Patents by Inventor Thomas Gahm

Thomas Gahm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090196526
    Abstract: A scanning device for biological slides is provided, which can be operated in an interactive routine mode as well as in an unsupervised high speed automatic mode. In the first case, typical components, which the pathologist is used to operating manually, such as the microscope, the stage and the focus, and which have to be motorized for the automatic unsupervised system mode, are configured to simulate manual use, operation, and response. A non-interlaced area scan camera supports the interactive selection and acquisition of individual images in the manual mode, as well as the continuous high-speed scan motion for the rare event detection and virtual slide scan applications of the system. Due to the particular requirements to accommodate both operational modes, methods are described for constructing the virtual slide out of image tiles with varying overlap areas in the x- and y-directions.
    Type: Application
    Filed: March 31, 2009
    Publication date: August 6, 2009
    Inventors: Joachim Helmut Schmid, Thomas Gahm, Kevin Russell Kooy, Rainer Dorrer, Bruno Krief, John Royal Cheeseman
  • Publication number: 20090006969
    Abstract: A slide viewer capable of simultaneous display of more than one representation of an area of interest of a slide is provided. The slide viewer includes a database containing at least two data files representing different representations for a same area of interest on one or multiple correlated slides or at least two different digital presentations of the same representation. The representations are views of different illumination and/or of different contrast. Associated with the database are a processor and a display. The processor retrieves data files representing different representations of the same of area of interest and displays them on the display. A user is allowed to simultaneously view representations of the same area of interest, where the representations are of views different from each other by either illumination and/or contrast or by the digital information content presented, and/or by the information acquired from multiple correlated slides.
    Type: Application
    Filed: June 25, 2008
    Publication date: January 1, 2009
    Inventors: Thomas Gahm, Rainer Dorrer, Joachim Schmid, Ryan Williams
  • Publication number: 20060133657
    Abstract: A scanning device for biological slides is provided, which can be operated in an interactive routine mode as well as in an unsupervised high speed automatic mode. In the first case, typical components, which the pathologist is used to operating manually, such as the microscope, the stage and the focus, and which have to be motorized for the automatic unsupervised system mode, are configured to simulate manual use, operation, and response. A non-interlaced area scan camera supports the interactive selection and acquisition of individual images in the manual mode, as well as the continuous high-speed scan motion for the rare event detection and virtual slide scan applications of the system. Due to the particular requirements to accommodate both operational modes, methods are described for constructing the virtual slide out of image tiles with varying overlap areas in the x- and y-directions.
    Type: Application
    Filed: August 16, 2005
    Publication date: June 22, 2006
    Inventors: Joachim Schmid, Thomas Gahm, Kevin Kooy, Rainer Dorrer, Bruno Krief, John Cheeseman
  • Patent number: 7065236
    Abstract: A method of determining an amount of at least one molecular specie comprising a sample is provided, each molecular specie being indicated by a dye. The amount of the molecular specie is determined from an image of the sample captured as image data by a color image acquisition device in a video-microscopy system. An optical density of the sample is first determined in each of a red, green, and blue channel at a particular pixel in the image. A corresponding optical density matrix is thereafter formed for that pixel. The optical density matrix is then multiplied by the inverse of a relative absorption coefficient matrix so as to form a resultant matrix for the pixel. The relative absorption coefficient matrix comprises a relative absorption coefficient for each dye, independently of the sample, in each of the red, green, and blue channels. The resultant matrix thus comprises the amount of each molecular specie, as indicated by the respective dye, for that pixel.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: June 20, 2006
    Assignee: TriPath Imaging, Inc.
    Inventors: Raphaƫl Marcelpoil, Thomas Gahm
  • Publication number: 20030210262
    Abstract: The present invention provides a slide viewer capable of simultaneous display of more than one scan of an area of interest of a slide. The slide viewer includes a database containing at least two data files representing different scans for a same area of interest on one or multiple correlated slides or at least two different digital presentations of the same scan. The scans are views of different illumination and/or of different contrast. Associated with the database are a processor and a display. The processor retrieves data files representing different scans of the same of area of interest and displays them on the display. The present invention allows a user to simultaneously view scans of the same area of interest, where the scans are of views different from each other by either illumination and/or contrast or by the digital information content presented, and/or by the information acquired from multiple correlated slides.
    Type: Application
    Filed: May 10, 2002
    Publication date: November 13, 2003
    Applicant: TriPath Imaging, Inc.
    Inventors: Thomas Gahm, Rainer Dorrer, Joachim Schmid
  • Publication number: 20030091221
    Abstract: A method of determining an amount of at least one molecular specie comprising a sample is provided, each molecular specie being indicated by a dye. The amount of the molecular specie is determined from an image of the sample captured as image data by a color image acquisition device in a video-microscopy system. An optical density of the sample is first determined in each of a red, green, and blue channel at a particular pixel in the image. A corresponding optical density matrix is thereafter formed for that pixel. The optical density matrix is then multiplied by the inverse of a relative absorption coefficient matrix so as to form a resultant matrix for the pixel. The relative absorption coefficient matrix comprises a relative absorption coefficient for each dye, independently of the sample, in each of the red, green, and blue channels. The resultant matrix thus comprises the amount of each molecular specie, as indicated by the respective dye, for that pixel.
    Type: Application
    Filed: September 19, 2001
    Publication date: May 15, 2003
    Applicant: Tripath Imaging, Inc.
    Inventors: Raphael Marcelpoil, Thomas Gahm