Patents by Inventor Tomoharu TSUKADA

Tomoharu TSUKADA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220002277
    Abstract: It is intended to provide a novel compound or a salt thereof, or crystals of the compound or the salt, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl. [Solution] The present invention provides a pyridone derivative having a tetrahydropyranylmethyl group represented by the following formula (I) having various substituents, or a salt thereof, or crystals of the compound or the salt (wherein R1, R2, R3, R4, R5, W, X, Y, and Z are each as defined in the specification).
    Type: Application
    Filed: August 12, 2021
    Publication date: January 6, 2022
    Inventors: Noriyasu HAGINOYA, Takashi SUZUKI, Miho HAYAKAWA, Masahiro OTA, Tomoharu TSUKADA, Katsuhiro KOBAYASHI, Yosuke ANDO, Takeshi JIMBO, Koichi NAKAMURA
  • Patent number: 11208403
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: December 28, 2021
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Noriyasu Haginoya, Takashi Suzuki, Miho Hayakawa, Masahiro Ota, Tomoharu Tsukada, Katsuhiro Kobayashi, Yosuke Ando, Takeshi Jimbo, Koichi Nakamura
  • Publication number: 20200010458
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Application
    Filed: September 18, 2019
    Publication date: January 9, 2020
    Inventors: Noriyasu HAGINOYA, Takashi SUZUKI, Miho HAYAKAWA, Masahiro OTA, Tomoharu TSUKADA, Katsuhiro KOBAYASHI, Yosuke ANDO, Takeshi JIMBO, Koichi NAKAMURA
  • Patent number: 10442797
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: October 15, 2019
    Assignee: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Noriyasu Haginoya, Takashi Suzuki, Miho Hayakawa, Masahiro Ota, Tomoharu Tsukada, Katsuhiro Kobayashi, Yosuke Ando, Takeshi Jimbo, Koichi Nakamura
  • Publication number: 20180148436
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Application
    Filed: July 6, 2015
    Publication date: May 31, 2018
    Inventors: Noriyasu HAGINOYA, Takashi SUZUKI, Miho HAYAKAWA, Masahiro OTA, Tomoharu TSUKADA, Katsuhiro KOBAYASHI, Yosuke ANDO, Takeshi JIMBO, Koichi NAKAMURA
  • Publication number: 20170183329
    Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.
    Type: Application
    Filed: July 6, 2015
    Publication date: June 29, 2017
    Inventors: Noriyasu HAGINOYA, Takashi SUZUKI, Miho HAYAKAWA, Masahiro OTA, Tomoharu TSUKADA, Katsuhiro KOBAYASHI, Yosuke ANDO, Takeshi JIMBO, Koichi NAKAMURA
  • Patent number: 8946264
    Abstract: The present invention relates to a novel pyridine derivative or a pharmacologically acceptable ester thereof, or a pharmacologically acceptable salt of the derivative or ester, which has an excellent hypoglycemic effect or treats and/or prevents the onset of a disorder of carbohydrate or lipid metabolism or a disease mediated by peroxisome proliferator-activated receptor (PPAR) ?. A compound represented by the general formula (I): [wherein R represents a pyridyl group substituted with 1 to 3 group(s) independently selected from Substituent Group A, and Substituent Group A represents a halogen atom, a C1-C6 alkyl group and a C1-C6 alkoxy group] or a pharmacologically acceptable ester thereof, or a pharmacologically acceptable salt of the compound or ester.
    Type: Grant
    Filed: October 20, 2012
    Date of Patent: February 3, 2015
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Tsuyoshi Shinozuka, Tomoharu Tsukada, Kunihiko Fujii, Makoto Mori
  • Publication number: 20120029026
    Abstract: The present invention relates to a novel pyridine derivative or a pharmacologically acceptable ester thereof, or a pharmacologically acceptable salt of the derivative or ester, which has an excellent hypoglycemic effect or treats and/or prevents the onset of a disorder of carbohydrate or lipid metabolism or a disease mediated by peroxisome proliferator-activated receptor (PPAR) ?. A compound represented by the general formula (I): [wherein R represents a pyridyl group substituted with 1 to 3 group(s) independently selected from Substituent Group A, and Substituent Group A represents a halogen atom, a C1-C6 alkyl group and a C1-C6 alkoxy group] or a pharmacologically acceptable ester thereof, or a pharmacologically acceptable salt of the compound or ester.
    Type: Application
    Filed: April 15, 2011
    Publication date: February 2, 2012
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Tsuyoshi SHINOZUKA, Tomoharu TSUKADA, Kunihiko FUJII, Makoto MORI