Abstract: An object of the present invention is to provide, as a method for immobilizing a protein molecule, protein immobilization method and means in which orientation of a molecule to be immobilized can be controlled, the molecule can be stably immobilized without a complicated process and a chemical group used for immobilization does not affect the activity and the function of the protein. Specifically, the present invention relates to a method for immobilizing a molecule including the steps of forming a labeled molecule by attaching a label peptide sequence comprising a hydroxyl group-containing amino acid to a molecule; and bringing a molecule having a phenylboronic acid group into contact with the labeled molecule, to capture the labeled molecule by the molecule having a phenylboronic acid group.

Abstract: A cast piece surface temperature measuring device includes: a magnetic field exciting device which applies an AC magnetic field substantially perpendicular to a surface of a cast piece; a magnetic field detecting device which detects the AC magnetic field to detect a magnetic flux varied in response to a surface temperature of the cast piece; and a surface temperature deriving device which derives the surface temperature of the cast piece based on an induced electromotive force obtained by detecting the AC magnetic field by the magnetic field detecting device and a predetermined relation data.

Abstract: The present invention provides a bearing material that is excellent in durability and is capable of maintaining wear resistance over a long period of time. The bearing material of the present invention is a high wear-resistance bearing material 10 for being used under a humid environment comprising: a base body 12 made of a polymer material having a methylene group; and a polymer layer 30 covering a bearing surface 16 of the substrate 12, the polymer layer 30 comprising polymer chains which have a phosphorylcholine group and are grafted from the bearing surface 16, wherein a phosphoric index of the sliding surface 16 which is calculated by dividing a peak intensity of phosphate group in an infrared spectrum measured on the sliding surface by a peak intensity of the methylene group therein is not less than 0.28.

Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.

Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.

Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.

Abstract: In analyzing, fractionating, and culturing cells alive, operations can be more simply made in real time and culture can be performed while removing unnecessary cells from cultured cells for purification. Desired cells are also analyzed and fractionated from the cultured cells to increase the purity, recovery rate, and viability of the cells. A cell-adhesive photocontrollable base material is used in which light irradiation causes the bond dissociation of a photolabile group comprising an O-nitrobenzyl skeleton to irreversibly change the surface of the irradiated portion thereof from that of the cell-adhesive material to that of a non-cell-adhesive material. Cell images are detected and analyzed to obtain the positional information of desired cells. Based on this information, areas among cells and a cell-adhesive photocontrollable material are cut by second light irradiation.

Abstract: An object of the present invention is to provide, as a method for immobilizing a protein molecule, protein immobilization method and means in which orientation of a molecule to be immobilized can be controlled, the molecule can be stably immobilized without a complicated process and a chemical group used for immobilization does not affect the activity and the function of the protein. Specifically, the present invention relates to a method for immobilizing a molecule including the steps of forming a labeled molecule by attaching a label peptide sequence comprising a hydroxyl group-containing amino acid to a molecule; and bringing a molecule having a phenylboronic acid group into contact with the labeled molecule, to capture the labeled molecule by the molecule having a phenylboronic acid group.

Abstract: A cast piece surface temperature measuring device includes: a magnetic field exciting device which applies an AC magnetic field substantially perpendicular to a surface of a cast piece; a magnetic field detecting device which detects the AC magnetic field to detect a magnetic flux varied in response to a surface temperature of the cast piece; and a surface temperature deriving device which derives the surface temperature of the cast piece based on an induced electromotive force obtained by detecting the AC magnetic field by the magnetic field detecting device and a predetermined relation data.

Abstract: The present invention provides a previously unattainable compact and high thrust electromagnetic stirrer coil, that is, an electromagnetic stirrer coil for stirring molten steel in a mold by electromagnetic force, in which electromagnetic stirrer coil a space factor of the yoke sectional area (?) with respect to an inside area in a vertical cross-section of said electromagnetic stirrer coil is 0.5 to 0.9 and a yoke width B is 100 mm to 300 mm. Preferably, a magnetomotive force F of said electromagnetic stirrer coil divided by the yoke width B, that is, a value of F/B, is 800 kAT/m or more.

Abstract: The present invention provides a previously unattainable compact and high thrust electromagnetic stirrer coil, that is, an electromagnetic stirrer coil for stirring molten steel in a mold by electromagnetic force, in which electromagnetic stirrer coil a space factor of the yoke sectional area (-) with respect to an inside area in a vertical cross-section of said electromagnetic stirrer coil is 0.5 to 0.9 and a yoke width B is 100 mm to 300 mm. Preferably, a magnetomotive force F of said electromagnetic stirrer coil divided by the yoke width B, that is, a value of F/B, is 800 kAT/m or more.

Abstract: The present invention provides a tissue adhesion prevention material preparable at an affected area at the time of surgical procedure by producing a three-dimensional polymeric structure having a flexible structure and high solute permeability in a medium comprising water as the main component under mild conditions appropriate for body tissue components (i.e., at ordinary temperature and pressure) without conducting a chemical reaction or employing a physical procedure such as heating or light or radiation irradiation. This makes it possible to provide a tissue adhesion prevention material and a joint contracture prevention materials, which can effectively prevent postoperative adhesion of a tissue in the affected area to the surrounding tissue and contracture of the movable part of a joint.

Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.

Abstract: An artificial joint member made of a polymeric material including a portion made of a polymeric substance has a sliding surface composed of a polymer having phosphoryl choline groups. With such an arrangement, the artificial joint member is provided with a sliding part capable of keeping a satisfactory lubricating state for a long time.

Abstract: Non-oriented electrical steel sheet superior in core loss characterized by containing, by mass %, C: 0.01% or less, Si: 0.1% to 7.0%, Al: 0.1% to 3.0%, Mn: 0.1% to 2.0%, N: 0.005% or less, Ti: 0.02% or less, REM: 0.05% or less, S: 0.005% or less, O: 0.005% or less, and a balance of iron and unavoidable impurities and having a mass % of S shown by [S], a mass % of O shown by [O], a mass % of REM shown by [REM], a mass % of Ti shown by [Ti], and a mass % of N shown by [N] satisfying [Formula 1] and [Formula 2]: [REM]2×[O]2×[S]?1×10?15??[Formula 1] ([REM]2×[O]2×[S])÷([Ti]×[N])?1×10?10??[Formula 2].

Abstract: The present invention provides a bearing material that is excellent in durability and is capable of maintaining wear resistance over a long period of time. The bearing material of the present invention is a high wear-resistance bearing material 10 for being used under a humid environment comprising: a base body 12 made of a polymer material having a methylene group; and a polymer layer 30 covering a bearing surface 16 of the substrate 12, the polymer layer 30 comprising polymer chains which have a phosphorylcholine group and are grafted from the bearing surface 16, wherein a phosphoric index of the sliding surface 16 which is calculated by dividing a peak intensity of phosphate group in an infrared spectrum measured on the sliding surface by a peak intensity of the methylene group therein is not less than 0.28.

Abstract: Non-oriented electrical steel sheet superior in core loss characterized by containing, by mass %, C: 0.01% or less, Si: 0.1% to 7.0%, Al: 0.1% to 3.0%, Mn: 0.1% to 2.0%, N: 0.005% or less, Ti: 0.02% or less, REM: 0.05% or less, S: 0.005% or less, O: 0.

Abstract: The present invention provides a previously unattainable compact and high thrust electromagnetic stirrer coil, that is, an electromagnetic stirrer coil for stirring molten steel in a mold by electromagnetic force, in which electromagnetic stirrer coil a space factor of the yoke sectional area (?) with respect to an inside area in a horizontal cross-section of said electromagnetic stirrer coil is 0.5 to 0.9 and a yoke width B is 100 mm to 300 mm. Preferably, a magnetomotive force F of said electromagnetic stirrer coil divided by the yoke width B, that is, a value of F/B, is 800 kAT/m2 or more.

Abstract: An agent for fixing (a) substance(s), which can fix various substances to be fixed on a substrate via covalent bonds and which has an excellent effect for the prevention of non-specific adsorption is disclosed. A polymer containing a plurality of phosphorylcholine groups and photoreactive groups in one molecule is used. The polymer binds to the substrate and to the substance to be fixed via the photoreactive groups, thereby the substance to be fixed is bound to the substrate via covalent bonds through the polymer, and non-specific adsorption is effectively prevented by the phosphorylcholine groups. Further, an agent for fixing (a) substance(s) for fixing the substance on a substrate, comprising a nonionic water-soluble macromolecule having at least 2 photoreactive groups in one molecule was also provided.

Abstract: An artificial joint member made of a polymeric material including a portion made of a polymeric substance has a sliding surface composed of a polymer having phosphoryl choline groups. With such an arrangement, the artificial joint member is provided with a sliding part capable of keeping a satisfactory lubricating state for a long time.