Patents by Inventor Thomas M. Niemczyk

Thomas M. Niemczyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optical method for measuring an analyte using area-modulated luminescence
    Patent number: 5190857
    Abstract: A luminescence measuring system is provided for detecting luminescence at extremely low concentrations of luminescing moieties. The method employs alternating radiation at a plurality of loci of an inhomogenous solution, where the radiant power is maintained constant, and the irradiated volumes of pairs of loci are systematically varied. With the probability being very low that the same luminescence signal will be obtained in the two or more measurements, by comparing the measurements, one can detect a low luminescence signal in the presence of relatively high noise levels. Various techniques are described for modulating the irradiance and detecting changes in signal.
    Type: Grant
    Filed: June 5, 1991
    Date of Patent: March 2, 1993
    Assignee: Acrogen, Inc.
    Inventors: Fritz S. Allen, Carlos Bustamante, Thomas M. Niemczyk, Burton P. Dorman
  • Area-modulated luminescence (AML)
    Patent number: 5026159
    Abstract: A luminescence measuring system is provided for detecting luminescence at extremely low concentrations of luminescing moieties. The method employs alternating radiation at a plurality of loci of an inhomogenous solution, where the radiant power is maintained constant, and the irradiated volumes of pairs of loci are systematically varied. With the probability being very low that the same luminescence signal will be obtained in the two or more measurements, by comparing the measurements, one can detect a low luminescence signal in the presence of relatively high noise levels. Various techniques are described for modulating the irradiance and detecting changes in signal.
    Type: Grant
    Filed: May 19, 1989
    Date of Patent: June 25, 1991
    Assignee: Acrogen, Inc.
    Inventors: Fritz S. Allen, Carlos Bustamante, Thomas M. Niemczyk, Burton P. Dorman