Patents by Inventor Timothy Francis Gallagher

Timothy Francis Gallagher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anthranilamide inhibitors of aurora kinase
    Patent number: 7884098
    Abstract: The present invention relates to a compound represented by the following formula: or a pharmaceutically acceptable salt thereof; wherein R1, R1? R2, R3, R4, R5, r and s are as defined herein. Compounds of the present invention are useful in the treatment of diseases associated with Aurora kinase activity such as cancer.
    Type: Grant
    Filed: January 25, 2008
    Date of Patent: February 8, 2011
    Assignee: GlaxoSmithKline LLC
    Inventors: Jeffrey Michael Axten, Deborah L. Bryan, David Harold Drewry, Thomas H Faitg, Timothy Francis Gallagher, Neil W Johnson, Jiri Kasparec, Jeffrey M Ralph, Domingos J. Silva
  • Antimicrobial Compounds
    Publication number: 20100081650
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: November 17, 2009
    Publication date: April 1, 2010
    Inventors: Jeffrey Michael Axten, Robert A. Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • ANTHRANILAMIDE INHIBITORS OF AURORA KINASE
    Publication number: 20100016318
    Abstract: The present invention relates to a compound represented by the following formula: or a pharmaceutically acceptable salt thereof; wherein R1, R1? R2, R3, R4, R5, r and s are as defined herein. Compounds of the present invention are useful in the treatment of diseases associated with Aurora kinase activity such as cancer.
    Type: Application
    Filed: January 25, 2008
    Publication date: January 21, 2010
    Applicant: SMITHKLINE BEECHAM CORPORATION
    Inventors: Jeffrey Michael Axten, Deborah L. Bryan, David Harold Drewry, Thomas H. Faitg, Timothy Francis Gallagher, Neil W. Johnson, Jiri Kasparec, Jeffrey M. Ralph, Domingos J. Silva
  • Antibacterial compounds
    Patent number: 7622481
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: November 24, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey Michael Axten, Robert A Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • Antibacterial agents
    Patent number: 7618959
    Abstract: Quinoline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: November 17, 2009
    Assignee: SmithKlineBeecham Corp
    Inventors: Jeffrey Michael Axten, Timothy Francis Gallagher, William Henry Miller, Mark Andrew Seefeld
  • Compounds
    Patent number: 7498326
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man. The piperidine derivatives include compounds of formula (I): wherein RA, AB, n, R3, R2 and R4 are defined herein. For example, RA is an optionally substituted bicyclic carbocyclic or heterocyclic ring system, and R4 is a group U-R5 in which R5 is an optionally substituted bicyclic heterocyclic ring system as defined herein (e.g. optionally substituted pyrido [3,2, -b][1,4] thiazin-yl).
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: March 3, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey Michael Axten, Robert A Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • Oxazoles for treating cytokine mediated diseases
    Publication number: 20040106793
    Abstract: This invention relates to the novel oxazole compounds of Formula (I) and novel pharmaceutical compositions comprising a compound of Formula (I) and a pharmaceutically acceptable diluent or carrier.
    Type: Application
    Filed: July 9, 2003
    Publication date: June 3, 2004
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Jeffrey Charles Boehm, Susan Mary Thompson
  • Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses
    Patent number: 6730683
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: May 4, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Timothy Francis Gallagher, Jeffrey Charles Boehm, Jerry Leroy Adams
  • Compounds
    Patent number: 6645989
    Abstract: Novel 2,4,5-triaryl imidazole compounds and compositions for use in therapy.
    Type: Grant
    Filed: March 27, 2001
    Date of Patent: November 11, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, John C. Lee, John Richard White
  • Substituted imidazole compounds
    Patent number: 6562832
    Abstract: Novel 1,4,5-subsituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: December 15, 1999
    Date of Patent: May 13, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, Timothy Francis Gallagher
  • Novel compounds
    Publication number: 20030064997
    Abstract: Novel 2,4,5-triaryl imidazole compounds and compositions for use in therapy.
    Type: Application
    Filed: March 27, 2001
    Publication date: April 3, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, John C. Lee, John Richard White
  • Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses
    Publication number: 20020198206
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Application
    Filed: June 10, 2002
    Publication date: December 26, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Timothy Francis Gallagher, Jeffrey Charles Boehm, Jerry Leroy Adams
  • Novel compounds
    Publication number: 20020188122
    Abstract: Novel 1, 4, 5- substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Application
    Filed: February 27, 2001
    Publication date: December 12, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Peter William Sheldrake, Timothy Francis Gallagher, Ravi Shanker Garigipati, Paul Elliot Bender, Jeffrey Charles Boehm, Joseph Sisko, Zhi-Qiang Peng, John C. Lee
  • Oxazoles for treating cytokine mediated diseases
    Publication number: 20020169173
    Abstract: This invention relates to the novel oxazole compounds of Formula (I) and novel pharmaceutical compositions comprising a compound of Formula (I) and a pharmaceutically acceptable diluent or carrier.
    Type: Application
    Filed: January 25, 2001
    Publication date: November 14, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Jeffrey Charles Boehm, Susan Mary Thompson
  • Amino substituted pyrimidine containing compounds
    Patent number: 6369068
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: April 9, 2002
    Assignee: Smithkline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Irennegbe Kelly Osifo, Jeffrey Charles Boehm
  • compounds of heteroaryl substituted imidazole, their pharmaceutical compositons and uses
    Patent number: 6335340
    Abstract: Compounds of 1,4,5-substituted imidazole wherein one of the substituents can be a substituted pyrimidine, pyridazine or 1,2,4-triazine. These compounds and their pharmaceutical compositions are used in treating cytokine mediated diseases by inhibiting the production of IL-1 (interleukin-1), IL-8 (interleukin-8), and TNF (tumor necrosis factor).
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: January 1, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Timothy Francis Gallagher, Jeffrey Charles Boehm, Jerry Leroy Adams
  • Protease inhibitors
    Patent number: 6331542
    Abstract: The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease, comprising inhibiting said bone loss or excessive cartilage or matrix degradation by administering to a patient in need thereof a compound of the present invention.
    Type: Grant
    Filed: April 19, 2000
    Date of Patent: December 18, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Thomas Joseph Carr, Renee Louise Desjarlais, Timothy Francis Gallagher, Stacie Marie Halbert, Hye-Ja Oh, Scott Kevin Thompson, Daniel Frank Veber, Dennis Shinji Yamashita, Jack Hwekwo Yen
  • Compounds
    Patent number: 6306883
    Abstract: This invention relates to the novel pyrazole compounds of Formula (I), and pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable diluent or carrier. This invention also relates to a method of inhibiting cytokines by a compound of formula (I) and the treatment of cytokines mediated diseases, in mammals, by administration of said compound.
    Type: Grant
    Filed: December 3, 1999
    Date of Patent: October 23, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Ravi Shanker Garigipati, Susan Mary Thompson
  • Oxazoles for treating cytokine mediated diseases
    Patent number: 6288062
    Abstract: This invention relates to the novel oxazole compounds of Formula (I) and novel pharmaceutical compositions comprising a compound of Formula (I) and a pharmaceutically acceptable diluent or carrier. This invention also relates to a method of inhibiting cytokines and the treatment of cytokine mediated diseases, in mammals, thereby by administration of an effective amount of a compound according to Formula (I).
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: September 11, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Jeffrey Charles Boehm, Susan Mary Thompson
  • Compounds
    Patent number: 6268370
    Abstract: Novel 2,4,5-triaryl imidazole compounds and compositions for use in therapy.
    Type: Grant
    Filed: March 16, 1999
    Date of Patent: July 31, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, John C. Lee, John Richard White