Patents by Inventor Thomas W. Myers

Thomas W. Myers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160319255
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 3, 2016
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers, Nancy J. Schoenbrunner, Joseph San Filippo
  • DNA polymerases with improved activity
    Patent number: 9441269
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: September 13, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Thomas W. Myers, Shawn Suko
  • DNA polymerases with improved activity
    Patent number: 9428782
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: August 30, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Thomas W. Myers, Shawn Suko
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160230153
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: April 25, 2016
    Publication date: August 11, 2016
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160230152
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: April 25, 2016
    Publication date: August 11, 2016
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • Generic PCR
    Publication number: 20160230208
    Abstract: The present invention provides a method for the amplification of at least a first and a second target nucleic acid that may be present in a fluid sample. The invention further provides a kit and an analytical system for carrying out said amplification.
    Type: Application
    Filed: September 30, 2015
    Publication date: August 11, 2016
    Inventors: Meike Eickhoff, Niclas Hitziger, Anke Mussmann, Thomas W. Myers, Christopher Newhouse, Nicholas Newton, John Niemiec, Nancy Schoenbrunner, Edward S. Smith, Stephen Will, Heike Wilts, Dirk Zimmerman
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160230154
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: April 25, 2016
    Publication date: August 11, 2016
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9410174
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: August 9, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers, Nancy J. Schoenbrunner, Joseph San Filippo
  • Suppression of Non-Specific Amplification with High-Homology Oligonucleotides
    Publication number: 20160208321
    Abstract: The invention comprises suppressor oligonucleotides for reducing amplification of a non-target nucleic acid sequences; the method of designing and using such oligonucleotides, as well as kits and reaction mixtures.
    Type: Application
    Filed: December 22, 2015
    Publication date: July 21, 2016
    Inventors: Xiaoying Chen, Suzanne Cheng, Thomas W. Myers, Nancy Patten, Nancy Schoenbrunner, Sim C. Truong
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160160192
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 9, 2016
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160160190
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 9, 2016
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160160191
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 9, 2016
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160152958
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: February 5, 2016
    Publication date: June 2, 2016
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9353403
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: May 31, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9353402
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: May 31, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160137992
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: January 15, 2016
    Publication date: May 19, 2016
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20160137991
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: January 15, 2016
    Publication date: May 19, 2016
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9340827
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: May 17, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9290747
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: March 22, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9284542
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: March 15, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers