Patents by Inventor Tobias Holenstein

Tobias Holenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9381519
    Abstract: An apparatus for separating magnetic particles from a liquid which contains said particles, said liquid being contained in an elongated vessel (11) having a length axis (12), said vessel being arranged in a vessel holder (13) with its length axis (12) in a substantially vertical position, said vessel (11) having a bottom and a tapered cross-section that diminishes towards the bottom of the vessel and a side wall (14) which has an outer surface which forms an angle with the length axis (12) of said vessel (11).
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: July 5, 2016
    Assignee: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Tobias Holenstein, Rolf Schneebeli, Renato Belz
  • Patent number: 9278349
    Abstract: A pipetting device having a modular pipetting unit including a pipetting tip for pipetting of fluid samples and a pump conduit for transferring a negative or positive pressure to the pipetting tip is disclosed. The pipetting tip and a portion of the pump conduit adjoining the pipetting tip mutually define a fluid sample conduit for receiving the fluid samples. The modular pipetting unit is detachably attached to an automated positioning device for positioning the modular pipetting unit. A system and method for pipetting of fluid samples using such a pipetting device are also disclosed wherein pipetting of the fluid samples is performed in such a manner that each pipetted fluid sample volume is smaller than a volume of the fluid sample conduit.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: March 8, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Carsten Haack, Thomas Engel, Tobias Holenstein
  • Publication number: 20150056111
    Abstract: A pipetting device having a modular pipetting unit including a pipetting tip for pipetting of fluid samples and a pump conduit for transferring a negative or positive pressure to the pipetting tip is disclosed. The pipetting tip and a portion of the pump conduit adjoining the pipetting tip mutually define a fluid sample conduit for receiving the fluid samples. The modular pipetting unit is detachably attached to an automated positioning device for positioning the modular pipetting unit. A system and method for pipetting of fluid samples using such a pipetting device are also disclosed wherein pipetting of the fluid samples is performed in such a manner that each pipetted fluid sample volume is smaller than a volume of the fluid sample conduit.
    Type: Application
    Filed: October 30, 2014
    Publication date: February 26, 2015
    Inventors: Carsten Haack, Thomas Engel, Tobias Holenstein
  • Patent number: 8900878
    Abstract: A pipetting device having a modular pipetting unit including a pipetting tip for pipetting of fluid samples and a pump conduit for transferring a negative or positive pressure to the pipetting tip is disclosed. The pipetting tip and a portion of the pump conduit adjoining the pipetting tip mutually define a fluid sample conduit for receiving the fluid samples. The modular pipetting unit is detachably attached to an automated positioning device for positioning the modular pipetting unit. A system and method for pipetting of fluid samples using such a pipetting device are also disclosed wherein pipetting of the fluid samples is performed in such a manner that each pipetted fluid sample volume is smaller than a volume of the fluid sample conduit.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: December 2, 2014
    Assignee: Roche Molecular Systems Inc.
    Inventors: Carsten Haack, Thomas Engel, Tobias Holenstein
  • Patent number: 8778281
    Abstract: A sample preparation dosing unit for liquid dosing is provided comprising an inlet port and an outlet port fluidically coupling the sample preparation dosing unit to a supply and target, respectively; a pump, fluidically arranged between the inlet port and the outlet port; an outlet flow restrictor with an outlet flow resistance, fluidically arranged between a pump outlet and outlet port; and a control arrangement with a branch, a control valve, and a control flow restrictor with a control flow resistance. The branch divides the flow at the pump outlet into an outlet flow through the outlet flow restrictor and into a control flow through the control flow restrictor. The control flow downstream of the control flow restrictor is fed, depending on the state of the control valve, either into the outlet port thereby merging with the outlet flow downstream of the outlet flow restrictor, or into a bypass conduit.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: July 15, 2014
    Assignee: Roche Diagnostics Operations, Inc
    Inventors: Tobias Holenstein, Thomas Engel, Thomas Sidler, Adelrich Zuppiger, Carsten Haack, Alessandro D'Amore, Michael Meyberg, Tobias Greuter, Roland Stoeckli
  • Publication number: 20130256205
    Abstract: An apparatus for separating magnetic particles from a liquid which contains said particles, said liquid being contained in an elongated vessel (11) having a length axis (12), said vessel being arranged in a vessel holder (13) with its length axis (12) in a substantially vertical position, said vessel (11) having a bottom and a tapered cross-section that diminishes towards the bottom of the vessel and a side wall (14) which has an outer surface which forms an angle with the length axis (12) of said vessel (11).
    Type: Application
    Filed: May 22, 2013
    Publication date: October 3, 2013
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Tobias Holenstein, Rolf Schneebeli, Renato Belz
  • Patent number: 8470267
    Abstract: An apparatus for separating magnetic particles from a liquid which contains said particles, said liquid being contained in an elongated vessel (11) having a length axis (12), said vessel being arranged in a vessel holder (13) with its length axis (12) in a substantially vertical position, said vessel (11) having a bottom and a tapered cross-section that diminishes towards the bottom of the vessel and a side wall (14) which has an outer surface which forms an angle with the length axis (12) of said vessel (11).
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: June 25, 2013
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Tobias Holenstein, Rolf Schneebeli, Renato Belz
  • Publication number: 20110030803
    Abstract: A sample preparation dosing unit for liquid dosing is provided comprising an inlet port and an outlet port fluidically coupling the sample preparation dosing unit to a supply and target, respectively; a pump, fluidically arranged between the inlet port and the outlet port; an outlet flow restrictor with an outlet flow resistance, fluidically arranged between a pump outlet and outlet port; and a control arrangement with a branch, a control valve, and a control flow restrictor with a control flow resistance. The branch divides the flow at the pump outlet into an outlet flow through the outlet flow restrictor and into a control flow through the control flow restrictor. The control flow downstream of the control flow restrictor is fed, depending on the state of the control valve, either into the outlet port thereby merging with the outlet flow downstream of the outlet flow restrictor, or into a bypass conduit.
    Type: Application
    Filed: August 4, 2010
    Publication date: February 10, 2011
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Tobias Holenstein, Thomas Engel, Thomas Sidler, Adelrich Zuppiger, Carsten Haack, Alessandro D'Amore, Michael Meyberg, Tobias Greuter, Roland Stoeckli
  • Publication number: 20100284864
    Abstract: An apparatus for separating magnetic particles from a liquid which contains said particles, said liquid being contained in an elongated vessel (11) having a length axis (12), said vessel being arranged in a vessel holder (13) with its length axis (12) in a substantially vertical position, said vessel (11) having a bottom and a tapered cross-section that diminishes towards the bottom of the vessel and a side wall (14) which has an outer surface which forms an angle with the length axis (12) of said vessel (11).
    Type: Application
    Filed: March 21, 2007
    Publication date: November 11, 2010
    Inventors: Tobias Holenstein, Rolf Schneebeli, Renato Belz
  • Publication number: 20100132487
    Abstract: A pipetting device having a modular pipetting unit including a pipetting tip for pipetting of fluid samples and a pump conduit for transferring a negative or positive pressure to the pipetting tip is disclosed. The pipetting tip and a portion of the pump conduit adjoining the pipetting tip mutually define a fluid sample conduit for receiving the fluid samples. The modular pipetting unit is detachably attached to an automated positioning device for positioning the modular pipetting unit. A system and method for pipetting of fluid samples using such a pipetting device are also disclosed wherein pipetting of the fluid samples is performed in such a manner that each pipetted fluid sample volume is smaller than a volume of the fluid sample conduit.
    Type: Application
    Filed: November 23, 2009
    Publication date: June 3, 2010
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Carsten Haack, Thomas Engel, Tobias Holenstein