Abstract: Gear mechanism, in particular coaxial gear mechanism or linear gear mechanism, having a toothing system, a tooth carrier with radially oriented guides, teeth which are received in the guides for engagement with the toothing system, the teeth being mounted in the guides such that they can be displaced radially relative to the tooth carrier in the direction of their longitudinal axis, a cam disk for radially driving the teeth, the tooth carrier comprising a first tooth carrier part and a second tooth carrier part.

Abstract: Methods for the diagnosis of leukemias, and more specifically AML, such as MLL-AF9 AML, in a subject, based on the assessment of the expression or activity of one or more of the genes listed in Tables 1 and 2 are disclosed. The use of antibodies or antigen-binding fragments thereof that bind to one or more of proteins showing preferential expression at the cell surface of AML leukemic cells for treating AML is also disclosed.

Abstract: The present disclosure relates to a sensor element for a potentiometric sensor including a substrate, and a potentiometric sensor layer disposed on the substrate, wherein the substrate includes at least one region electrically conductively connected to the sensor layer, and wherein at least the region of the substrate electrically conductively connected to the sensor layer is a mixed-conducting ceramic.

Abstract: According to at least one aspect of the present disclosure, a method for determining orthophosphate content of a liquid, comprising: registering a first measurement signal of an ion selective dihydrogen phosphate sensor; registering a second measurement signal of an ion selective hydrogen phosphate sensor; and determining the orthophosphate content of the liquid based on the first and second measurement signals. The dihydrogen phosphate sensor can comprise an ion selective dihydrogen phosphate electrode and the hydrogen phosphate sensor an ion selective hydrogen phosphate electrode. In the step of determining the orthophosphate content of the liquid, a cross-sensitivity of the dihydrogen phosphate electrode to hydrogen phosphate present in the liquid and a cross-sensitivity of the hydrogen phosphate electrode to dihydrogen phosphate present in the liquid can be taken into consideration.

Abstract: The present disclosure relates to a glass electrode including an analyte-sensitive glass membrane, an electrically conductive lead, and an intermediate layer which conductively connects the lead and the glass membrane to one another. According to the present disclosure, the intermediate layer is made of an electron- and/or ion-conducting polymer.

Abstract: The present disclosure relates to a measuring probe for electrochemical measurements, including a probe housing having a first cavity to hold a first electrolyte, a first electrode disposed in the first cavity and contacting the first electrolyte, a first junction disposed in a wall of the probe housing, the junction at least temporarily connecting the first cavity with an environment of the measuring probe, a second cavity formed in the probe housing to hold a second electrolyte, a second electrode disposed in the second cavity and contacting the second electrolyte, and a second junction having reversible open and closed states, in which in the closed state the second junction separates the first cavity and the second cavity and in the open state connects the second cavity to the first cavity, thereby enabling a current flow between the first electrolyte and the second electrolyte, mediated via ions as charge carriers therebetween.

Abstract: A half-cell for measuring a pH value of a measuring medium is disclosed including a tube-shaped carrier element and a pH-sensitive glass membrane connected to an end section of the carrier element. At least the end section of the carrier element includes a zirconia-containing and/or alumina-containing ceramic. A method for manufacturing a half-cell for pH value measurement and a potentiometric sensor are further disclosed.

Abstract: A method for determining orthophosphate content of a liquid, comprising: registering a first measurement signal (ISE1) of an ion selective dihydrogen phosphate sensor; registering a second measurement signal (ISE2) of an ion selective hydrogen phosphate sensor; and determining the orthophosphate content of the liquid based on the first (ISE1) and second (ISE2) measurement signals. The dihydrogen phosphate sensor can comprise an ion selective dihydrogen phosphate electrode and the hydrogen phosphate sensor an ion selective hydrogen phosphate electrode. In the step of determining the orthophosphate content of the liquid, a cross-sensitivity of the dihydrogen phosphate electrode to hydrogen phosphate present in the liquid and a cross-sensitivity of the hydrogen phosphate electrode to dihydrogen phosphate present in the liquid can be taken into consideration.

Abstract: Welding tongs (1), especially X-welding tongs (1) for resistance spot welding, with a first tong arm (11), a second tong arm (12), and a drive unit (2) comprising a motor (4) and a gearing (6) for rotating the first tong arm (11) relative to the second tong arm (12) about an axis of rotation (14) of the welding tongs (1), wherein the motor (4) and the gearing (6) are arranged coaxially and the second tong arm (12) is fastened to the housing in an abutment plane (29), which is situated on the motor side of an outer driven bearing plane of the drive unit (2).

Abstract: The present disclosure includes to a sensor element including a membrane having a first functionalized region and a second functionalized region and including a sensor element body on which the membrane rests. The sensor element body has at least one electrically conductive first conductor and an electrically conductive second conductor electrically insulated from the first conductor. The first conductor is electrically and/or electrolytically conductively connected to the first functionalized region of the membrane, and the second conductor is electrically and/or electrolytically conductively connected to the second functionalized region of the membrane. In another aspect of the present disclosure, a method for fabricating such a sensor element is disclosed.

Abstract: The present disclosure relates to a computer-implemented method for determining at least one measurement uncertainty for at least one measured value of a field device, in which a set of calculation parameters is created that contains at least all standard parameters of a set of standard parameters in the form of a respectively corresponding calculation parameter, and the at least one measurement uncertainty and/or a measurement uncertainty budget is calculated and/or specified based upon at least one calculation parameter value of at least one calculation parameter. Each standard parameter of the set of standard parameters comprising at least one standard parameter represents an independent variable causing the measurement uncertainty. To each calculation parameter is assigned at least one calculation parameter value in the form of at least one standard parameter value, one device parameter value, and/or one application parameter value.

Abstract: The present disclosure relates to a device in particular, a sensor for determining a measurand correlated with a concentration of an analyte in a measuring medium, including a housing that has a region provided for contacting the measuring medium, a fluid line arranged in the housing, an interface that is arranged within the region provided for contacting the measuring medium and has a first side which is in contact with the fluid line and a second side which is in contact with an environment of the housing in particular, with the measuring medium in contact with the housing, a first reservoir that is arranged in the housing and fluidically connected to the fluid line and which contains a reagent intended for contacting and/or interacting with the analyte, and a transport mechanism that is designed to transport reagent from the first reservoir into the fluid line.

Abstract: An installation for producing bags from two-layer plastic film includes a film gripper for drawing the plastic film into a tool at a first station, and a rotary conveyor belt for conveying the film through a plurality of stations. The film gripper is designed to guide the plastic film through the first station to a second station.

Abstract: A reference half-cell for application in an electrochemical sensor, comprising a housing, in which a chamber containing a reference electrolyte is formed, wherein the reference electrolyte is in contact with a medium surrounding the housing via a liquid junction arranged in a wall of the housing, wherein the liquid junction comprises a porous diaphragm, and wherein the diaphragm has, at least partially, a coating, which comprises at least one metal.

Abstract: A reference half-cell for application in an electrochemical sensor, comprising a housing, in which a chamber containing a reference electrolyte is formed, wherein the reference electrolyte (5, 105) is in contact with a medium surrounding the housing via a liquid junction arranged in a wall of the housing, wherein the liquid junction comprises a porous diaphragm, especially a porous ceramic diaphragm, and wherein the diaphragm has, at least partially, a coating, which comprises at least one metal.

Abstract: The present invention relates to a method for the automated production of a workpiece having at least one diaphragm, including a workpiece for an electrochemical sensor, including providing a workpiece that has a wall with at least one continuous opening through the wall, wherein a diaphragm body is affixed in the at least one opening, such that the diaphragm body completely fills a cross-section of the opening, and processing the diaphragm body by means of a laser.

Abstract: Gear mechanism, in particular coaxial gear mechanism or linear gear mechanism, having a toothing system, a tooth carrier with radially oriented guides, teeth which are received in the guides for engagement with the toothing system, the teeth being mounted in the guides such that they can be displaced radially relative to the tooth carrier in the direction of their longitudinal axis, a cam disk for radially driving the teeth, the tooth carrier comprising a first tooth carrier part and a second tooth carrier part.

Abstract: A measuring arrangement for registering an analyte concentration in a measured medium includes a three electrode arrangement having a working electrode, a reference electrode and a counter electrode. The working electrode includes an analyte-insensitive, redox mediator, and the reference electrode a pH-sensitive electrode. The counter electrode can be formed of an inert, electrically conductive material. The measuring arrangement can be embodied to provide a desired voltage between the working electrode and the reference electrode and to register the electrical current flowing, in such case, through the measured medium, between the counter electrode and the working electrode.

Abstract: A potentiometric probe, comprising: a housing, which has a first chamber, in which a reference half-cell is formed, which is in communication with a medium surrounding the housing via an electrolytic contact location arranged in a wall of the housing. The housing has a second chamber, in which a measuring half cell is formed, wherein the second chamber is closed on one end by a measuring membrane, such that a surface area of the measuring membrane facing away from the second chamber is in contact with the medium surrounding the housing, and wherein the measuring half cell has a lengthwise extension between the measuring membrane and a closure element bounding the measuring half cell on an end lying opposite the measuring membrane. A quotient of a separation of the measuring membrane from the closure element and an outer diameter of the housing amounts to less than 5, especially less than 2.

Abstract: The invention relates to an electrochemical half cell comprising: a housing, a potential sensing element, which is at least partially arranged within the housing and is electrically conductively connected to an electrical terminal pad arranged outside the housing; and an electrolyte that is solidified and arranged within the housing, wherein a plurality of gas bubbles which are in particular uniformly distributed within the volume occupied by the electrolyte, are trapped in the electrolyte.