Patents by Inventor Thomas Bär

Thomas Bär has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydropyridothiophenes
    Patent number: 7723523
    Abstract: Compounds of a certain formula (I) in which Ra and Rb have the meanings indicated in the description, are novel, effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: May 25, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Thomas Baer, Björn Bartels, Mathias Schmidt, Thomas Beckers
  • Benzothienopyridines for use as inhibitors of Eg5 kinesin
    Patent number: 7718665
    Abstract: Compounds of the formula (1) in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: May 18, 2010
    Assignee: 4SC AG
    Inventors: Matthias Vennemann, Thomas Baer, Gudrun Groegor, Jürgen Braunger, Petra Gimmnich, Thomas Maier, Heike Rothfels
  • Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
    Patent number: 7714135
    Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: May 11, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Björn Bartels
  • Compounds and use of tetrahydropyridothiophenes
    Patent number: 7714134
    Abstract: The compounds of a certain formula (1) in which Ra and Rb have the meanings indicated in the description are novel for treating hyperproliferative diseases and/or disorders responsive to the induction of apoptosis. The invention further relates to certain compounds of formula (I), in which Ra and Rb have the meanings indicated in the description.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: May 11, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Thomas Baer, Mathias Schmidt, Thomas Beckers
  • Tetrahydropyridothiophenes
    Patent number: 7714136
    Abstract: Compounds of a certain formula (I) in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: May 11, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Petra Gimmnich
  • BENZOPYRANOPYRAZOLES
    Publication number: 20100104659
    Abstract: Compounds of a certain formula I, in which Ra, Rb and Rc have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: July 12, 2007
    Publication date: April 29, 2010
    Inventors: Matthias Vennemann, Thomas Bär, Thomas Maier, Andreas Lindenmaier, Jürgen Braunger, Markus Boehm, Astrid Zimmermann, Volker Gekeler
  • N-SULPHONYLPYRROLES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS
    Publication number: 20100074862
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Application
    Filed: December 1, 2009
    Publication date: March 25, 2010
    Inventors: Thomas MAIER, Thomas BÄR, Thomas BECKERS, Astrid ZIMMERMANN, Siegfried SCHNEIDER, Volker GEKELER
  • N-sulphonylpyrroles and their use as histone deacetylase inhibitors
    Patent number: 7666868
    Abstract: Compounds of a certain formula (I) in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: February 23, 2010
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Bär, Thomas Beckers, Astrid Zimmermann, Siegfried Schneider, Volker Gekeler
  • Sulphonylpyrrole Hydrochloride Salts as Histone Deacetylases Inhibitors
    Publication number: 20090297473
    Abstract: Compounds of a certain formula 1, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.
    Type: Application
    Filed: September 8, 2006
    Publication date: December 3, 2009
    Applicant: Nycomed GmbH
    Inventors: Thomas Maier, Thomas Beckers, Rolf-Peter Hummel, Martin Feth, Matthias Müller, Thomas Bär
  • 3' Biased Detection of Nucleic Acids
    Publication number: 20090270271
    Abstract: The invention provides materials and methods for the detection of nucleic acid expression via the 3? portion of expressed sequences. Embodiments of the invention include the use of microarrays comprising nucleic acid probes that are complementary to the 3? end of expressed sequences and by the use of quantitative PCR (Q-PCR) based amplification of sequences found at or near the 3? end of expressed sequences. The invention may be used to detect the presence of expressed nucleic acids encoding particular gene products (sequences present in a “transcriptome”).
    Type: Application
    Filed: September 15, 2008
    Publication date: October 29, 2009
    Inventors: Mark G. Erlander, Xiao-Jun Ma, Thomas Baer
  • NOVEL TETRAHYDROPYRIDOTHIOPHENES
    Publication number: 20090270378
    Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: March 26, 2009
    Publication date: October 29, 2009
    Applicant: NYCOMED GMBH
    Inventors: Klaus PEKARI, Thomas BAER, Bjoern BARTELS, Mathias SCHMIDT, Thomas BECKERS
  • NOVEL COMPOUNDS AND USE OF TETRAHYDROPYRIDOPYRIDOTHIOPHENES
    Publication number: 20090209534
    Abstract: The use of tetrahydropyridothiophenes of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, is novel for treating hyperproliferative diseases and/or disorders responsive to the induction of apoptosis.
    Type: Application
    Filed: March 27, 2009
    Publication date: August 20, 2009
    Inventors: Klaus PEKARI, Thomas Baer, Mathias Schmidt, Thomas Beckers
  • Tetrahydropyridothiophenes For Use In The Treatment Of Cancer
    Publication number: 20090163538
    Abstract: Compounds of formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: February 23, 2009
    Publication date: June 25, 2009
    Inventors: Klaus PEKARI, Thomas BAER, Mathias SCHMIDT, Thomas BECKERS
  • Tetrahydropyridothiophenes for use in the treatment of cancer
    Patent number: 7517986
    Abstract: Compounds of the formula (I) in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: April 14, 2009
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Thomas Baer, Mathias Schmidt, Thomas Beckers
  • Novel Compounds and Use of Tetrahydropyridothiophenes
    Publication number: 20070259911
    Abstract: The compounds of a certain formula (1) in which Ra and Rb have the meanings indicated in the description are novel for treating hyperproliferative diseases and/or disorders responsive to the induction of apoptosis. The invention further relates to certain compounds of formula (I), in which Ra and Rb have the meanings indicated in the description.
    Type: Application
    Filed: June 10, 2005
    Publication date: November 8, 2007
    Inventors: Klaus Pekari, Thomas Baer, Mathias Schmidt, Thomas Beckers
  • Novel Pyrazolopyrimidines
    Publication number: 20070254046
    Abstract: Compounds of a certain formula I in which R1, R2, R3 and R4 have the meanings indicated in the description are novel compounds expected to be useful in the therapy of (hyper)proliferative diseases and/or disorders responsive to induction of apoptosis.
    Type: Application
    Filed: September 5, 2005
    Publication date: November 1, 2007
    Applicant: Altana Pharma AG
    Inventors: Thomas Maier, Armin Zuelch, Thomas Ciossek, Thomas Baer, Thomas Beckers
  • Novel tetrahydropyridothiophenes
    Publication number: 20070244112
    Abstract: Compounds of a certain formula (I) in which Ra and Rb have the meanings indicated in the description, are novel, effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: May 25, 2005
    Publication date: October 18, 2007
    Applicant: Altana Pharma AG
    Inventors: Klaus Pekari, Thomas Baer, Bjorn Bartels, Mathias Schmidt, Thomas Beckers
  • Benzothienopyridines for Use as Inhibitors of Eg5 Kinesin
    Publication number: 20070232596
    Abstract: Compounds of the formula (1) in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: August 17, 2005
    Publication date: October 4, 2007
    Applicant: Altana Pharma AG
    Inventors: Matthias Vennemann, Thomas Baer, Gudrun Groegor, Jurgen Braunger, Petra Gimmnich, Thomas Maier, Heike Rothfels
  • Tetrahydropyridothiophenes for Use in the Treatment of Cancer
    Publication number: 20070213360
    Abstract: Compounds of the formula (I) in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: June 3, 2005
    Publication date: September 13, 2007
    Inventors: Klaus Pekari, Thomas Baer, Mathias Schmidt, Thomas Beckers
  • Novel sulfonylpyrroles
    Publication number: 20070184979
    Abstract: Compounds of the formula I in which the substitutents have the definitions provided in the specification, are novel, effective HDAC inhibitors.
    Type: Application
    Filed: March 10, 2005
    Publication date: August 9, 2007
    Applicant: ALTANA PHARMA AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Petra Gimmnich, Frank Dullweber, Matthias Vennemann