table 1, in which the coordinate Zadim is the quotient D/H where D is the distance of the point under consideration from a first reference plane P0 situated at the base of the nominal profile, and H is the height of said profile measured from the first reference plane to a second reference plane P1. The measurements D and H are taken radially relative to the axis of the turbine, while the X coordinate is measured in the axial direction of the turbine.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: September 22, 2020
    Assignee: SAFRAN AIRCRAFT ENGINES
    Inventors: Guillaume Jochen Scholl, Daniel Marius Man, Thomas Michel Julien Mervant, Ludovic Pintat, Renaud Gabriel Constant Royan
  • Publication number: 20200261465
    Abstract: Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds (“diaminophenothiazinium compounds”) including Methylthioninium Chloride (MTC) (Methylene Blue), and the resulting high purity characterized by a purity greater than 98%, and very low levels of heavy metals and organic impurities Azure A, B, C and MVB. Also disclosed are methods of treatment of a tauopathy or methemoglobinemia in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of the high-purity diaminophenothiazinium compound.
    Type: Application
    Filed: November 15, 2019
    Publication date: August 20, 2020
    Inventors: Claude Michel Wischik, John Mervyn David Storey, Colin Marshall, James Peter Sinclair, Thomas Craven Baddeley
  • Patent number: 10738633
    Abstract: When cold and in the non-coated state, the aerodynamic profile is substantially identical to a nominal profile determined by the Cartesian coordinates X,Y, Zadim given in Table 1, in which the coordinate Zadim is the quotient D/H where D is the distance of the point under consideration from a first reference plane P0 situated at the base of the nominal profile, and H is the height of said profile measured from the first reference plane to a second reference plane P1. The measurements D and H are taken radially relative to the axis of the turbine, while the X coordinate is measured in the axial direction of the turbine.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: August 11, 2020
    Assignee: Safran Aircraft Engines
    Inventors: Maxime Didier Delabriere, Ludovic Pintat, Thomas Michel Julien Mervant, Guillaume Jochen Scholl, Renaud Gabriel Constant Royan
  • Publication number: 20200246350
    Abstract: Disclosed are compounds of general formula (I): and pharmaceutically acceptable salts thereof, formulations, methods and uses in, for example, the treatment of disease.
    Type: Application
    Filed: January 24, 2020
    Publication date: August 6, 2020
    Inventors: Colin Marshall, Scott Clunas, John Mervyn David Storey, James Peter Sinclair, Thomas Craven Baddeley, Ahtsham Ishaq, Michael Simpson, Craig Williamson, Barry Alan Wood, Claude Michel Wischik, Charles Robert Harrington, Janet Elizabeth Rickard, David Horsley, Yin Sze Loh, Karrar Ahmad Khan, Christopher Paul Larch
  • Publication number: 20200244478
    Abstract: A data system of a towing vehicle and/or trailer vehicle includes a control device, a sensor system configured to record and process sensor data, and a BUS system configured to transfer the sensor data between the control device and the sensor system. The BUS system has a first BUS device in the form of a CAN BUS and a second BUS device in the form of an ETHERNET BUS, and the BUS system further has a first interface configured to transfer the sensor data to a second interface of a second BUS system of a second data system of a second towing vehicle and/or trailer vehicle. The data system additionally includes an intelligent switch, coupled to the control device and/or to the first interface, the intelligent switch being configured to couple the first towing vehicle and/or trailer vehicle to the second towing vehicle and/or trailer vehicle in a coordinated manner.
    Type: Application
    Filed: August 15, 2018
    Publication date: July 30, 2020
    Inventors: Thomas Dieckmann, Andreas Goers, Sebastian Kuehne, Ralph-Carsten Luelfing, Marco Michel, Thomas Wolf, Oliver Wulf
  • Publication number: 20200223442
    Abstract: A method for operating an engine of a vehicle, in which after an execution of an automated gear change of a transmission of the vehicle, an acceleration force for accelerating the vehicle is requested when a force value representing a present drive force of the engine is in a tolerance band around a reference value determined before the gear change and a request signal for the acceleration force exists.
    Type: Application
    Filed: January 7, 2020
    Publication date: July 16, 2020
    Inventors: Andreas Schultz, Benjamin Pfeil, Leo Michels, Thomas Brettschneider
  • Patent number: 10711627
    Abstract: When cold and in the non-coated state, the aerodynamic profile is substantially identical to a nominal profile determined by the Cartesian coordinates X,Y, Zadim given in Table 1, in which the coordinate Zadim is the quotient D/H where D is the distance of the point under consideration from a first reference plane P0 situated at the base of the nominal profile, and H is the height of said profile measured from the first reference plane to a second reference plane P1. The measurements D and H are taken radially relative to the axis of the turbine, while the X coordinate is measured in the axial direction of the turbine.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: July 14, 2020
    Assignee: Safran Aircraft Engines
    Inventors: Ludovic Pintat, Pierre Ginibre, Vincent Nicolas Leonardon, Pierre Hervé Fernand Marche, Thomas Michel Julien Mervant
  • Patent number: 10710731
    Abstract: In an aeroengine comprising a gas turbine engine driving a propeller via a reduction gearbox, the propeller comprising a plurality of blades, each provided with one or more electrical deicer elements and being set into rotation by a propeller-carrying shaft passing through the gearbox, the propeller-carrying shaft having a fastener flange for fastening to the propeller, provision is made, in order to deliver the electrical power needed for powering said electrical deicer elements, for the aeroengine to include a rotary three-phase transformer set into rotation by the propeller-carrying shaft and comprising firstly a rotor mounted inside the propeller-carrying shaft and angularly secured thereto, and secondly a stator secured to a stationary portion of the aeroengine, the rotary three-phase transformer being arranged behind the propeller fastener flange.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: July 14, 2020
    Assignees: SAFRAN AIRCRAFT ENGINES, SAFRAN TRANSMISSION SYSTEMS, SAFRAN ELECTRICAL & POWER
    Inventors: Mathieu Jean Jacques Santin, Guillaume Julien Beck, Aldric Renaud Gabriel Marie Moreau De Lizoreux, Boris Pierre Marcel Morelli, Jean-Michel Bernard Paul Chastagnier, Thomas Turchi
  • Publication number: 20200216374
    Abstract: Various embodiments of the present invention are directed to methods of preparing a biogas purification system. Embodiments include flushing an adsorber with a gas stream that is separable by the downstream biogas purification process. Other embodiments include using the separable gas stream to flush a saturated adsorber. Additional embodiments include using a gas stream comprised of CO2.
    Type: Application
    Filed: March 20, 2020
    Publication date: July 9, 2020
    Applicant: CALGON CARBON CORPORATION
    Inventors: Franck Michel HONORE, Thomas Anthony RYAN
  • Publication number: 20200208098
    Abstract: The invention relates to a method for selecting a yeast strain having improved capability for fermenting a pentose, advantageously xylose, in the presence of organic acid, advantageously acetic acid, in non-dissociated form, in which at least one yeast strain that is capable of fermenting said pentose is consecutively cultured in the following two media: a first growth medium comprising said pentose as the only carbon source and said organic acid in non-dissociated form; a second growth medium comprising another carbon source as the only carbon source, advantageously glucose, free of said organic acid in non-dissociated form, the consecutive culture in at least said two growth media being repeated at least twice, in the presence of rising concentrations of organic acid in non-dissociated form.
    Type: Application
    Filed: February 18, 2020
    Publication date: July 2, 2020
    Inventors: Jean-Michel Bavouzet, Thomas Desfougeres, Georges Pignede, Jennifer Techel
  • Patent number: 10683767
    Abstract: When cold and in the non-coated state, the aerodynamic profile is substantially identical to a nominal profile determined by the Cartesian coordinates X,Y, Zadim given in Table 1, in which the coordinate Zadim is the quotient D/H where D is the distance of the point under consideration from a first reference plane P0 situated at the base of the nominal profile, and H is the height of said profile measured from the first reference plane to a second reference plane P1. The measurements D and H are taken radially relative to the axis of the turbine, while the X coordinate is measured in the axial direction of the turbine.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: June 16, 2020
    Assignee: Safran Aircraft Engines
    Inventors: Ludovic Pintat, Pierre Hervé Fernand Marche, Guillaume Jochen Scholl, Thomas Michel Julien Mervant, Renaud Gabriel Constant Royan
  • Patent number: 10683349
    Abstract: The present disclosure relates to antibodies and proteins comprising an antigen-binding portion thereof that specifically bind to the pro-inflammatory cytokine IL-17 A. The disclosure more specifically relates to specific antibodies and proteins that are IL-17 A antagonists (inhibit the activities of IL-17 A and IL-17 AF) and are capable of inhibiting IL-17 A induced cytokine production in in vitro assays, and having an inhibitory effect in an antigen-induced arthritis model in vivo. The disclosure further relates to compositions and methods of use for said antibodies and proteins to treat pathological disorders that can be treated by inhibiting IL-17A or IL 17AF mediated activity, such as rheumatoid arthritis, psoriasis, systemic lupus erythematosus (SLE), lupus nephritis, chronic obstructive pulmonary disease, asthma or cystic fibrosis or other autoimmune and inflammatory disorders.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: June 16, 2020
    Assignee: NOVARTIS AG
    Inventors: Franco E. Di Padova, Thomas Huber, Jean-Michel Rene Rondeau
  • Patent number: 10668406
    Abstract: The present disclosure relates to an enhanced multi-dimensional chromatography system and method using selectable At-Column Dilution to improve compatibility of the interface and transfer between the multiple dimensions. The use of At-Column Dilution (“ACD”) with multi-dimensional chromatography can provide greater retention of the diverted components on subsequent stationary phases, and increase the sensitivity and peak shape of the component(s) separated on subsequent dimensions.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: June 2, 2020
    Assignee: Waters Technologies Corporation
    Inventors: Amanda B. Dlugasch, Thomas E. Wheat, Dan Root, Jean-Michel Plankeele, Isabelle Francois, Edward R. Aig