Patents by Inventor Tibor Szabo

Tibor Szabo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6335469
    Abstract: The invention relates to high purity (1R,2S,4R)-(−)-2-[(2′-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2′-{N,N-dimethylamino}-ethyl)]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: January 1, 2002
    Assignee: Orion Corporation
    Inventors: Gyula Lukács, Gyula Simig, Tibor Mezei, Zoltán Budai, Márta Porcs-Makkay, György Krasznai, Kálmán Nagy, Györgyi Donáth Vereczkey, Tibor Szabó, Norbert Németh, János Szulágyi
  • Patent number: 6242386
    Abstract: A process for preparing (1R,2S,4R)-(−)-2-[(2′-[N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo [2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof with higher yields and higher grades of purity.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: June 5, 2001
    Assignee: Egis Gyógyszergyár Rt.
    Inventors: Gyula Lukács, Gyula Simig, Tibor Mezei, Zoltán Budai, Márta Porcs-Makkay, György Krasznai, Kálmán Nagy, Györgyi Donáth Vereczkey, Tibor Szabó, Norbert Németh, János Szulágyi
  • Patent number: 6069269
    Abstract: New process for the preparation of prostaglandin E1 of formula (I) starting from the compound of formula (II).
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: May 30, 2000
    Assignee: CHINOIN Gyogyszer es Vegyeszeti
    Inventors: Gyula Dalmadi, Felix Hajdu, Istvan Hermecz, Karoly Mozsolits, Tibor Szabo, Zoltan Szeverenyi, Ervin Vajda
  • Patent number: 5466833
    Abstract: The invention relates to a novel process for the preparation of 13,14-dihydro-15 (R)-17-phenyl-18,19,20-trinor-PGF.sub.2.alpha. isopropyl ester of the formula (I)--wherein R stands for saturated or unsaturated straight, branched or cyclic C.sub.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: November 14, 1995
    Assignees: Kabi Pharmacia AB, Chinoin Ltd.
    Inventors: Jozsef Ivanics, Tibor Szabo, Istvan Hermecz, Gyula Dalmadi, Jozsefne Ivanics, Gaborne Kovacs, Resul Bahram
  • Patent number: 5370170
    Abstract: A method for producing a cast-iron cylinder liner for piston engines in which a metal chill mold (1) is used which has a tubular mold cavity (2) lined with a layer of a hardening molding material or green sand (3). The melt (7) is introduced into the mold cavity from above in such a manner that the cooling effect from the chill mold and the lining provides a frontage of solidification directed upwardly from the bottom.
    Type: Grant
    Filed: April 2, 1993
    Date of Patent: December 6, 1994
    Assignee: AB Volvo
    Inventors: Bertil Sander, Sven-Erik Dahlberg, Tibor Szabo, Berndt Gyllensten
  • Patent number: 5008386
    Abstract: The invention relates to novel partially methylated carboxyacyl-cyclodextrins of the general formula (I), ##STR1## wherein A means the cyclodextrin skeleton of the general formula (II) ##STR2## containing the substituents in the position labelled by the wavy line; W stands for an alkylene, alkenylene or arylene group or the substituted derivatives thereof;R means hydrogen, an alkyl, aryl or aralkyl group;m is 6, 7 or 8;n is an integer from 1 to 2m; andp is 2m-n+z, wherein the value of z is from 0 to 3as well as their salts.The novel derivatives induce less haemolytic effect than the cyclodextrin compounds used as starting materials.
    Type: Grant
    Filed: October 12, 1988
    Date of Patent: April 16, 1991
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Tibor Szabo, Laszlo Institoris, Jozsef Szejtli, Lajos Szente, Ildiko Jodal
  • Patent number: 4820852
    Abstract: The subject of the invention is an improved process for the industrial scale preparation of the compounds of the formula ##STR1## and salts thereof by acylating the hexitols of the formula (II) with an anhydride of the formula (II) at a temperature of 0.degree.-30.degree. C. in the presence of an organic base and a catalyst of the formula (IV) in a dipolar-aprotic or aprotic solvent.
    Type: Grant
    Filed: March 31, 1988
    Date of Patent: April 11, 1989
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara
    Inventors: Tibor Szabo, Ildiko Vidra nee Sandor, Gyula Dalmadi, Judit Kaczmarek nee Sebestyen, Janos ri
  • Patent number: 4559001
    Abstract: A glass panel whose edges are to be sealed is displaced in an upright condition standing on one edge into a sealing station where the conveyor supporting it raises somewhat whereupon suction grippers carried on a stationary frame engage within the edges of the workpiece. Then the conveyor lowers away from the workpiece, which is still upright, so that all of its edges are unobstructed. An extruder then moves vertically and horizontally around the workpiece to seal its edges. An unloading conveyor presses its own set of suction grippers against a face of the workpiece within its edges so they stick to the sealed workpiece. The suction grippers of the stationary frame then release the workpiece to those of the unloading conveyor which subsequently displaces it while it is still upright into a takeoff station.
    Type: Grant
    Filed: March 21, 1984
    Date of Patent: December 17, 1985
    Assignee: Flachglas Aktiengesellschaft
    Inventors: Heinrich Wiedenhofer, Tibor Szabo
  • Patent number: 4321845
    Abstract: An automatic bar puller for a numerically controlled turret lathe, the puller being mounted on one station of the turret and have a detent actuated jaw that grips the end of a chuck mounted workpiece on triggering of a contact stop on the puller by the workpiece, and, the lathe controlling displacement of the workpiece and release of the jaw.
    Type: Grant
    Filed: June 16, 1980
    Date of Patent: March 30, 1982
    Inventors: Tibor Szabo, Robert L. Karr
  • Patent number: 4292699
    Abstract: A grinding machine, particularly designed for machining a chipbreaker groove into the cutting edge of a cutting tool, the grinding machine has a support base and an abrasion wheel mounted to the support base, a workpiece table with anchoring fasteners for securing a workpiece to the table; a pedestal fixed to the support base with a pivot block connected to the pedestal by a vertical adjustment mechanism, the pivot block having a cooperating slide and pivot mechanism connecting the pivot block to the work-piece table for pivoting the table about a horizontal axis and sliding the table along the same horizontal axis; stop devices for delimiting the degree of pivot and length of slide of the work-piece table; and, guage indicators for defining the degree of pivot height and slide length of the work table.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: October 6, 1981
    Inventor: Tibor Szabo
  • Patent number: 4283413
    Abstract: New compounds and a process for making the same, for use in inhibiting aggregation in human blood and inhibiting the growth of tumors, said compounds being of the general formula: ##STR1## wherein R is hydrogen, alkanoyl, substituted alkanoyl, aralkanoyl or aroyl and represents .alpha. or .beta. steric position or .alpha. and .beta. position, with the provision that if R stands for p-phenyl-benzoyl then methoxy in the position 2 may stand only in .alpha. or only in .beta. steric position.
    Type: Grant
    Filed: December 12, 1979
    Date of Patent: August 11, 1981
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara RT.
    Inventors: Tibor Szabo, Laszlo Institoris, Gabor Kovacs, Istvan Stadler, Bela Koszegi
  • Patent number: 4257962
    Abstract: Racemic or optically active compounds with antitumor activity of the formula: ##STR1## wherein X is oxygen or sulfur;R.sup.1 is hydrogen, C.sub.1 to C.sub.4 alkanoyl, benzoyl or phenyl-substituted benzoyl;R.sup.2 is hydrogen or C.sub.1 to C.sub.4 alkanoyl;R.sup.3 is C.sub.2 to C.sub.40 straight or branched chain alkyl substituted by hydroxy, epoxy, amino, C.sub.1 to C.sub.6 alkylamino, C.sub.1 to C.sub.6 dialkylamino, C.sub.1 to C.sub.6 alkanoyloxy or, C.sub.1 to C.sub.4 alkoxycarbonyl; cyclohexyl, phenyl unsubstituted or substituted by halogen, amino, C.sub.1 to C.sub.4 alkyl-substituted amino, C.sub.1 to C.sub.4 alkoxy, nitro, or hydroxy; C.sub.1 to C.sub.6 alkanoyl; allyl or phenyl-C.sub.1 to C.sub.4 alkyl unsubstituted or substituted by a C.sub.2 to C.sub.6 alkene group; or where X is sulfur R.sup.3 is as defined above or is C.sub.1 to C.sub.40 straight or branched chain alkyl; and.about. represents the exo- or endo-steric position in the ring and indicates an .alpha.- or .beta.
    Type: Grant
    Filed: September 15, 1978
    Date of Patent: March 24, 1981
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Tibor Szabo, Laszlo Institoris, Gabor Kovacs, Gyula Dalmadi, Bela Koszegi, Istvan Stadler
  • Patent number: 4005974
    Abstract: A mold closing unit for an injection molding machine having a double acting mold closing piston, a closable valve interconnecting both sides of the piston, an auxiliary piston, and a piston rod for each piston, each connecting one side of the pistons to the movable mold part wherein the cylinder spaces on mold closing side of the two pistons are permanently communicated whereby the change in volume of the combined working space is proportional to the areas of the piston rods. The cylinder for the auxiliary piston is placed laterally of the main cylinder so that the overall length of the machine is held to a minimum. An additional return piston is also provided.
    Type: Grant
    Filed: January 24, 1975
    Date of Patent: February 1, 1977
    Assignee: Tibor Szabo
    Inventor: Tibor Szabo