Patents by Inventor Thomas J. Burke

Thomas J. Burke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9732724
    Abstract: A reciprocating fluid-energy device to be used in a flowing fluid, having a foil, an upstream support member, a downstream support member, and a frame, where the frame retains the device in place within the flowing fluid, the support members movably attach the foil to the frame, and the foil moves laterally back and forth across the direction of the flow of the fluid, with changes in direction of the movement of the foil occurring automatically and spontaneously without external intervention other than the force of the flowing fluid.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: August 15, 2017
    Inventor: Thomas J. Burke
  • Patent number: 9707134
    Abstract: An easily applied and replaced flexible container pouch applied to the penis end and including a restricted opening collar to grasp the penis shaft. The container pouch comprises a plurality of walls having a fluid absorbent layer between at least 2 walls, the inner wall (proximal to the penis) include apertures allowing the fluid emitted by the penis to be received into the absorbent layer(s). In one embodiment, the inner layer(s) comprise fluid barriers (e.g. fluid impermeable or a thick member providing a mechanical spacing) between the fluid-filled absorbent layer(s) and the penis. The resulting device provides comfort and protection from unnecessary fluid immersion and ease of use, application and replacement.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: July 18, 2017
    Inventors: Thomas J. Burke, Jack V. Fullman
  • Publication number: 20160281063
    Abstract: Methods for producing engineered induced pluripotent stem (iPS) cells are provided comprising introducing a first nucleic acid into somatic cells for integration into their genome and reprogramming the cells to produce engineered iPS cells having the nucleic acid integrated into their genome. For example, in certain aspects the cells are reprogrammed by introduction of a genetic element that expresses one or more reprogramming factor and culturing of the cells under conditions sufficient to produce reprogrammed cells.
    Type: Application
    Filed: February 23, 2016
    Publication date: September 29, 2016
    Applicant: Cellular Dynamics International, Inc.
    Inventors: Thomas J. BURKE, Michael MILLER, Michael McLACHLAN, Sarah Jane DICKERSON, Anne STROUSE
  • Patent number: 8733860
    Abstract: A storage system comprising a plurality of shelf units movable together through a circuit attached to and moved by a flexible drive such as a chain or belt, while being guided and stabilized in orientation by a separate guide track which track followers, retained by each shelf unit, move to maintain a selected orientation of the shelves within a system support or enclosure. Each shelf unit is removable by the user from engagement of the drive and from the system enclosure permitting replacement of the shelves within the storage system without system disassembly.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: May 27, 2014
    Inventors: Thomas J. Burke, Ross Marrone, John Skurzynski
  • Publication number: 20130040302
    Abstract: Methods for producing engineered induced pluripotent stem (iPS) cells are provided comprising introducing a first nucleic acid into somatic cells for integration into their genome and reprogramming the cells to produce engineered iPS cells having the nucleic acid integrated into their genome. For example, in certain aspects the cells are reprogrammed by introduction of a genetic element that expresses one or more reprogramming factor and culturing of the cells under conditions sufficient to produce reprogrammed cells.
    Type: Application
    Filed: July 11, 2012
    Publication date: February 14, 2013
    Inventors: Thomas J. Burke, Michael Miller, Michael McLachlan, Sarah Jane Dickerson, Anne Strouse
  • Patent number: 8251964
    Abstract: The present invention provides a sanitary device having a significant capacity (e.g. 30 c.c.) in an plastic pouch (or envelope) gently attached to the end of the male member by releasable pressure sensitive adhesive across an opening which receives the male member. The pressure sensitive adhesive provides close connection to the skin, provides a fluid closure around the male member, and permits closure with opposing adhesive surfaces of the sanitary device not used to surround the circumference of the inserted male member. A further feature provides flaps, tabs or margins at the sanitary device opening which are foldable over the adhesive to selectably cover some portion or all of the adhesive as may be desired by the wearer.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: August 28, 2012
    Inventor: Thomas J. Burke
  • Patent number: 8149138
    Abstract: A manually operated traffic barrier gate which may economically installed and maintained, and easily operated by a single individual during emergency or other critical situations. One embodiment comprises a permanently mounted barrier gate movable from a retracted, upright position to lowered position extended to bridge a preselected traffic path, wherein the gate is counterbalanced to stay in the upright position until deployed, and to be balanced to stay in the deployed state when extended. The barrier gate are operable by one person and includes locking devices to maintain their stored upright or deployed lowered position. A further embodiment of the present invention provides a dual mobile gate which may be towed singly or in a chain (dual gate one behind the other), in a retracted length to the desired location, and thereafter be disconnected from the towing vehicle and left at the site to be deployed in an extended manner or retracted and moved as needed.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: April 3, 2012
    Assignee: Safe-Crossings, L.L.C.
    Inventors: Thomas J. Burke, John Dinunzi
  • Publication number: 20110287973
    Abstract: The present invention relates to novel methods for the quantitative detection of molecules in an array. In particular, the present invention relates to methods and apparatuses for producing a frameless array. In another embodiment, the present invention relates to a composition comprising nitrocellulose that is useful of producing a frameless array. In another embodiment, the present invention relates to a method for detecting a molecular interaction. In yet another embodiment, the present invention relates to kits useful for practicing the methods and apparatuses of the present invention. The present invention provides improved methods and apparatuses for the high throughput analysis of molecular interactions and quantitative detection.
    Type: Application
    Filed: August 5, 2011
    Publication date: November 24, 2011
    Applicant: PRIMORIGEN BIOSCIENCES, LLC
    Inventors: Thomas J. Burke, William L. Patterson, Tobias C. Zutz
  • Patent number: 7533494
    Abstract: A railroad grade crossing assembly including a programmable controller. In a preferred embodiment, the crossing assembly includes at least one camera for the purpose of visually monitoring the crossing assembly and/or the area around the assembly. In another preferred embodiment, the crossing assembly includes a communication link for remotely monitoring and/or controlling the assembly.
    Type: Grant
    Filed: July 21, 2003
    Date of Patent: May 19, 2009
    Inventor: Thomas J. Burke
  • Publication number: 20090111709
    Abstract: The present invention relates to novel methods of the quantitative detection of molecules in an array. In particular, the present invention relates to methods for molecular detection assays performed on solid surfaces. The present invention provides improved methods for the high throughput analysis of molecular interactions and quantitative detection. In another aspect, the invention relates to a method of measuring protein interactions on a solid surface that is useful for the determination of equilibrium binding and rate constants. In yet another aspect, the invention relates to predicting a molecules utility in a detection assay.
    Type: Application
    Filed: October 29, 2008
    Publication date: April 30, 2009
    Inventors: Thomas J. Burke, Tobias C. Zutz, Randall J. Wagner
  • Publication number: 20090075837
    Abstract: The present invention relates to novel methods for the quantitative detection of molecules in an array. In particular, the present invention relates to methods and apparatuses for producing a frameless array. In another embodiment, the present invention relates to a composition comprising nitrocellulose that is useful of producing a frameless array. In another embodiment, the present invention relates to a method for detecting a molecular interaction. In yet another embodiment, the present invention relates to kits useful for practicing the methods and apparatuses of the present invention. The present invention provides improved methods and apparatuses for the high throughput analysis of molecular interactions and quantitative detection.
    Type: Application
    Filed: September 18, 2008
    Publication date: March 19, 2009
    Applicant: PRIMORIGEN BIOSCIENCES, LLC
    Inventors: Thomas J. Burke, William L. Patterson, Tobias C. Zutz
  • Patent number: 7384017
    Abstract: A retractable gate comprising a movable arm gate having multiple sections which nest or telescope into each other when parked (e.g. upright), and extends into a full length blocking position as it is deployed. The gate arm sections are deployed by the movement of one of the arms, e.g. the outer one section, relative to the ground or a stationary support member and is joined to the stationary support member by a pivot point or bearing, and is connected to the stationary support or ground by a cable connection (or equivalent) which powers the arm sections into extended or retracted positions by movement of the gate about the pivot bearing. A novel corresponding counterweight system provides selectable balance and torque requirements.
    Type: Grant
    Filed: June 13, 2005
    Date of Patent: June 10, 2008
    Assignee: Safe-Crossings, LLC
    Inventors: Thomas J. Burke, John Dinunzi
  • Patent number: 7356966
    Abstract: An articulate railroad grade crossing assembly. In a preferred embodiment, the crossing assembly has an adjustable reach so that it can be adjusted to completely or partially close roadways of various sizes. In another preferred embodiment, the assembly includes one or more sensors for detecting the presence of people and/or objects in the crossing area so that the assembly can automatically respond to such presence.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: April 15, 2008
    Inventor: Thomas J. Burke
  • Patent number: 6991552
    Abstract: An overswing alerting mechanism/swing monitoring device that a user can wear, for example on the wrist, hand or arm, that can determine swing formation, and that can display and/or store the determined swing information. As an option, the device includes a visual and/or audible indicator for alerting the user to an improper swinging motion.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: January 31, 2006
    Inventor: Thomas J. Burke
  • Patent number: 6825828
    Abstract: An exemplary embodiment of the invention is a backlit liquid crystal display (LCD) monitor comprising a backlight assembly, a cooling assembly, a rear cover assembly and a controller. The controller monitors temperature and controls cooling accordingly. The controller also monitors bulb luminance and adjusts bulb current accordingly. Faults are monitored and logged so that predictive repair before failure analysis may be performed.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: November 30, 2004
    Assignee: General Digital Corporation
    Inventors: Thomas J. Burke, Gary Elco, Bryan Gudrian
  • Publication number: 20040088923
    Abstract: A railroad grade crossing assembly including a programmable controller. In a preferred embodiment, the crossing assembly includes at least one camera for the purpose of visually monitoring the crossing assembly and/or the area around the assembly. In another preferred embodiment, the crossing assembly includes a communication link for remotely monitoring and/or controlling the assembly.
    Type: Application
    Filed: July 21, 2003
    Publication date: May 13, 2004
    Inventor: Thomas J. Burke
  • Patent number: 6692344
    Abstract: An apparatus and method for cleaning fecal matter from the interior of an extracted animal intestine is disclosed. The apparatus has a horizontal tube member for supporting an intestine; support members attached to opposite sides of the tube member for supporting the side portions of a slit intestine; a transporter mounted below and adjacent to the bottom side of the tube for moving intestines from adjacent the distal end of the tube towards the proximal end; a cutting blade mounted above the tube member; and a plurality of nozzles arranged at transversely opposite sides of the tube member for directing fluid downwardly and about the top side of the pipe member. A method for cleaning animal intestines using such an apparatus is also disclosed.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: February 17, 2004
    Assignee: M & P Chitlin Co., Inc.
    Inventor: Thomas J. Burke
  • Publication number: 20030224469
    Abstract: The invention relates to use of compounds labeled with multiple, spectrally distinct fluorophores in assays that utilize fluorescent polarization to determine if those compounds bind to a binding partner and in assays to determine if those compounds are incorporated into a larger molecule or degraded into smaller components. Fluorescence polarization in such assays is measured at multiple wavelengths corresponding to the wavelengths at which each fluorophore absorbs and emits light. This overcomes any potential interference at a particular wavelength that may be caused by other components in the assay.
    Type: Application
    Filed: June 3, 2002
    Publication date: December 4, 2003
    Inventors: Tonia J. Buchholz, Thomas J. Burke
  • Patent number: 6618993
    Abstract: A railroad grade crossing assembly for blocking vehicle access across a railroad crossing including a gate assembly connectable to a stanchion and light assembly. This gate assembly is movable between a generally upright position to permit vehicle access across a railroad crossing and a generally horizontal position for blocking vehicle access across the railroad crossing. The gate assembly further includes a telescopic arm assembly for completely closing vehicle access to the railroad crossing. In another embodiment of the invention, the railroad grade crossing assembly includes a gate movable between a generally horizontal retracted position to permit vehicle access across a railroad crossing and a generally extended horizontal position for blocking vehicle access across a railroad crossing, the gate includes a telescopic arm for completely closing the railroad crossing, a first and second stanchions.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: September 16, 2003
    Inventor: Thomas J. Burke
  • Publication number: 20030044789
    Abstract: A rapid fluorescence polarization immunoassay (FPIA) for accurate quantification of any protein carrying an N-terminal polypeptide affinity tag especially a polyhistidine affinity tag (HisTag).
    Type: Application
    Filed: June 6, 2001
    Publication date: March 6, 2003
    Inventors: Thomas J. Burke, Robert Lowery, Karen Kleman-Leyer