Patents by Inventor Thomas Courtney GARDINIER, II

Thomas Courtney GARDINIER, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Folate receptor targeted nanoparticle drug conjugates and uses thereof
    Patent number: 11957760
    Abstract: The disclosure relates to nanoparticle drug conjugates (NDC) that comprise ultrasmall nanoparticles, folate receptor (FR) targeting ligands, and linker-drug conjugates, and methods of making and using them to treat cancer.
    Type: Grant
    Filed: March 14, 2023
    Date of Patent: April 16, 2024
    Assignee: Elucida Oncology, Inc.
    Inventors: Kai Ma, Aranapakam M. Venkatesan, Feng Chen, Fei Wu, Melik Ziya Türker, Thomas Courtney Gardinier, II, Geno J. Germano, Jr., Gregory Paul Adams, Francis Y. F. Lee
  • Folate receptor targeted nanoparticle drug conjugates and uses thereof
    Patent number: 11744897
    Abstract: The disclosure relates to nanoparticle drug conjugates (NDC) that comprise ultrasmall nanoparticles, folate receptor (FR) targeting ligands, and linker-drug conjugates, and methods of making and using them to treat cancer.
    Type: Grant
    Filed: July 18, 2022
    Date of Patent: September 5, 2023
    Assignee: Elucida Oncology, Inc.
    Inventors: Kai Ma, Aranapakam M. Venkatesan, Feng Chen, Fei Wu, Melik Ziya Türker, Thomas Courtney Gardinier, II, Geno J. Germano, Jr., Gregory Paul Adams, Francis Y. F. Lee
  • FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF
    Publication number: 20230263899
    Abstract: The disclosure relates to nanoparticle drug conjugates (NDC) that comprise ultrasmall nanoparticles, folate receptor (FR) targeting ligands, and linker-drug conjugates, and methods of making and using them to treat cancer.
    Type: Application
    Filed: March 14, 2023
    Publication date: August 24, 2023
    Inventors: Kai MA, Aranapakam M. VENKATESAN, Feng CHEN, Fei WU, Melik Ziya TÜRKER, Thomas Courtney GARDINIER, II, Geno J. GERMANO, Jr., Gregory Paul ADAMS, Francis Y.F. LEE
  • FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF
    Publication number: 20230263898
    Abstract: The disclosure relates to nanoparticle drug conjugates (NDC) that comprise ultrasmall nanoparticles, folate receptor (FR) targeting ligands, and linker-drug conjugates, and methods of making and using them to treat cancer.
    Type: Application
    Filed: March 14, 2023
    Publication date: August 24, 2023
    Inventors: Kai MA, Aranapakam M. VENKATESAN, Feng CHEN, Fei WU, Melik Ziya TÜRKER, Thomas Courtney GARDINIER, II, Geno J. GERMANO, Jr., Gregory Paul ADAMS, Francis Y.F. LEE
  • CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF
    Publication number: 20230241243
    Abstract: The disclosure relates to carrier particle-drug conjugates, including nanoparticle drug conjugates (NDC), that can be used in the delivery of a drug to a biological target (e.g., for targeted delivery of a cytotoxic drug to a cancer cell or tumor). Also disclosed are self-immolative linkers and linker-payload conjugates suitable for use in a carrier particle drug conjugate, and methods of making the same, and methods for treating cancer.
    Type: Application
    Filed: April 7, 2023
    Publication date: August 3, 2023
    Inventors: Aranapakam M. VENKATESAN, Kai MA, Feng CHEN, Fei WU, Melik Ziya TÜRKER, Thomas Courtney GARDINIER, II, Geno J. GERMANO, JR., Gregory Paul ADAMS, Francis Y.F. LEE
  • METHODS OF FUNCTIONALIZING NANOPARTICLES
    Publication number: 20230021059
    Abstract: This disclosure relates to methods of functionalizing a nanoparticle, e.g., for conjugation to a targeting ligand and/or payload moiety, such as for the production of a nanoparticle drug conjugate (NDC).
    Type: Application
    Filed: July 18, 2022
    Publication date: January 19, 2023
    Inventors: Kai MA, Melik Ziya TÜRKER, Fei WU, Feng CHEN, Thomas Courtney GARDINIER, II, Aranapakam M. VENKATESAN, Geno J. GERMANO, JR.
  • FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF
    Publication number: 20220378924
    Abstract: The disclosure relates to nanoparticle drug conjugates (NDC) that comprise ultrasmall nanoparticles, folate receptor (FR) targeting ligands, and linker-drug conjugates, and methods of making and using them to treat cancer.
    Type: Application
    Filed: July 18, 2022
    Publication date: December 1, 2022
    Inventors: Kai MA, Aranapakam M. VENKATESAN, Feng CHEN, Fei WU, Melik Ziya TÜRKER, Thomas Courtney GARDINIER, II, Geno J. GERMANO, Jr., Gregory Paul ADAMS, Francis Y.F. LEE