Patents by Inventor Tomio Yamakawa

Tomio Yamakawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11234984
    Abstract: The present invention relates to a solid dispersion containing a compound represented by General Formula (I): wherein R1 is an unsubstituted phenyl group or a phenyl group substituted with a substituent; the substituent is an alkyl group having 1 to 8 carbon atoms, an alkyl group having 1 to 8 carbon atoms substituted with a halogen atom, an alkoxy group having 1 to 8 carbon atoms, an alkoxycarbonyl group having 2 to 8 carbon atoms, a formyl group, a carboxyl group, a halogen atom, a phenyl group or a phenoxy group; R2 is a cyano group or a nitro group; R3 is a hydroxyl group; X is an oxygen atom or —S(O)n—; n is an integer of 0 to 2; Y is an oxygen atom or a sulfur atom, or a pharmaceutically acceptable salt thereof and a hypromellose derivative.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: February 1, 2022
    Assignees: Shizuoka Prefectural University Corporation, Nippon Chemiphar Co., Ltd.
    Inventors: Shigeru Itai, Shuji Noguchi, Yasunori Iwao, Masuharu Hirano, Takashi Ohta, Tomio Yamakawa
  • Publication number: 20200306251
    Abstract: The present invention relates to a solid dispersion containing a compound represented by General Formula (1): wherein R1 is an unsubstituted phenyl group or a phenyl group substituted with a substituent; the substituent is an alkyl group having 1 to 8 carbon atoms, an alkyl group having 1 to 8 carbon atoms substituted with a halogen atom, an alkoxy group having 1 to 8 carbon atoms, an alkoxycarbonyl group having 2 to 8 carbon atoms, a formyl group, a carboxyl group, a halogen atom, a phenyl group or a phenoxy group; R2 is a cyano group or a nitro group; R3 is a hydroxyl group; X is an oxygen atom or —S(O)n—; n is an integer of 0 to 2; Y is an oxygen atom or a sulfur atom, or a pharmaceutically acceptable salt thereof and a hypromellose derivative.
    Type: Application
    Filed: November 28, 2018
    Publication date: October 1, 2020
    Inventors: Shigeru Itai, Shuji Noguchi, Yasunori Iwao, Masuharu Hirano, Takashi Ohta, Tomio Yamakawa
  • Publication number: 20190255022
    Abstract: A wound-healing agent is provided by using a benzisoxazole compound represented by the following general formula (I), a tautomer, a stereoisomer, or a pharmaceutically acceptable salt of the compound, a solvate of any of the foregoing, or the like, which exerts a PPAR? agonist effect.
    Type: Application
    Filed: May 11, 2017
    Publication date: August 22, 2019
    Applicant: NIPPON CHEMIPHAR CO., LTD.
    Inventors: Toshitake HIRAI, Takaichi HAMANO, Tomio YAMAKAWA
  • Patent number: 9545658
    Abstract: There is provided a piercing apparatus in which the occurrence of an inner surface flaw in a hollow shell is suppressed. A piercing apparatus (10) according to an embodiment of the present invention is the piercing apparatus (10) which pierces a billet (18). The piercing apparatus (10) has a plug (14). The plug (14) has a through hole (30). The through hole (30) extends along the central axis, and allows the central portion of the billet (18) being pierced to pass therethrough.
    Type: Grant
    Filed: November 1, 2012
    Date of Patent: January 17, 2017
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Kazuhiro Shimoda, Tomio Yamakawa, Kouji Yamane, Yuji Inoue, Syusuke Shimooka, Kouji Muramatsu
  • Patent number: 9486845
    Abstract: An inner surface regulation tool includes a mandrel, a plug which is detachably connected to the mandrel, and a connection member which connects the plug and the mandrel by a magnetic force. One of the plug and the mandrel includes a column-shaped portion which extends in an axial direction of the one, and the other of the plug and the mandrel includes a joining hole which extends in an axial direction of the other and into which the column-shaped portion is inserted. In addition, the connection member is a permanent magnet which is attached to at least one of the column-shaped portion and the joining hole.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: November 8, 2016
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Kouji Yamane, Kazuhiro Shimoda, Tomio Yamakawa, Yuji Inoue
  • Patent number: 9308561
    Abstract: A method of producing a seamless metal pipe, which can suppress the occurrence of lamination defects, is provided. A method of producing a seamless metal pipe according to an embodiment of the present invention includes the steps of: heating a high alloy containing, by mass %, Cr: 20 to 30% and Ni: more than 22% and not more than 60% in a first heating furnace (S2); piercing-rolling the high alloy heated in the first heating furnace with a first piercing machine to produce a hollow shell (S3); heating the hollow shell in a second heating furnace (S4); and elongation-rolling the hollow shell heated in the second heating furnace with the first piercing machine or a second piercing machine which is different from the first piercing machine (S5).
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: April 12, 2016
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Kouji Yamane, Tomio Yamakawa, Kazuhiro Shimoda
  • Patent number: 9283600
    Abstract: A plug for hot pipe making includes a plurality of plug pieces which is attachable to and detachable from one another, and a connection member which connects the plug pieces by a magnetic force. One of the plug pieces connected to each other includes a column-shaped portion which extends in an axis direction of the plug for hot pipe making, and the other includes a joining hole which extends in the axis direction of the plug for hot pipe making and into which the column-shaped portion is inserted. The connection member is a permanent magnet which is attached to at least one of the column-shaped portion and the joining hole.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: March 15, 2016
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Kouji Yamane, Kazuhiro Shimoda, Tomio Yamakawa, Yuji Inoue
  • Patent number: 9254511
    Abstract: By using a piercing mill that includes a pusher on the entrance side, a plug on the exit side along a pass line, and a plurality of angled rolls as being provided around the plug so as face to each other, in the case where the maximum diameter of an unsound region consisting of center segregation and porosity in a cross section of a billet is d [mm], piercing-rolling is performed under the condition that the plug nose rolling reduction ratio (TDF) expressed by Formula (1) satisfies Formula (2). TDF=(Bd?D1)/Bd??(1) TDF??0.50×(d/Bd)+0.06??(2) In Formulae (1) and (2), Bd is the billet diameter [mm], and D1 is the opening [mm] between the angled rolls at the plug nose position. Thereby, when piercing-rolling is performed, the occurrence of an inner surface flaw attributable to the center segregation and porosity in the billet can be prevented reliably.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: February 9, 2016
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Kenichi Saitou, Kazuhiro Shimoda, Tomio Yamakawa
  • Patent number: 9221087
    Abstract: A method of producing a seamless metal pipe, which can suppress the occurrence of inner surface flaws, is provided. A method of producing a seamless metal pipe according to an embodiment of the present invention includes the steps of: heating a high alloy billet BL containing, by mass %, Cr: 20 to 30% and Ni: more than 22% and not more than 60% in a heating furnace F1 (S2); piercing-rolling the high alloy billet BL heated in the heating furnace F1 with a piercing machine P1 to produce a hollow shell (S3); cooling the hollow shell and then reheating the hollow shell in the heating furnace F1 (S4); and elongation-rolling the heated hollow shell with the piercing machine P1 (S5).
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: December 29, 2015
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Kouji Yamane, Tomio Yamakawa, Kazuhiro Shimoda
  • Publication number: 20150314346
    Abstract: An inner surface regulation tool includes a mandrel, a plug which is detachably connected to the mandrel, and a connection member which connects the plug and the mandrel by a magnetic force. One of the plug and the mandrel includes a column-shaped portion which extends in an axial direction of the one, and the other of the plug and the mandrel includes a joining hole which extends in an axial direction of the other and into which the column-shaped portion is inserted. In addition, the connection member is a permanent magnet which is attached to at least one of the column-shaped portion and the joining hole.
    Type: Application
    Filed: August 22, 2013
    Publication date: November 5, 2015
    Inventors: Kouji YAMANE, Kazuhiro SHIMODA, Tomio YAMAKAWA, Yuji INOUE
  • Publication number: 20150183010
    Abstract: A plug for hot pipe making includes a plurality of plug pieces which is attachable to and detachable from one another, and a connection member which connects the plug pieces by a magnetic force. One of the plug pieces connected to each other includes a column-shaped portion which extends in an axis direction of the plug for hot pipe making, and the other includes a joining hole which extends in the axis direction of the plug for hot pipe making and into which the column-shaped portion is inserted. The connection member is a permanent magnet which is attached to at least one of the column-shaped portion and the joining hole.
    Type: Application
    Filed: August 16, 2013
    Publication date: July 2, 2015
    Inventors: Kouji Yamane, Kazuhiro Shimoda, Tomio Yamakawa, Yuji Inoue
  • Patent number: 9034125
    Abstract: A method for manufacturing an Ni base alloy pipe stock comprises piercing and rolling a billet by use of Mannesmann piercing and rolling mill. The pipe stock has controlled amounts of C, Si, Mn, P, S, Cr, Ni, Mo, W, Cu, Al, N, with the balance being Fe. With the method, the following equations are satisfied, wherein values of TGBm, Psr and P? represented by the following equations (1) to (3) being not more than 1300, not more than 200 and not less than 0, respectively TGBm=1380?5000P?100S?4400C??(1), PsrNi+10(Mo+0.5W)+100N??(2), P?=(Ni?50)+10(N?0.1)?2(Cr?25)?5(Mo+0.5W?6)+12??(3), wherein each element symbol in the equations represents mass % of the element concerned.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: May 19, 2015
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Masaaki Igarashi, Kazuhiro Shimoda, Tomio Yamakawa, Hisashi Amaya Amaya
  • Patent number: 8863564
    Abstract: The present invention provides a lubricant composition for hot metal working which is capable of inhibiting generation of flaws on the surface of materials to be provided for hot metal working, and provides a method of hot metal working. The invention provides a lubricant composition for hot metal working comprising a plurality of glass frits respectively having different softening point from each other.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: October 21, 2014
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Kazuhiro Shimoda, Tomio Yamakawa, Kazutaka Asabe, Hirokazu Okada, Yasuyoshi Hidaka, Sumio Iida, Naoya Hirase, Kenji Takeuchi, Shuichi Akiyama
  • Patent number: 8846152
    Abstract: There is provided an antioxidant agent capable of preventing scale from being produced on the surface of a heated metallic starting material more effectively than the conventional antioxidant agent. The antioxidant agent according to the present invention contains a plurality of glass frits having different softening points and an inorganic compound having a melting point not higher than 600° C. The inorganic compound mainly softens in the low-temperature range of about 600° C. The plurality of glass frits mainly soften in the low-temperature range of about 600 to 1300° C. Therefore, the antioxidant agent covers the surface of metallic starting material in a broad temperature range, oxidizes the surface of metallic starting material, and prevents the production of scale.
    Type: Grant
    Filed: July 13, 2011
    Date of Patent: September 30, 2014
    Assignee: Nippon Steel & Sumitomo Metal Corporation
    Inventors: Kazuhiro Shimoda, Tomio Yamakawa, Koji Muramatsu, Yuji Inoue, Junichi Nishimori, Yasuyoshi Hidaka, Keishi Matsumoto, Takahisa Kato, Shuichi Akiyama
  • Publication number: 20140260494
    Abstract: There is provided a piercing apparatus in which the occurrence of an inner surface flaw in a hollow shell is suppressed. A piercing apparatus (10) according to an embodiment of the present invention is the piercing apparatus (10) which pierces a billet (18). The piercing apparatus (10) has a plug (14). The plug (14) has a through hole (30). The through hole (30) extends along the central axis, and allows the central portion of the billet (18) being pierced to pass therethrough.
    Type: Application
    Filed: November 1, 2012
    Publication date: September 18, 2014
    Inventors: Kazuhiro Shimoda, Tomio Yamakawa, Kouji Yamane, Yuji Inoue, Syusuke Shimooka, Kouji Muramatsu
  • Publication number: 20140250965
    Abstract: A method of producing a seamless metal pipe, which can suppress the occurrence of inner surface flaws, is provided. A method of producing a seamless metal pipe according to an embodiment of the present invention includes the steps of: heating a high alloy billet BL containing, by mass %, Cr: 20 to 30% and Ni: more than 22% and not more than 60% in a heating furnace F1 (S2); piercing-rolling the high alloy billet BL heated in the heating furnace F1 with a piercing machine P1 to produce a hollow shell (S3); cooling the hollow shell and then reheating the hollow shell in the heating furnace F1 (S4); and elongation-rolling the heated hollow shell with the piercing machine P1 (S5).
    Type: Application
    Filed: October 24, 2012
    Publication date: September 11, 2014
    Inventors: Kouji Yamane, Tomio Yamakawa, Kazuhiro Shimoda
  • Publication number: 20140245806
    Abstract: A method of producing a seamless metal pipe, which can suppress the occurrence of lamination defects, is provided. A method of producing a seamless metal pipe according to an embodiment of the present invention includes the steps of: heating a high alloy containing, by mass %, Cr: 20 to 30% and Ni: more than 22% and not more than 60% in a first heating furnace (S2); piercing-rolling the high alloy heated in the first heating furnace with a first piercing machine to produce a hollow shell (S3); heating the hollow shell in a second heating furnace (S4); and elongation-rolling the hollow shell heated in the second heating furnace with the first piercing machine or a second piercing machine which is different from the first piercing machine (S5).
    Type: Application
    Filed: October 24, 2012
    Publication date: September 4, 2014
    Applicant: Nippon Steel & Sumitomo Metal Corporation
    Inventors: Kouji Yamane, Tomio Yamakawa, Kazuhiro Shimoda
  • Patent number: 8815347
    Abstract: There is provided an antioxidant agent excellent in anti-dripping property and anti-peeling property. The antioxidant agent in accordance with the present invention contains a plurality of glass frits having different softening points, potter's clay, and bentonite and/or sepiolite. On account of the potter's clay, the antioxidant agent applied to the surface of a metallic starting material is less liable to drip down. Further, on account of the bentonite and/or sepiolite, the antioxidant agent is less liable to peel off the surface of the metallic starting material.
    Type: Grant
    Filed: July 13, 2011
    Date of Patent: August 26, 2014
    Assignee: Nippon Steel & Sumitomo Metal Corporation
    Inventors: Kazuhiro Shimoda, Keishi Matsumoto, Yasuyoshi Hidaka, Tomio Yamakawa, Shuichi Akiyama, Takahisa Kato
  • Patent number: 8783085
    Abstract: A method for straightening a tube by using an asymmetric roll, which has different diameters D1 (exit side), D2 (entry side) at relative maximum diameter portions, left and right roll shoulder portions, as a straightening roll of a straightener, wherein the roll shoulder having a smaller diameter is disposed to be located on the tube entry side. The straightening roll used therefor comprises roll shoulders 3a and 3b and a roll barrel portion 4, in which D1>D2 and 0.004?(D1?D2)/d?0.2 (d: outer diameter of tube to be straightened) are satisfied. Further, an aspect of the invention may define radii of curvatures of entry-side and exit-side shoulder potions in a section of the roll cut along a plane including the roll central axis, or a curve representing an outer surface of the roll barrel portion.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: July 22, 2014
    Assignee: Nippon Steel & Sumitomo Metal Corporation
    Inventors: Yoshiyuki Kuroiwa, Kouichi Kuroda, Tomio Yamakawa
  • Patent number: 8784581
    Abstract: An Fe—Ni alloy pipe stock containing, by mass %, C?0.04%, Si?0.50%, Mn: 0.01 to 6.0%, P?0.03%, S?0.01%, Cr: 20 to 30%, Ni: 30 to 45%, Mo: 0 to 10%, W: 0 to 20%, with Mo(%)+0.5W(%): more than 1.5% to not more than 10%, Cu: 0.01 to 1.5%, Al?0.01% and N: 0.0005 to 0.20%, and the balance being Fe, with 1440?6000P?100S?2000C?1300, Ni+10(Mo+0.5W)+100N?120, (Ni?35)+10(N?0.1)?2(Cr?25)?5(Mo+0.5W?3)+8?0, can be manufactured into a seamless pipe by use of a Mannesmann piercing and rolling mill because of its excellent inner surface properties. The resulting seamless pipe has excellent mechanical properties and moreover has excellent corrosion resistance in a sour gas environment.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: July 22, 2014
    Assignee: Nippon Steel & Sumitomo Metal Corporation
    Inventors: Masaaki Igarashi, Kazuhiro Shimoda, Tomio Yamakawa, Hisashi Amaya