Patents by Inventor Thomas F. Walsh

Thomas F. Walsh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220372989
    Abstract: An impeller includes a hub, and a plurality of blades supported by the hub, the blades being arranged in at least two blade rows. The impeller has a deployed configuration in which the blades extend away from the hub, and a stored configuration in which at least one of the blades is radially compressed, for example by folding the blade towards the hub. The impeller may also have an operational configuration in which at least some of the blades are deformed from the deployed configuration upon rotation of the impeller when in the deployed configuration. The outer edge of one or more blades may have a winglet, and the base of the blades may have an associated indentation to facilitate folding of the blades.
    Type: Application
    Filed: July 21, 2022
    Publication date: November 24, 2022
    Inventors: Mark W. McBride, Thomas M. Mallison, Gregory P. Dillon, Robert L. Campbell, David A. Boger, Stephen A. Hambric, Robert F. Kunz, James P. Runt, Justin M. Walsh, Boris Leschinsky
  • Patent number: 11434921
    Abstract: An impeller includes a hub, and a plurality of blades supported by the hub, the blades being arranged in at least two blade rows. The impeller has a deployed configuration in which the blades extend away from the hub, and a stored configuration in which at least one of the blades is radially compressed, for example by folding the blade towards the hub. The impeller may also have an operational configuration in which at least some of the blades are deformed from the deployed configuration upon rotation of the impeller when in the deployed configuration. The outer edge of one or more blades may have a winglet, and the base of the blades may have an associated indentation to facilitate folding of the blades.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: September 6, 2022
    Assignees: TC1 LLC, The Penn State Research Foundation
    Inventors: Mark W. McBride, Thomas M. Mallison, Gregory P. Dillon, Robert L. Campbell, David A. Boger, Stephen A. Hambric, Robert F. Kunz, James P. Runt, Justin M. Walsh, Boris Leschinsky
  • Patent number: 11428236
    Abstract: An impeller includes a hub, and a plurality of blades supported by the hub, the blades being arranged in at least two blade rows. The impeller has a deployed configuration in which the blades extend away from the hub, and a stored configuration in which at least one of the blades is radially compressed, for example by folding the blade towards the hub. The impeller may also have an operational configuration in which at least some of the blades are deformed from the deployed configuration upon rotation of the impeller when in the deployed configuration. The outer edge of one or more blades may have a winglet, and the base of the blades may have an associated indentation to facilitate folding of the blades.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: August 30, 2022
    Assignees: TC1 LLC, THE PENN STATE RESEARCH FOUNDATION
    Inventors: Mark W. McBride, Thomas M. Mallison, Gregory P. Dillon, Robert L. Campbell, David A. Boger, Stephen A. Hambric, Robert F. Kunz, James P. Runt, Justin M. Walsh, Boris Leschinsky
  • Patent number: 8757378
    Abstract: A package for a surgical blade tip is provided herein. The package cooperates with the surgical blade tip to properly retain it and facilitate mounting onto a surgical blade handle. In one aspect, the invention includes a package having a body with a side wall and at least two detents extending inwardly from the side wall. In addition, a surgical blade tip is provided having an adaptor with a blade extending therefrom. The adaptor includes at least two recesses formed therein. The surgical blade tip is disposed in the package with the detents being at least partially inserted into the recesses. Also, the detents are configured to apply a retentive force to the adaptor to retain the adaptor in a first position and configured to deflect with a predetermined amount of torque being applied to the surgical blade tip so as to permit the adaptor to rotate from the first position to a second position where the detents are not inserted into the recesses.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: June 24, 2014
    Assignee: Beaver-Visitec International (US), Inc.
    Inventors: Dana Cote, Robert DeMarinis, Gregory P. Halloran, Thomas F. Walsh, Jessica Chiappone
  • Patent number: 8445680
    Abstract: The present invention relates to tetrahydrothienopyridine compounds useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
    Type: Grant
    Filed: February 11, 2009
    Date of Patent: May 21, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: John S. Debenham, Jeffrey J. Hale, Christina B. Madsen-Duggan, Thomas F. Walsh
  • Patent number: 8372863
    Abstract: The present invention relates to tetrahydro-1H-pyrrolo fused pyridone compounds useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
    Type: Grant
    Filed: February 11, 2009
    Date of Patent: February 12, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Matthew J. Clements, Vincent J. Colandrea, John S. Debenham, Jeffrey J. Hale, Christina B. Madsen-Duggan, Thomas F. Walsh
  • Patent number: 8278304
    Abstract: The present invention relates to substituted 4-hydroxypyrimidine-5-carboxamides useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: October 2, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Matthew J. Clements, John S. Debenham, Jeffrey J. Hale, Christina B. Madsen-Duggan, Thomas F. Walsh
  • Patent number: 7999107
    Abstract: Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, Alzheimer's disease, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, Huntington's disease movement disorders, and schizophrenia.
    Type: Grant
    Filed: January 16, 2008
    Date of Patent: August 16, 2011
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: John S. Debenham, Jeffrey J. Hale, Pei Huo, Christina B. Madsen-Duggan, Thomas F. Walsh, Lin Yan
  • Publication number: 20110009406
    Abstract: The present invention relates to tetrahydro-1H-pyrrolo fused pyridone compounds useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
    Type: Application
    Filed: February 11, 2009
    Publication date: January 13, 2011
    Inventors: Matthew J. Clements, Vincent J. Colandrea, John S. Debenham, Jeffrey J. Hale, Christina B. Madsen-Duggan, Thomas F. Walsh
  • Publication number: 20110009425
    Abstract: The present invention relates to tetrahydrothienopyridine compounds useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
    Type: Application
    Filed: February 11, 2009
    Publication date: January 13, 2011
    Inventors: John S. Debenham, Jeffrey J. Hale, Christina B. Madsen-Duggan, Thomas F. Walsh
  • Patent number: 7834062
    Abstract: The present invention relates to Mannich base antimalarial aminoalkylphenol compounds and their use against protozoa of the genus Plasmodium, particularly emerging strains of drug-resistant Plasmodia. This invention further relates to compositions containing such compounds and a process for making the compounds. This and other aspects of the invention are realized upon review of the entire specification.
    Type: Grant
    Filed: August 13, 2009
    Date of Patent: November 16, 2010
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Conrad P. Dorn, Mary Ann Powles, Thomas F. Walsh, Matthew J. Wyvratt
  • Publication number: 20100252467
    Abstract: A package for a surgical blade tip is provided herein. The package cooperates with the surgical blade tip to properly retain it and facilitate mounting onto a surgical blade handle. In one aspect, the invention includes a package having a body with a side wall and at least two detents extending inwardly from the side wall. In addition, a surgical blade tip is provided having an adaptor with a blade extending therefrom. The adaptor includes at least two recesses formed therein. The surgical blade tip is disposed in the package with the detents being at least partially inserted into the recesses. Also, the detents are configured to apply a retentive force to the adaptor to retain the adaptor in a first position and configured to deflect with a predetermined amount of torque being applied to the surgical blade tip so as to permit the adaptor to rotate from the first position to a second position where the detents are not inserted into the recesses.
    Type: Application
    Filed: March 31, 2010
    Publication date: October 7, 2010
    Applicant: BECTON, DICKINSON AND COMPANY
    Inventors: Dana Cote, Robert DeMarinis, Gregory P. Halloran, Thomas F. Walsh, Jessica Chiappone
  • Patent number: 7728141
    Abstract: Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.
    Type: Grant
    Filed: October 29, 2004
    Date of Patent: June 1, 2010
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: John S. Debenham, George A. Doss, Christina B. Madsen-Duggan, Thomas F. Walsh
  • Patent number: 7700778
    Abstract: Certain novel 4-substituted N-acylated piperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: April 20, 2010
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Mark T. Goulet, Ravi P. Nargund, Feroze Ujjainwalla, Thomas F. Walsh, Daniel Warner
  • Publication number: 20100063032
    Abstract: Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, Alzheimer s disease, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson s disease, movement disorders, and schizophrenia.
    Type: Application
    Filed: March 24, 2008
    Publication date: March 11, 2010
    Inventors: John S. Debenham, Christina B. Madsen-Duggan, Thomas F. Walsh
  • Publication number: 20100029697
    Abstract: Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, Alzheimer s disease, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson s disease, movement disorders, and schizophrenia.
    Type: Application
    Filed: March 24, 2008
    Publication date: February 4, 2010
    Inventors: John S. Debenham, Christina B. Madsen-Duggan, Jeffrey J. Hale, Thomas F. Walsh
  • Publication number: 20090298949
    Abstract: The present invention relates to Mannich base antimalarial aminoalkylphenol compounds and their use against protozoa of the genus Plasmodium, particularly emerging strains of drug-resistant Plasmodia. This invention further relates to compositions containing such compounds and a process for making the compounds. This and other aspects of the invention are realized upon review of the entire specification.
    Type: Application
    Filed: August 13, 2009
    Publication date: December 3, 2009
    Inventors: Conrad P. Dorn, Mary Ann Powles, Thomas F. Walsh, Matthew J. Wyvratt
  • Publication number: 20090239876
    Abstract: The present invention relates to substituted 4-hydroxypyrimidine-5-carboxamides useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
    Type: Application
    Filed: March 12, 2009
    Publication date: September 24, 2009
    Inventors: Matthew J. Clements, John S. Debenham, Jeffrey J. Hale, Christian B. Madsen-Duggan, Thomas F. Walsh
  • Patent number: D636082
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: April 12, 2011
    Assignee: Beaver-Visitec International (US), Inc.
    Inventors: Dana Cote, Gregory P. Halloran, Thomas F. Walsh, Jessica Chiappone
  • Patent number: D674687
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: January 22, 2013
    Assignee: Beaver-Visitec International (US), Inc.
    Inventors: Dana Cote, Gregory P. Halloran, Thomas F. Walsh, Jessica Chiappone