Patents by Inventor Tong Geon Lee
Tong Geon Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240084320Abstract: Described are CRISPR constructs and systems that can be used to generate brachytic Solanaceae plants rapidly and efficiently. Also described are methods of introducing a brachytic phenotype into a Solanaceae plant having one or more other desired traits using the described CRISPR constructs and systems to generate loss of function mutations in one or more brachytic loci in the plant.Type: ApplicationFiled: January 5, 2022Publication date: March 14, 2024Inventor: Tong Geon LEE
-
Patent number: 11268102Abstract: Molecular markers associated with Solanaceae brachytic locus, methods of their use, and compositions having one or more marker loci are provided. Methods comprising detecting at least one marker locus, detecting a haplotype, and/or detecting a marker profile are provided. Methods and compositions are described for breeding tomato plants containing quantitative trait loci that are associated with brachytic phenotype and monitoring introgression of brachytic locus. Methods and compositions are also described for modifying a brachytic locus using CRISPR/Cas.Type: GrantFiled: May 15, 2019Date of Patent: March 8, 2022Assignee: University of Florida Research Foundation, IncorporatedInventors: Tong Geon Lee, Samuel Forrest Hutton
-
Publication number: 20220064664Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.Type: ApplicationFiled: May 3, 2021Publication date: March 3, 2022Inventors: Andrew Bent, Matthew Hudson, Brian Diers, Sara Melito, David Cook, Teresa Hughes, Adam Bayless, Jianping Wang, Tong Geon Lee, Xiaoli Guo
-
Patent number: 10995342Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.Type: GrantFiled: March 15, 2013Date of Patent: May 4, 2021Assignees: WISCONSIN ALUMNI RESEARCH FOUNDATION, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLNOISInventors: Andrew Bent, Matthew Hudson, Brian Diers, Sara Melito, David Cook, Teresa Hughes, Adam Bayless, Jianping Wang, Tong Geon Lee, Xiaoli Guo
-
Patent number: 10808260Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.Type: GrantFiled: November 23, 2016Date of Patent: October 20, 2020Assignees: Wisconsin Alumni Research Foundation, The Board of Trustees of the University of IllinoisInventors: Andrew Farmer Bent, Matthew Hudson, Brian Diers, Sara Melito, David Edward Cook, Teresa Hughes, Adam Bayless, Jianping Wang, Tong Geon Lee, Xiaoli Guo
-
Publication number: 20200045901Abstract: Molecular markers associated with Solanaceae brachytic locus, methods of their use, and compositions having one or more marker loci are provided. Methods comprising detecting at least one marker locus, detecting a haplotype, and/or detecting a marker profile are provided. Methods and compositions are described for breeding tomato plants containing quantitative trait loci that are associated with brachytic phenotype and monitoring introgression of brachytic locus. Methods and compositions are also described for modifying a brachytic locus using CRISPR/Cas.Type: ApplicationFiled: May 15, 2019Publication date: February 13, 2020Inventors: Tong Geon Lee, Samuel Forrest Hutton
-
Patent number: 10337072Abstract: Described herein are methods of measuring, in a genomic sample from an individual, the relative frequency of a target sequence (that is, its copy number) with respect to a control sequence of known copy number at a different genomic locus in the same genome, wherein the target and control sequences differ by at least one single nucleotide variation (SNV). These methods involve both the target sequence and the control sequence in a single reaction/container, using a pair of primers that prime amplification of both the target sequence and the control sequence, or a single downstream primer and two upstream primers (that differs only at the position of the SNV between the target and control sequences), and measuring the abundance of each of the target sequence and the control sequence using SNV-specific labeled probes or primers, or a melting curve analysis that distinguishes between the amplified control and target sequences. The methods are exemplified with various different amplifications process.Type: GrantFiled: January 8, 2016Date of Patent: July 2, 2019Assignee: The Board of Trustees of the University of IllinoisInventors: Matthew E. Hudson, Brian W. Diers, Tong Geon Lee
-
Publication number: 20180112230Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.Type: ApplicationFiled: November 23, 2016Publication date: April 26, 2018Inventors: Andrew Farmer Bent, Matthew Hudson, Brian Diers, Sara Melito, David Edward Cook, Teresa Hughes, Adam Bayless, Jianping Wang, Tong Geon Lee, Xiaoli Guo
-
Publication number: 20160265070Abstract: Described herein are methods of measuring, in a genomic sample from an individual, the relative frequency of a target sequence (that is, its copy number) with respect to a control sequence of known copy number at a different genomic locus in the same genome, wherein the target and control sequences differ by at least one single nucleotide variation (SNV). These methods involve both the target sequence and the control sequence in a single reaction/container, using a pair of primers that prime amplification of both the target sequence and the control sequence, or a single downstream primer and two upstream primers (that differs only at the position of the SNV between the target and control sequences), and measuring the abundance of each of the target sequence and the control sequence using SNV-specific labeled probes or primers, or a melting curve analysis that distinguishes between the amplified control and target sequences. The methods are exemplified with various different amplifications process.Type: ApplicationFiled: January 8, 2016Publication date: September 15, 2016Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Matthew E. Hudson, Brian W. Diers, Tong Geon Lee
-
Publication number: 20130305410Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.Type: ApplicationFiled: March 15, 2013Publication date: November 14, 2013Inventors: Andrew Farmer Bent, Matthew Hudson, Brian Diers, Sara Melito, David Edward Cook, Teresa Hughes, Adam Bayless, Jianping Wang, Tong Geon Lee, Xiaoli Guo
-
Publication number: 20130254945Abstract: Provided herein are isolated nucleic acid molecules representing a genetically defined region of the genome of the aphid resistant soybean plant (Glycine max) cultivar PI 200538 that confers resistance to soybean aphid (Aphis glycines). Within the region is a gene encoding the aphid resistance protein Rag2. Also provided herein are methods for conferring aphid resistance on a plant or enhancing aphid resistance in a plant by transforming it to contain and express such nucleic acid sequences encoding Rag2 aphid resistance or introgressing DNA encoding the trait into the plant by plant breeding. Further provided are polymorphic markers useful for identifying plant germplasm containing aphid resistance, and methods for using such markers.Type: ApplicationFiled: September 6, 2012Publication date: September 26, 2013Applicants: United States of America as represented by the Secretary of Agriculture, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Ki-Seung Kim, Curtis B. Hill, Glen L. Hartman, David L. Hyten, Matthew E. Hudson, Brian W. Diers, Tong Geon Lee