Patents by Inventor Thomas P. Nigra

Thomas P. Nigra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Compositions for Treating 5Alpha-Reductase Type 1 and Type 2 Dependent Conditions
    Publication number: 20080207545
    Abstract: The invention relates generally to the use of anti-sense oligonucleotides, small interfering RNA, and ribozymes to modulate expression of the human steroid 5?-reductase gene and thereby modulate levels of dihydrotestosterone (DHT). Elevated levels of DHT are associated with various disorders including, but not limited to, skin diseases, hair loss, hirsuitism, and benign prostatic hyperplasia.
    Type: Application
    Filed: October 20, 2004
    Publication date: August 28, 2008
    Inventors: Glenn D. Hoke, Thomas P. Nigra
  • Topical drug delivery composition and method
    Patent number: 6586473
    Abstract: A topical composition for delivering an effective amount of a pharmaceutically acceptable drug, including laureth-4, propylene glycol, dimethylsorbide, and a pharmaceutically acceptable diluent is described as an improved drug delivery composition. Further, a method of transepithelial delivery of a drug to a human by topical application to the skin of a human of a composition including laureth-4, propylene glycol, dimethylsorbide, a pharmaceutically acceptable diluent of water and ethanol and an effective amount of a pharmaceutically acceptable drug has beneficial delivery effects.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: July 1, 2003
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Thomas P. Nigra, Eugene H. Gans
  • Topical drug delivery composition and method
    Patent number: 6028105
    Abstract: A topical composition for delivering an effective amount of a pharmaceutically acceptable drug, including laureth-4, propylene glycol, dimethylsorbide, and a pharmaceutically acceptable diluent is described as an improved drug delivery composition. Further, a method of transepithelial delivery of a drug to a human by topical application to the skin of a human of a composition including laureth-4, propylene glycol, dimethylsorbide, a pharmaceutically acceptable diluent of water and ethanol and an effective amount of a pharmaceutically acceptable drug has beneficial delivery effects.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 22, 2000
    Inventor: Thomas P. Nigra