Patents by Inventor Todd R. Pray

Todd R. Pray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vivo production of cyclic peptides for inhibiting protein-protein interaction
    Patent number: 9040462
    Abstract: The present invention relates to methods and compositions utilizing inteins to generate libraries of cyclic peptides in vivo. The prevent invention also relates to methods for inhibiting protein-protein interaction.
    Type: Grant
    Filed: May 12, 2008
    Date of Patent: May 26, 2015
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: James B. Lorens, Todd R. Pray, Todd M. Kinsella, Mark K. Bennett
  • Ubiquitin ligase assay
    Patent number: 7781182
    Abstract: The invention relates to assays for measuring ubiquitin ligase activity and for identifying modulators of ubiquitin ligase enzymes.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: August 24, 2010
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • UBIQUITIN LIGASE ASSAY
    Publication number: 20090263831
    Abstract: The invention relates to assays for measuring ubiquitin ligase activity and for identifying modulators of ubiquitin ligase enzymes.
    Type: Application
    Filed: October 4, 2006
    Publication date: October 22, 2009
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
    Patent number: 7524642
    Abstract: Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying for agents that modulate the activity of such ubiquitin agents.
    Type: Grant
    Filed: October 2, 2006
    Date of Patent: April 28, 2009
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • IN VIVO PRODUCTION OF CYCLIC PEPTIDES FOR INHIBITING PROTEIN-PROTEIN INTERACTION
    Publication number: 20080261819
    Abstract: The present invention relates to methods and compositions utilizing inteins to generate libraries of cyclic peptides in vivo. The prevent invention also relates to methods for inhibiting protein-protein interaction.
    Type: Application
    Filed: May 12, 2008
    Publication date: October 23, 2008
    Inventors: James B. Lorens, Todd R. Pray, Todd M. Kinsella, Mark K. Bennett
  • In vivo production of cyclic peptides for inhibiting protein-protein interaction
    Patent number: 7378248
    Abstract: The present invention relates to methods and compositions utilizing inteins to generate libraries of cyclic peptides in vivo. The prevent invention also relates to methods for inhibiting protein-protein interaction.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: May 27, 2008
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: James B. Lorens, Todd R. Pray, Todd M. Kinsella, Mark K. Bennett
  • Method for detecting oligermization of soluble amyloid beta oligomers
    Publication number: 20080113444
    Abstract: The present invention relates to the assay, analysis, and characterization of soluble amyloid beta oligomers, as well as the characterization of inhibitors of soluble amyloid beta oligomer assembly. In particular, the present invention is a method for detecting assembly of soluble amyloid beta oligomers via a combination of fluorescence resonance energy transfer (FRET) or time-resolved FRET and fluorescence polarization (FP).
    Type: Application
    Filed: October 16, 2007
    Publication date: May 15, 2008
    Inventor: Todd R. Pray
  • ASSAYS FOR IDENTIFYING UBIQUITIN AGENTS AND FOR IDENTIFYING AGENTS THAT MODIFY THE ACTIVITY OF UBIQUITIN AGENTS
    Publication number: 20080064117
    Abstract: Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying for agents that modulate the activity of such ubiquitin agents.
    Type: Application
    Filed: October 2, 2006
    Publication date: March 13, 2008
    Applicant: Rigel Pharmaceuticals, Inc.
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • Ubiquitin conjugation assays
    Patent number: 7022493
    Abstract: The invention relates to assays for measuring ubiquitin ligase activity and for identifying modulators of ubiquitin ligase enzymes.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: April 4, 2006
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
    Patent number: 6979551
    Abstract: Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying for agents that modulate the activity of such ubiquitin agents.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: December 27, 2005
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
    Patent number: 6919184
    Abstract: Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying for agents that modulate the activity of such ubiquitin agents.
    Type: Grant
    Filed: March 26, 2002
    Date of Patent: July 19, 2005
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • Ubiquitin ligase assay
    Patent number: 6737244
    Abstract: The invention relates to assays for measuring ubiquitin ligase activity and for identifying modulators of ubiquitin ligase enzymes.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: May 18, 2004
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • Assays and compositions for identifying agents that modulate the activity of deubiquitinating agents
    Publication number: 20040053324
    Abstract: Provided are methods and compositions for assaying for deubiquitinating agents that are enzymatic components of ubiquitin-mediated proteolysis and, their function, and agents that modulate the activity of such deubiquitinating agents.
    Type: Application
    Filed: August 30, 2002
    Publication date: March 18, 2004
    Inventors: Brian Wong, Todd R. Pray, Jianing Huang, David Anderson
  • Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
    Publication number: 20030108947
    Abstract: Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying for agents that modulate the activity of such ubiquitin agents.
    Type: Application
    Filed: May 20, 2002
    Publication date: June 12, 2003
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
    Publication number: 20030104474
    Abstract: Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying for agents that modulate the activity of such ubiquitin agents.
    Type: Application
    Filed: March 26, 2002
    Publication date: June 5, 2003
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray
  • Ubiquitin ligase assay
    Publication number: 20020042083
    Abstract: The invention relates to assays for measuring ubiquitin ligase activity and for identifying modulators of ubiquitin ligase enzymes.
    Type: Application
    Filed: April 3, 2001
    Publication date: April 11, 2002
    Applicant: RIGEL PHARMACEUTICALS, INC.
    Inventors: Sarkiz D. Issakani, Jianing Huang, Julie Sheung, Todd R. Pray