Patents by Inventor Tianmei Ouyang

Tianmei Ouyang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANALYTE SENSORS AND METHODS OF USING SAME
    Publication number: 20180252660
    Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.
    Type: Application
    Filed: April 27, 2018
    Publication date: September 6, 2018
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
  • Analyte sensors having temperature independent membranes
    Patent number: 10022076
    Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane structure with an analyte permeability that is substantially temperature independent. The devices also include a sensing layer disposed on a working electrode of in vivo analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: July 17, 2018
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Udo Hoss, Benjamin J. Feldman, Tianmei Ouyang
  • Self-powered analyte sensor
    Patent number: 10004441
    Abstract: Generally, embodiments of the invention relate to self-powered analyte determining devices (e.g., electrochemical analyte monitoring systems) that include a working electrode, a counter electrode, and an optional resistance value, where the working electrode includes analyte sensing components and the self-powered analyte determining device spontaneously passes a current directly proportional to analyte concentration in the absence of an external power source. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: June 26, 2018
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang
  • Stabilized Lactate Responsive Enzymes, Electrodes and Sensors, and Methods for Making and Using the Same
    Publication number: 20180148758
    Abstract: Enzyme compositions including lactate responsive enzyme and stabilizing agent, including electrodes, sensors, and systems having the same. The stabilizing agent stabilizes the lactate responsive enzyme in a manner sufficient to increase sensitivity to lactate, such as for use in in vivo detection of lactate. In some compositions the lactate responsive enzyme is lactate oxidase and the sensor includes a heterocycle-containing polymer and a crosslinker.
    Type: Application
    Filed: January 26, 2018
    Publication date: May 31, 2018
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Tianmei Ouyang, Benjamin J. Feldman, Kuan-chou Chen
  • Analyte sensors and methods of using same
    Patent number: 9983161
    Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: May 29, 2018
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
  • Cationic Polymer Based Wired Enzyme Formulations for Use in Analyte Sensors
    Publication number: 20180094290
    Abstract: Embodiments of the invention include analyte-responsive compositions and electrochemical analyte sensors having a sensing layer that includes an analyte-responsive enzyme and a cationic polymer. Also provided are systems and methods of making the sensors and using the electrochemical analyte sensors in analyte monitoring.
    Type: Application
    Filed: December 6, 2017
    Publication date: April 5, 2018
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Benjamin J. Feldman, Tianmei Ouyang, Zenghe Liu
  • Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
    Patent number: 9914952
    Abstract: Embodiments of the present disclosure relate to stabilized lactate oxidase compositions, and electrodes, sensors and systems that include the same. Also provided are methods for making the compositions and for detecting and/or measuring lactate in vivo with stable lactate enzyme compositions.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: March 13, 2018
    Assignee: Abbott Diabetes Care, Inc.
    Inventors: Tianmei Ouyang, Benjamin J. Feldman, Kuan-chou Chen
  • Cationic polymer based wired enzyme formulations for use in analyte sensors
    Patent number: 9885073
    Abstract: Embodiments of the invention include analyte-responsive compositions and electrochemical analyte sensors having a sensing layer that includes an analyte-responsive enzyme and a cationic polymer. Also provided are systems and methods of making the sensors and using the electrochemical analyte sensors in analyte monitoring.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: February 6, 2018
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Benjamin J. Feldman, Tianmei Ouyang, Zenghe Liu
  • Temperature Insensitive In Vivo Analyte Devices, Methods and Systems
    Publication number: 20180014766
    Abstract: Disclosed herein are membrane structures for use in analyte sensors, where the membrane structures exhibit low temperature sensitivity.
    Type: Application
    Filed: September 28, 2017
    Publication date: January 18, 2018
    Inventors: Tianmei Ouyang, Benjamin J. Feldman, Udo Hoss, Balasubrahmanya S. Bommakanti, Gurinder Sandhu
  • Analyte Sensors Having a Membrane with Low Temperature Sensitivity
    Publication number: 20180014761
    Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane with low temperature sensitivity. The sensing layer is disposed on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Application
    Filed: September 28, 2017
    Publication date: January 18, 2018
    Inventors: Tianmei Ouyang, Zenghe Liu, Yohannes Goti, Benjamin J. Feldman, Udo Hoss
  • Temperature insensitive in vivo analyte devices, methods and systems
    Patent number: 9775549
    Abstract: Disclosed herein are membrane structures for use in analyte sensors, where the membrane structures exhibit low temperature sensitivity.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: October 3, 2017
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Tianmei Ouyang, Benjamin J. Feldman, Udo Hoss, Balasubrahmanya S. Bommakanti, Gurinder Sandhu
  • Heterocyclic nitrogen containing polymer coated analyte monitoring device and methods of use
    Patent number: 9777307
    Abstract: The present invention is directed to membranes composed of heterocyclic nitrogen groups, such as vinylpyridine and to electrochemical sensors equipped with such membranes. The membranes are useful in limiting the diffusion of an analyte to a working electrode in an electrochemical sensor so that the sensor does not saturate and/or remains linearly responsive over a large range of analyte concentrations. Electrochemical sensors equipped with membranes described herein demonstrate considerable sensitivity and stability, and a large signal-to-noise ratio, in a variety of conditions.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: October 3, 2017
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Benjamin J. Feldman, Tianmei Ouyang, Hyun Cho
  • Analyte sensors having a membrane with low temperature sensitivity
    Patent number: 9775544
    Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane with low temperature sensitivity. The sensing layer is disposed on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: October 3, 2017
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Tianmei Ouyang, Zenghe Liu, Yohannes Goti, Benjamin J. Feldman, Udo Hoss
  • In vivo enzyme activity sensors and methods
    Publication number: 20170258378
    Abstract: In vivo monitoring devices and systems for enzymes and/or analytes including devices having a reactant reservoir are provided.
    Type: Application
    Filed: March 13, 2017
    Publication date: September 14, 2017
    Inventors: Mark Eshoo, Benjamin Feldman, Tianmei Ouyang, Lam Tran
  • Analyte Sensors Having Temperature Independent Membranes
    Publication number: 20170258377
    Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane structure with an analyte permeability that is substantially temperature independent. The devices also include a sensing layer disposed on a working electrode of in vivo analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Application
    Filed: May 26, 2017
    Publication date: September 14, 2017
    Inventors: Udo Hoss, Benjamin J. Feldman, Tianmei Ouyang
  • Self-Powered Analyte Sensor
    Publication number: 20170188904
    Abstract: Generally, embodiments of the invention relate to self-powered analyte determining devices (e.g., electrochemical analyte monitoring systems) that include a working electrode, a counter electrode, and an optional resistance value, where the working electrode includes analyte sensing components and the self-powered analyte determining device spontaneously passes a current directly proportional to analyte concentration in the absence of an external power source. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Application
    Filed: November 14, 2016
    Publication date: July 6, 2017
    Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang
  • Self-powered analyte sensor
    Patent number: 9668684
    Abstract: Generally, embodiments of the invention relate to self-powered analyte determining devices (e.g., electrochemical analyte monitoring systems) that include a working electrode, a counter electrode, and an optional resistance value, where the working electrode includes analyte sensing components and the self-powered analyte determining device spontaneously passes a current directly proportional to analyte concentration in the absence of an external power source. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: June 6, 2017
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Benjamin Feldman, Zenghe Liu, Tianmei Ouyang
  • Analyte sensors having temperature independent membranes
    Patent number: 9662055
    Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane structure with an analyte permeability that is substantially temperature independent. The devices also include a sensing layer disposed on a working electrode of in vivo analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: May 30, 2017
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Udo Hoss, Benjamin J. Feldman, Tianmei Ouyang
  • Analyte Sensors and Methods of Using Same
    Publication number: 20170138886
    Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.
    Type: Application
    Filed: November 23, 2016
    Publication date: May 18, 2017
    Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
  • Test Strip, Meter, and Method for Assaying Enzyme Activity
    Publication number: 20170121754
    Abstract: Embodiments of the present disclosure relate to an electrochemical test strip comprising a reagent system for assaying activity of an enzyme that may be present is a sample. The present disclosure also provides a meter with a port for receiving the test strip and electronics for determining activity of the enzyme, if present, in the sample. Method for using the test strip for determining activity of the enzyme is also described.
    Type: Application
    Filed: June 4, 2015
    Publication date: May 4, 2017
    Inventors: Benjamin J. Feldman, Tianmei Ouyang