Patents by Inventor Thomas Young Chang

Thomas Young Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10889857
    Abstract: Apparatus and methods relating to DNA sequencing are provided. In one embodiment, a DNA sequencing device includes a nanochannel having a width that is approximately 0.3 nm to approximately 20 nm. A pair of electrodes having portions exposed to the nanochannel may form a tunneling current electrode (TCE) with an electrode gap of approximately 0.1 nm to approximately 2 nm, and more particularly about 0.3 nm to about 1 nm. In one embodiment, at least one of the pair of electrodes is formed as a suspended electrode. An actuator may be associated with the suspended electrode to displace it relative to the other electrode. In various embodiments, the nanochannel and/or the electrodes may be formed using thermal reflow processes to reduce the size of such features.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: January 12, 2021
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Xiaomin Yang, ShuaiGang Xiao, David S. Kuo, Koichi Wago, Thomas Young Chang
  • Patent number: 10884601
    Abstract: In general, the subject matter described in this disclosure can be embodied in methods, systems, and computer-readable devices. A computing device presents a user interface that includes first and second images. The computing device receives first user input that moves the user interface in a first direction. The computing device moves the user interface in the first direction by moving the first and second images in the first direction, and modifying a presentation of the second image at the same time that the second image is moved in the first direction, to indicate that the second image is an image that is pannable. The computing device receives second user input that interacts with the second image to pan the second image. The computing device pans the second image by replacing a first portion of the second image with a second portion of the second image.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: January 5, 2021
    Assignee: Google LLC
    Inventors: William Young Chang, Dana A. Bright, Thomas Homer Rutledge, Soufi Esmaeilzadeh, Antin Harasymiv, Su Chuin Leong
  • Publication number: 20200385799
    Abstract: Apparatus and methods to identify nucleotides of a DNA strand. The method includes exposing the DNA strand to a first dye or peptide, attaching the first dye or peptide to a first type of nucleotide (A,T,C,G) of the DNA strand, the first dye or peptide changing a conductance of the first type of nucleotide to which the first dye or peptide is attached, and measuring a tunneling current signal for all nucleotides of the DNA strand, the changed conductance of the first type of nucleotide providing amplified tunneling current discrimination of the nucleotides of the DNA strand.
    Type: Application
    Filed: August 24, 2020
    Publication date: December 10, 2020
    Inventors: Thomas Young CHANG, Philip L. STEINER, Kim Yang LEE, David S. KUO
  • Publication number: 20200377939
    Abstract: A DNA sequencing device and related methods, wherein the device includes a substrate, a nanochannel formed in the substrate, a first electrode positioned on a first side of the nanochannel, and a second electrode. The second electrode is positioned on a second side of the nanochannel opposite the first electrode and is spaced apart from the first electrode to form an electrode gap that is exposed in the nanochannel. At least a portion of first electrode is movable relative to the second electrode to decrease a size of the electrode gap.
    Type: Application
    Filed: June 23, 2020
    Publication date: December 3, 2020
    Inventors: Kim Yang Lee, Thomas Young Chang, David S. Kuo, ShuaiGang Xiao, Xiaomin Yang, Koichi Wago
  • Publication number: 20200371064
    Abstract: A DNA sequencing device, and related method, which include an electrode and a plurality of spaced apart alignment structures. The electrode defines an electrode gap, the electrode being operable to detect a change in tunneling current as a DNA strand passes through the electrode gap. The plurality of spaced apart alignment structures are arranged to position nucleotides of the DNA strand in a predetermined orientation as the DNA strand passes through the electrode gap.
    Type: Application
    Filed: July 28, 2020
    Publication date: November 26, 2020
    Inventors: Thomas Young CHANG, David S. KUO, Kim Yang LEE, Koichi WAGO
  • Patent number: 10844431
    Abstract: Apparatus and methods to a DNA sequencing device and related methods that includes a substrate, a nanochannel formed in the substrate, a first electrode, a second electrode arranged opposite the first electrode, a distance between the first and second electrodes defining an electrode gap that is exposed within the nanochannel, and at least one actuator operable to move at least one of the first and second electrodes to adjust a size of the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: November 24, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, Kim Yang Lee, David S. Kuo, Erik J. Hutchinson
  • Patent number: 10761058
    Abstract: A DNA sequencing device, and related method, which include an electrode and a plurality of spaced apart alignment structures. The electrode defines an electrode gap, the electrode being operable to detect a change in tunneling current as a DNA strand passes through the electrode gap. The plurality of spaced apart alignment structures are arranged to position nucleotides of the DNA strand in a predetermined orientation as the DNA strand passes through the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: September 1, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, David S. Kuo, Kim Yang Lee, Koichi Wago
  • Patent number: 10752947
    Abstract: Apparatus and methods to identify nucleotides of a DNA strand. The method includes exposing the DNA strand to a first dye or peptide, attaching the first dye or peptide to a first type of nucleotide (A,T,C,G) of the DNA strand, the first dye or peptide changing a conductance of the first type of nucleotide to which the first dye or peptide is attached, and measuring a tunneling current signal for all nucleotides of the DNA strand, the changed conductance of the first type of nucleotide providing amplified tunneling current discrimination of the nucleotides of the DNA strand.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: August 25, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, Philip L. Steiner, Kim Yang Lee, David S. Kuo
  • Publication number: 20200255895
    Abstract: A DNA sequencing device, and related methods, include a nanochannel sized to receive a DNA strand, a first electrode member exposed within the nanochannel, and a second electrode member exposed within the nanochannel and spaced apart from the first electrode to form an electrode gap. The second electrode member has a wedge shaped profile, and the first and second electrode members are operable to detect a change in electronic signal as the DNA strand passes through the electrode gap.
    Type: Application
    Filed: April 29, 2020
    Publication date: August 13, 2020
    Inventors: Kim Yang LEE, David S. KUO, Thomas Young CHANG, Xiaomin YANG, ShuaiGang XIAO, Koichi WAGO
  • Publication number: 20200249195
    Abstract: A DNA sequencing device, and related methods, include a nanopore or nanochannel structure, and a nanoelectrode. The nanoelectrode includes electrode members having free ends exposed within the nanopore or nanochannel structure, an electrode gap defined between of the free ends, and plated portions formed on the free ends to provide a reduced sized for the electrode gap.
    Type: Application
    Filed: April 21, 2020
    Publication date: August 6, 2020
    Inventors: David S. KUO, Xiaomin YANG, ShuaiGang XIAO, Kim Yang LEE, Koichi R. WAGO, Thomas Young CHANG
  • Patent number: 10731210
    Abstract: A DNA sequencing device and related methods, wherein the device includes a substrate, a nanochannel formed in the substrate, a first electrode positioned on a first side of the nanochannel, and a second electrode. The second electrode is positioned on a second side of the nanochannel opposite the first electrode, and is spaced apart from the first electrode to form an electrode gap that is exposed in the nanochannel. At least a portion of first electrode is movable relative to the second electrode to decrease a size of the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: August 4, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Kim Yang Lee, Thomas Young Chang, David S. Kuo, ShuaiGang Xiao, Xiaomin Yang, Koichi Wago
  • Patent number: 10655164
    Abstract: Apparatus and methods to sequence DNA. A DNA sequencing device includes a passage, a first electrode, and a second electrode. The passage has a width and a length. The first and second electrodes are exposed within the passage and spaced apart from each other to form an electrode gap. The electrode gap is no greater than about 2 nm. The DNA sequencing device is operable to measure with the first and second electrodes a change in electronic signal in response to nucleotides of a DNA strand passing through the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 19, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Koichi Wago, ShuaiGang Xiao, Xiaomin Yang, Kim Yang Lee, David S. Kuo, Thomas Young Chang
  • Patent number: 10641726
    Abstract: A DNA sequencing device, and related methods, include a nanopore or nanochannel structure, and a nanoelectrode. The nanoelectrode includes electrode members having free ends exposed within the nanopore or nanochannel structure, an electrode gap defined between of the free ends, and plated portions formed on the free ends to provide a reduced sized for the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 5, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: David S. Kuo, Xiaomin Yang, ShuaiGang Xiao, Kim Yang Lee, Koichi Wago, Thomas Young Chang
  • Patent number: 10640827
    Abstract: A DNA sequencing device, and related methods, include a nanochannel sized to receive a DNA strand, a first electrode member exposed within the nanochannel, and a second electrode member exposed within the nanochannel and spaced apart from the first electrode to form an electrode gap. The second electrode member has a wedge shaped profile, and the first and second electrode members are operable to detect a change in electronic signal as the DNA strand passes through the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 5, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Kim Yang Lee, David S. Kuo, Thomas Young Chang, Xiaomin Yang, ShuaiGang Xiao, Koichi Wago
  • Patent number: 10636444
    Abstract: An apparatus includes a first magnetic layer. A second magnetic layer overlies the first magnetic layer and is magnetically softer than the first magnetic layer. An exchange control layer is between the first magnetic layer and the second magnetic layer. The includes a higher Ms (saturation magnetization) than the first magnetic layer at room temperature.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: April 28, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, Thomas P. Nolan
  • Patent number: 10564119
    Abstract: A DNA sequencing device includes a first layer having a nanochannel formed therein, and a pair of electrodes arranged vertically relative to each other and spaced apart to define an electrode gap. The electrode gap is exposed in the nanochannel, and the electrode gap is in the range of about 0.3 nm to about 2 nm.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: February 18, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: David S. Kuo, ShuaiGang Xiao, Kim Yang Lee, Xiaomin Yang, Koichi Wago, Thomas Young Chang
  • Publication number: 20190265856
    Abstract: In general, the subject matter described in this disclosure can be embodied in methods, systems, and computer-readable devices. A computing device presents a user interface that includes first and second images. The computing device receives first user input that moves the user interface in a first direction. The computing device moves the user interface in the first direction by moving the first and second images in the first direction, and modifying a presentation of the second image at the same time that the second image is moved in the first direction, to indicate that the second image is an image that is pannable. The computing device receives second user input that interacts with the second image to pan the second image. The computing device pans the second image by replacing a first portion of the second image with a second portion of the second image.
    Type: Application
    Filed: May 13, 2019
    Publication date: August 29, 2019
    Inventors: William Young Chang, Dana A. Bright, Thomas Homer Rutledge, Soufi Esmaeilzadeh, Antin Harasymiv, Su Chuin Leong
  • Publication number: 20190180780
    Abstract: An apparatus includes a first magnetic layer. A second magnetic layer overlies the first magnetic layer and is magnetically softer than the first magnetic layer. An exchange control layer is between the first magnetic layer and the second magnetic layer. The includes a higher Ms (saturation magnetization) than the first magnetic layer at room temperature.
    Type: Application
    Filed: February 20, 2019
    Publication date: June 13, 2019
    Inventors: Thomas Young CHANG, Thomas P. NOLAN
  • Patent number: 10289297
    Abstract: In general, the subject matter described in this disclosure can be embodied in methods, systems, and computer-readable devices. A computing device presents a user interface that includes first and second images. The computing device receives first user input that moves the user interface in a first direction. The computing device moves the user interface in the first direction by moving the first and second images in the first direction, and modifying a presentation of the second image at the same time that the second image is moved in the first direction, to indicate that the second image is an image that is pannable. The computing device receives second user input that interacts with the second image to pan the second image. The computing device pans the second image by replacing a first portion of the second image with a second portion of the second image.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: May 14, 2019
    Assignee: Google LLC
    Inventors: William Young Chang, Dana A. Bright, Thomas Homer Rutledge, Soufi Esmaeilzadeh, Antin Harasymiv, Su Chuin Leong
  • Publication number: 20190122695
    Abstract: An apparatus includes a first magnetic layer. A second magnetic layer overlies the first magnetic layer and is magnetically softer than the first magnetic layer. An exchange control layer is between the first magnetic layer and the second magnetic layer. The exchange control layer is magnetic and increases vertical coupling between the first magnetic layer and the second magnetic layer.
    Type: Application
    Filed: October 25, 2017
    Publication date: April 25, 2019
    Inventors: Thomas Young CHANG, Thomas Patrick NOLAN