Patents by Inventor Thomas H. Walters

Thomas H. Walters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190195758
    Abstract: In various aspects, the present disclosure pertains to methods of performing a sample enrichment procedure, which comprise: adding a sample fluid that comprises at least one phospholipid and at least one target analyte to a sorbent that comprises a hydrophobic component and a cation exchange component, thereby resulting in sorbent with bound phospholipid and bound target analyte; adding an aqueous solution comprising an acidic compound and a salt; adding an organic solution to the sorbent thereby desorbing at least a portion of the bound phospholipid from the sorbent; and adding an elution solution to the sorbent, thereby desorbing at least a portion of the bound target analyte from the sorbent and forming a solution of the target analyte in the elution solution. In other aspects, the present disclosure pertains to kits, which may be used in conjunction with such methods.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 27, 2019
    Inventors: Bonnie A. Alden, Kenneth Berthelette, Jon Finch, Donna Osterman, Thomas Swann, Thomas H. Walter
  • Publication number: 20190091606
    Abstract: The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for its preparation and separations devices containing the chromatographic material; separations devices, chromatographic columns and kits comprising the same; and methods for the preparation thereof. The chromatographic materials of the invention are high purity chromatographic materials comprising a chromatographic surface wherein the chromatographic surface comprises a hydrophobic surface group and one or more ionizable modifier.
    Type: Application
    Filed: November 28, 2018
    Publication date: March 28, 2019
    Applicant: Waters Technologies Corporation
    Inventors: Kevin D. Wyndham, Pamela C. Iraneta, Thomas H. Walter
  • Patent number: 10159911
    Abstract: The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for its preparation and separations devices containing the chromatographic material; separations devices, chromatographic columns and kits comprising the same; and methods for the preparation thereof. The chromatographic materials of the invention are high purity chromatographic materials comprising a chromatographic surface wherein the chromatographic surface comprises a hydrophobic surface group and one or more ionizable modifier.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: December 25, 2018
    Assignee: Waters Technologies Corporation
    Inventors: Kevin Daniel Wyndham, Pamela C. Iraneta, Thomas H. Walter
  • Patent number: 10150098
    Abstract: The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for its preparation and separations devices containing the chromatographic material; separations devices, chromatographic columns and kits comprising the same; and methods for the preparation thereof.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: December 11, 2018
    Assignee: WATERS TECHNOLOGIES CORPORATION
    Inventors: Kevin D. Wyndham, Pamela C. Iraneta, Thomas H. Walter
  • Publication number: 20180291044
    Abstract: Methods, kits and devices for separating phospholipids and proteins from small molecules in biochemical samples can feature an apparatus having a wetting barrier, at least one frit and a separation media. For example, an apparatus can include at least one wall defining a chamber having an exit and an entrance; a wetting barrier disposed between the exit and entrance, so as to define a separation media space located between the wetting barrier and the exit and a sample receiving area located between the wetting barrier and the entrance; and a separation media disposed adjacent to the wetting barrier and having a specific affinity for phospholipids.
    Type: Application
    Filed: March 30, 2018
    Publication date: October 11, 2018
    Inventors: Pamela C. Iraneta, Thomas H. Walter, Xin Zhang, Daniel P. Walsh, Kevin D. Wyndham, Raymond P. Fisk
  • Patent number: 9951092
    Abstract: Methods, kits and devices for separating phospholipids and proteins from small molecules in biochemical samples can feature an apparatus having a wetting barrier, at least one fit and a separation media. For example, an apparatus can include at least one wall defining a chamber having an exit and an entrance; a wetting barrier disposed between the exit and entrance, so as to define a separation media space located between the wetting barrier and the exit and a sample receiving area located between the wetting barrier and the entrance; and a separation media disposed adjacent to the wetting barrier and having a specific affinity for phospholipids.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: April 24, 2018
    Assignee: Waters Technologies Corporation
    Inventors: Pamela C. Iraneta, Thomas H. Walter, Xin Zhang, Daniel P. Walsh, Kevin D. Wyndham, Raymond P. Fisk
  • Patent number: 9417977
    Abstract: In one embodiment the present invention includes a system for transaction recovery in a distributed computing environment. The system includes a transaction log server, application servers, and resource servers. The transaction log server stores a shared transaction log. The application servers implement a distributed transaction application and accesses the shared transaction log when performing a transaction using the distributed transaction application. The resource servers store data and that operate with the application servers to access the data according to the transaction. If one of the application servers fails, another application server assumes responsibility for a portion of the shared transaction log that was previously accessed by the failed application server.
    Type: Grant
    Filed: December 31, 2008
    Date of Patent: August 16, 2016
    Assignee: SAP SE
    Inventors: Thomas H. Walter, Ralf Kuersch, Nikolai D. Tankov, Peter H. Peshev
  • Patent number: 9089836
    Abstract: Novel materials for chromatographic separations, processes for their preparation, and separation devices containing the chromatographic materials. In particular, the novel materials are porous inorganic/organic hybrid monolith materials, which desirably may be surface modified, and which offer more efficient chromatographic separations than that known in the art.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: July 28, 2015
    Assignee: Waters Technologies Corporation
    Inventors: Thomas H. Walter, Julia Ding, Marianna Kele, John E. O'Gara, Pamela C. Iraneta
  • Patent number: 8845892
    Abstract: Embodiments of the present invention are directed to devices, methods and apparatus for performing separations in which particulates are separated or removed from a fluid stream flowing to a column. In one embodiment directed to a device, the invention includes a body (13) having a first surface (17) and a second surface (19) and at least one wall (23). At least one of the first surface (17) and second surface (19) is for receiving in sealing engagement a first conduit means. The remaining first surface (17) or second surface (19) is for engaging a column or a second conduit (19). The at least one wall (23) extends between the first surface (17) and the second surface (19). The body (13) has at least one opening (25) extending from the first surface (17) to the second surface (19) defining a chamber for receiving a solid phase separation media assembly (15).
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: September 30, 2014
    Assignee: Waters Technologies Corporation
    Inventors: Christopher C. Benevides, Jonathan L. Belanger, Marianna Kele, Thomas H. Walter, Raymond P. Fisk
  • Publication number: 20140284259
    Abstract: Novel material for chromatographic separations, processes for its preparation, and separations devices containing the chromatographic material. In particular, the disclosure describes porous inorganic/organic hybrid particles having a chromatographically-enhancing pore geometry, which desirably may be surface modified, and that offer more efficient chromatographic separations than that known in the art.
    Type: Application
    Filed: June 3, 2014
    Publication date: September 25, 2014
    Applicant: Waters Technologies Corporation
    Inventors: Zhiping Jiang, Raymond P. Fisk, John E. O'Gara, Thomas H. Walter, Kevin D. Wyndham
  • Patent number: 8778453
    Abstract: Novel material for chromatographic separations, processes for its preparation, and separations devices containing the chromatographic material. In particular, the disclosure describes porous inorganic/organic hybrid particles having a chromatographically-enhancing pore geometry, which desirably may be surface modified, and that offer more efficient chromatographic separations than that known in the art.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: July 15, 2014
    Assignee: Waters Technologies Corporation
    Inventors: Zhiping Jiang, Raymond P. Fisk, John E. O'Gara, Thomas H. Walter, Kevin D. Wyndham
  • Publication number: 20130324395
    Abstract: Novel materials for chromatographic separations, processes for their preparation, and separation devices containing the chromatographic materials. In particular, the novel materials are porous inorganic/organic hybrid monolith materials, which desirably may be surface modified, and which offer more efficient chromatographic separations than that known in the art.
    Type: Application
    Filed: March 25, 2013
    Publication date: December 5, 2013
    Applicant: Waters Technologies Corporation
    Inventors: Thomas H. Walter, Julia Ding, Marianna Kele, John E. O'Gara, Pamela C. Iraneta
  • Publication number: 20130319086
    Abstract: The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for its preparation and separations devices containing the chromatographic material; separations devices, chromatographic columns and kits comprising the same; and methods for the preparation thereof. The chromatographic materials of the invention are high purity chromatographic materials comprising a chromatographic surface wherein the chromatographic surface comprises a hydrophobic surface group and one or more ionizable modifier.
    Type: Application
    Filed: January 25, 2013
    Publication date: December 5, 2013
    Applicant: Waters Technologies Corporation
    Inventors: Kevin Daniel Wyndham, Pamela C. Iraneta, Thomas H. Walter
  • Publication number: 20130135610
    Abstract: The present invention is directed to a device and a method for performing size exclusion chromatography. Embodiments of the present invention feature devices and methods for size exclusion chromatography at normal high performance liquid chromatography or ultra performance liquid chromatography pressures and above using small particles.
    Type: Application
    Filed: December 15, 2010
    Publication date: May 30, 2013
    Applicant: Waters Technologies Corporation
    Inventors: Edouard S.P. Bouvier, Kevin D. Wyndham, Thomas H. Walter, Lynda Neue
  • Patent number: 8404346
    Abstract: Novel materials for chromatographic separations, processes for their preparation, and separation devices containing the chromatographic materials. In particular, the novel materials are porous inorganic/organic hybrid monolith materials, which desirably may be surface modified, and which offer more efficient chromatographic separations than that known in the art.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: March 26, 2013
    Assignee: Waters Technologies Corporation
    Inventors: Thomas H. Walter, Julia Ding, Marianna Kele, John E. O'Gara, Pamela C. Iraneta
  • Publication number: 20130053588
    Abstract: Methods, kits and devices for separating phospholipids and proteins from small molecules in biochemical samples can feature an apparatus having a wetting barrier, at least one fit and a separation media. For example, an apparatus can include at least one wall defining a chamber having an exit and an entrance; a wetting barrier disposed between the exit and entrance, so as to define a separation media space located between the wetting barrier and the exit and a sample receiving area located between the wetting barrier and the entrance; and a separation media disposed adjacent to the wetting barrier and having a specific affinity for phospholipids.
    Type: Application
    Filed: May 20, 2011
    Publication date: February 28, 2013
    Applicant: Waters Technologies Corporation
    Inventors: Pamela C. Iraneta, Thomas H. Walter, Xin Zhang, Daniel P. Walsh, Kevin D. Wyndham, Raymond P. Fish
  • Publication number: 20120273404
    Abstract: The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for its preparation and separations devices containing the chromatographic material; separations devices, chromatographic columns and kits comprising the same; and methods for the preparation thereof.
    Type: Application
    Filed: August 4, 2010
    Publication date: November 1, 2012
    Applicant: WATERS TECHNOLOGIES CORPORATION
    Inventors: Kevin D. Wyndham, Pamela C. Iraneta, Thomas H. Walter
  • Patent number: 7919177
    Abstract: Novel material for chromatographic separations, processes for its preparation, and separations devices containing the chromatographic material. In particular, the disclosure describes porous inorganic/organic hybrid particles having a chromatographically-enhancing pore geometry, which desirably may be surface modified, and that offer more efficient chromatographic separations than that known in the art.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: April 5, 2011
    Assignee: Waters Technologies Corporation
    Inventors: Zhiping Jiang, Raymond P. Fisk, John E. O'Gara, Thomas H. Walter, Kevin D. Wyndham
  • Publication number: 20100169284
    Abstract: In one embodiment the present invention includes a system for transaction recovery in a distributed computing environment. The system includes a transaction log server, application servers, and resource servers. The transaction log server stores a shared transaction log. The application servers implement a distributed transaction application and accesses the shared transaction log when performing a transaction using the distributed transaction application. The resource servers store data and that operate with the application servers to access the data according to the transaction. If one of the application servers fails, another application server assumes responsibility for a portion of the shared transaction log that was previously accessed by the failed application server.
    Type: Application
    Filed: December 31, 2008
    Publication date: July 1, 2010
    Applicant: SAP AG
    Inventors: Thomas H. Walter, Ralf Kuersch, Nikolai D. Tankov, Peter H. Peshev
  • Patent number: 7610148
    Abstract: Methods and Systems are provided for interfacing to navigation operations. An application programming interface (API) library is provided having navigation modules, guidance modules, routing modules, and mapping modules. The API is accessible to customized modules operating on a portable electronic device. The customized modules are operable to selectively access and process a number of the modules using the API library while the customized modules are processing on the portable electronic device.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: October 27, 2009
    Assignee: Garmin Ltd.
    Inventors: Thomas H. Walters, Cliff A. Pemble