Abstract: This invention relates generally to isolated monoclonal antibodies that binds to an epitope of the 10 kDa culture filtrate protein (CFP-10) or a peptide fragment thereof, and methods for using the same to detect Mycobacterium tuberculosis.

Abstract: A light irradiation device for irradiating polarized light having a light source, a device-side polarizer for polarizing light of the light source and a measuring device that measures a polarization axis of the light polarized by the device-side polarizer is provided, an extinction ratio of the device-side polarizer being set to 100:1 or more.

Abstract: Manufacturing a surface enhanced Raman spectroscopy (SERS) active structure includes exposing a substrate to produce an exposure pattern then etching the substrate based on the exposure pattern to produce a plurality of nanostructure cores having a plurality of sides extending from the substrate. Adjacent nanostructure cores are separated by core gaps. SERS active material is deposited onto the plurality of nanostructure cores producing a structure having gaps suitable for use in a SERS process.

Abstract: A plasmonic device has a plurality of nanostructures extending from a substrate. Each of the plurality of nanostructures preferably includes a core, a coating of intermediate material covering at least a portion of the core, and a coating of a plasmonic material. Devices are preferably manufactured using lithography to create the cores, and Plasma Enhanced Chemical Vapor Deposition (PECVD) to deposit the intermediate and/or plasmonic materials. Cores can be arranged in any suitable pattern, including one-dimensional or two-dimensional patterns. Devices can be used in airborne analyte detectors, in handheld roadside controlled substance detectors, in genome sequencing device, and in refraction detectors.

Abstract: Manufacturing a surface enhanced Raman spectroscopy (SERS) active structure includes exposing a substrate to produce an exposure pattern then etching the substrate based on the exposure pattern to produce a plurality of nanostructure cores having a plurality of sides extending from the substrate. Adjacent nanostructure cores are separated by core gaps. SERS active material is deposited onto the plurality of nanostructure cores producing a structure having gaps suitable for use in a SERS process.