Patents by Inventor Thomas J. Magliery

Thomas J. Magliery has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF NOTCH SIGNALING AND METHODS OF USE THEREOF
    Publication number: 20240018213
    Abstract: Described herein are Notch-modulating peptides (including monomers and multimers) capable of increasing or decreasing an immune response in a subject, compositions comprising the peptides, and methods of use thereof.
    Type: Application
    Filed: February 10, 2023
    Publication date: January 18, 2024
    Inventors: Thomas J. MAGLIERY, Mikhail M. DIKOV, David CARBONE, Nicholas LONG, Brandon SULLIVAN, Elena TCHEKNEVA
  • Methods and compositions related to antibody fragments that bind to tumor-associated glycoprotein 72 (TAG-72)
    Patent number: 11787872
    Abstract: Disclosed herein are methods and compositions related to antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: October 17, 2023
    Assignee: Ohio State Innovation Foundation
    Inventors: Thomas J. Magliery, Brandon J. Sullivan, Nicholas E. Long
  • Modulators of notch signaling and methods of use thereof
    Patent number: 11613567
    Abstract: Described herein are Notch-modulating peptides (including monomers and multimers) capable of increasing or decreasing an immune response in a subject, compositions comprising the peptides, and methods of use thereof.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: March 28, 2023
    Assignee: Ohio State Innovation Foundation
    Inventors: Thomas J. Magliery, Mikhail M. Dikov, David Carbone, Nicholas Long, Brandon Sullivan, Elena Tchekneva
  • Methods and compositions related to single chain antibody fragments that bind to tumor-associated glycoprotein 72 (TAG-72)
    Patent number: 10919979
    Abstract: Disclosed herein are methods and compositions related to single chain antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: February 16, 2021
    Assignee: Ohio State Innovation Foundation
    Inventors: Thomas J. Magliery, Brandon J. Sullivan, Heather C. Allen, Edward W. Martin, Charles L. Hitchcock, E. David Alten, Nicholas E. Long
  • MODULATORS OF NOTCH SIGNALING AND METHODS OF USE THEREOF
    Publication number: 20200277354
    Abstract: Described herein are Notch-modulating peptides (including monomers and multimers) capable of increasing or decreasing an immune response in a subject, compositions comprising the peptides, and methods of use thereof.
    Type: Application
    Filed: March 26, 2018
    Publication date: September 3, 2020
    Inventors: Thomas J. MAGLIERY, Mikhail M. DIKOV, David CARBONE, Nicholas LONG, Brandon SULLIVAN, Elena TCHEKNEVA
  • METHODS AND COMPOSITIONS RELATED TO ANTIBODY FRAGMENTS THAT BIND TO TUMOR-ASSOCIATED GLYCOPROTEIN 72 (TAG-72)
    Publication number: 20200255538
    Abstract: Disclosed herein are methods and compositions related to antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).
    Type: Application
    Filed: November 25, 2019
    Publication date: August 13, 2020
    Inventors: Thomas J. Magliery, Brandon J. Sullivan, Nicholas E. Long
  • Methods and compositions related to antibody fragments that bind to tumor-associated glycoprotein 72 (TAG-72)
    Patent number: 10487151
    Abstract: Disclosed herein are methods and compositions related to antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: November 26, 2019
    Assignee: Ohio State Innovation Foundation
    Inventors: Thomas J. Magliery, Brandon J. Sullivan, Nicholas E. Long
  • METHODS AND COMPOSITIONS RELATED TO SINGLE CHAIN ANTIBODY FRAGMENTS THAT BIND TO TUMOR-ASSOCIATED GLYCOPROTEIN 72 (TAG-72)
    Publication number: 20180037663
    Abstract: Disclosed herein are methods and compositions related to single chain antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).
    Type: Application
    Filed: July 31, 2017
    Publication date: February 8, 2018
    Inventors: Thomas J. Magliery, Brandon J. Sullivan, Heather C. Allen, Edward W. Martin, Charles L. Hitchcock, E. David Alten, Nicholas E. Long
  • METHODS AND COMPOSITIONS RELATED TO ANTIBODY FRAGMENTS THAT BIND TO TUMOR-ASSOCIATED GLYCOPROTEIN 72 (TAG-72)
    Publication number: 20170218081
    Abstract: Disclosed herein are methods and compositions related to antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).
    Type: Application
    Filed: July 23, 2015
    Publication date: August 3, 2017
    Inventors: Thomas J. Magliery, Brandon J. Sullivan, Nicholas E. Long
  • Methods and compositions related to single chain antibody fragments that bind to tumor-associated glycoprotein 72 (TAG-72)
    Patent number: 9718888
    Abstract: Disclosed herein are methods and compositions related to single chain antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: August 1, 2017
    Assignee: Ohio State Innovation Foundation
    Inventors: Thomas J. Magliery, Brandon J. Sullivan, Heather C. Allen, Edward W. Martin, Charles L. Hitchcock, E. David Alten, Nicholas E. Long
  • METHODS AND COMPOSITIONS RELATED TO SINGLE CHAIN ANTIBODY FRAGMENTS THAT BIND TO TUMOR-ASSOCIATED GLYCOPROTEIN 72 (TAG-72)
    Publication number: 20160176979
    Abstract: Disclosed herein are methods and compositions related to single chain antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).
    Type: Application
    Filed: July 23, 2014
    Publication date: June 23, 2016
    Inventors: Thomas J. Magliery, Brandon J. Sullivan, Heather C. Allen, Edward W. Martin, Charles L. Hitchcock, E. David Alten, Nicholas E. Long
  • Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs
    Patent number: 9163271
    Abstract: This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: October 20, 2015
    Assignees: The Scripps Research Instiute, The Regents of the University of California
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason W. Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Stephen William Santoro, Zhiwen Zhang
  • Methods and Compositions for the Production of Orthogonal tRNA-Aminoacyl tRNA Synthetase Pairs
    Publication number: 20130309720
    Abstract: This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.
    Type: Application
    Filed: May 18, 2012
    Publication date: November 21, 2013
    Applicants: The Regents of the University of California, The Scripps Research Institute
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason W. Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Stephen William Santoro, Zhiwen Zhang
  • IN Vivo Incorporation of Unnatural Amino Acids
    Publication number: 20120202243
    Abstract: The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
    Type: Application
    Filed: August 2, 2011
    Publication date: August 9, 2012
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE SCRIPPS RESEARCH INSTITUTE
    Inventors: PETER G. SCHULTZ, LEI WANG, JOHN CHRISTOPHER ANDERSON, JASON WILLIAM CHIN, DAVID R. LIU, THOMAS J. MAGLIERY, ERIC L. MEGGERS, RYAN A. MEHL, MIRO PASTRNAK, STEPHEN WILLIAM SANTORO, ZHIWEN ZHANG
  • Methods and composition for the production of orthogonal tRNA-aminoacyltRNA synthetase pairs
    Patent number: 8183012
    Abstract: This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: May 22, 2012
    Assignees: The Scripps Research Institute, The Regents of the University of California
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Steven William Santoro, Zhiwen Zhang
  • Methods and composition for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs
    Patent number: 8173364
    Abstract: This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: May 8, 2012
    Assignees: The Scripps Research Institute, The Regents of the University of California
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason W. Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Stephen William Santoro, Zhiwen Zhang
  • In vivo incorporation of unnatural amino acids
    Patent number: 8173392
    Abstract: The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: May 8, 2012
    Assignees: The Scripps Research Institute, The Regents of the University of California
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason W. Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Stephen William Santoro, Zhiwen Zhang
  • Methods and Compositions for the Production of Orthogonal tRNA-Aminoacyl tRNA Synthetase Pairs
    Publication number: 20120101006
    Abstract: This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.
    Type: Application
    Filed: June 15, 2011
    Publication date: April 26, 2012
    Applicants: The Regents of the University of California, The Scripps Research Institute
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason W. Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Stephen William Santoro, Zhiwen Zhang
  • In vivo incorporation of unnatural amino acids
    Patent number: 8114648
    Abstract: The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: February 14, 2012
    Assignees: The Scripps Research Institute, The Regents of the University of California
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason W. Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Stephen William Santoro, Zhiwen Zhang
  • In vivo incorporation of unnatural amino acids
    Patent number: 8030074
    Abstract: The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: October 4, 2011
    Assignees: The Scripps Research Institute, The Regents of the University of California
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason W. Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Stephen William Santoro, Zhiwen Zhang