Patents by Inventor Toshiharu Abe

Toshiharu Abe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170136089
    Abstract: The present invention includes compositions and methods that take advantage of MFG-E8's role as a homeostatic regulator of osteoclasts for treating a bone disorder or regulating osteoclast activation. In one aspect, the invention includes a composition comprising an effective amount of milk fat globule-EGF factor 8 (MFG-E8) formulated for local administration and a pharmaceutically acceptable carrier or adjuvant. In another aspect, a method is included for regulating osteoclast activation and inhibiting bone loss at a target site comprising locally administering an effective amount of milk fat globule-EGF factor 8 (MFG-E8) to the target site.
    Type: Application
    Filed: May 12, 2015
    Publication date: May 18, 2017
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: George HAJISHENGALLIS, Toshiharu ABE, Jieun SHIN
  • Patent number: 8696834
    Abstract: A method for suppressing shock and storage cracking when manufacturing seamless steel pipes comprises hot piercing and hot rolling a billet consisting of, by mass percent controlled amounts of C, Si, Mn, Cr, Mo, Ti, and Al, with the balance being Fe and impurities of Ni, P, S, N, and O also in controlled amounts. Further heat treatment is performed, wherein a hot rolled steel pipe is direct quenched from a temperature of not lower than the Ar3 transformation point and the pipe is then subjected to heat treatment at a temperature of not lower than 450° C. and not higher than the Ac1 transformation point in heat treatment equipment for performing direct quenching. The steel pipe subjected to the heat treatment is reheated, quenched from a temperature of not lower than the Ac3 transformation point, and tempered at a temperature of not higher than the Ac1 transformation point.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: April 15, 2014
    Assignee: Nippon Steel & Sumitomo Metal Corporation
    Inventors: Keiichi Kondo, Toshiharu Abe, Kunio Kondo, Yuichi Yano, Yuji Arai
  • Publication number: 20120042992
    Abstract: A method for suppressing shock and storage cracking when manufacturing seamless steel pipes comprises hot piercing and hot rolling a billet consisting of, by mass percent controlled amounts of C, Si, Mn, Cr, Mo, Ti, and Al, with the balance being Fe and impurities of Ni, P, S, N, and O also in controlled amounts. Further heat treatment is performed, wherein a hot rolled steel pipe is direct quenched from a temperature of not lower than the Ar3 transformation point and the pipe is then subjected to heat treatment at a temperature of not lower than 450° C. and not higher than the Ac1 transformation point in heat treatment equipment for performing direct quenching. The steel pipe subjected to the heat treatment is reheated, quenched from a temperature of not lower than the Ac3 transformation point, and tempered at a temperature of not higher than the Ac1 transformation point.
    Type: Application
    Filed: September 20, 2011
    Publication date: February 23, 2012
    Applicant: SUMITOMO METAL INDUSTRIES, LTD.
    Inventors: Keiichi KONDO, Toshiharu ABE, Kunio KONDO, Yuichi YANO, Yuji ARAI
  • Patent number: 7799149
    Abstract: An oil country tubular good for expansion according to the invention is expanded in a well. The oil country tubular good for expansion has a composition containing, in percentage by mass, 0.05% to 0.08% C, at most 0.50% Si, 0.80% to 1.30% Mn, at most 0.030% P, at most 0.020% S, 0.08% to 0.50% Cr, at most 0.01% N, 0.005% to 0.06% Al, at most 0.05% Ti, at most 0.50% Cu, and at most 0.50% Ni, and the balance consisting of Fe and impurities, and a structure having a ferrite ratio of at least 80%. The oil country tubular good for expansion has a yield strength in the range from 276 MPa to 379 MPa and a uniform elongation of at least 16%. Therefore, the oil country tubular good according to the invention has a high pipe expansion characteristic.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: September 21, 2010
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Taro Ohe, Keiichi Nakamura, Hideki Takabe, Toshiharu Abe, Tomoki Mori, Masakatsu Ueda
  • Publication number: 20090098403
    Abstract: A low alloy steel is provided for oil country tubular goods with a yield strength between 654 MPa and 757 MPa, and possessing excellent resistance to HIC and SSC in high-pressure hydrogen sulfides environment, and comprising, by mass %: 0.10 to 0.60% C; 0.05 to 0.5% Si; 0.05 to 3.0% Mn; 0.025% or less P; 0.010% or less S; 0.005 to 0.10% Al; 0.01% or less O (oxygen); 3.0% or less Cr; and 3.0% or less Mo, wherein the amount of Cr and Mo content is 1.2% or more, with the balance being Fe and impurities, and the number of nonmetallic inclusions whose major axis is 10 ?m or more is 10 per square millimeter in the inspected cross section. The present invention provides a low alloy steel for oil country tubular goods possessing excellent resistance to sulfide stress cracking, and a seamless steel pipe.
    Type: Application
    Filed: September 16, 2008
    Publication date: April 16, 2009
    Inventors: Tomohiko Omura, Yuji Arai, Kuniaki Tomomatsu, Toshiharu Abe
  • Publication number: 20090047166
    Abstract: A low alloy steel comprising, by mass %, C: 0.10 to 0.20%, Si: 0.05 to 1.0%, Mn: 0.05 to 1.5%, Cr: 1.0 to 2.0%, Mo: 0.05 to 2.0%, Al: 0.10 % or less and Ti: 0.002 to 0.05%, and with a Ceq value obtained by the following formula (1) of 0.65 or more, with the balance being Fe and impurities, wherein in the impurities, P is 0.025% or less, S is 0.010% or less, N is 0.007% or less, and B is less than 0.0003%, and the number per unit area of M23C6 type precipitates (M: a metal element) whose grain diameter is 1 ?m or more is 0.1/mm2 or less. This invention provides a low alloy steel possessing both hardenability and toughness and improves the resistance to sulfide stress corrosion cracking. Ceq=C+(Mn/6)+(Cr+Mo+V)/5 ??formula (1) where C, Mn, Cr, Mo and V in the formula (1) denote the mass % of respective elements.
    Type: Application
    Filed: October 1, 2008
    Publication date: February 19, 2009
    Inventors: Kuniaki Tomomatsu, Tomohiko Omura, Yuji Arai, Toshiharu Abe
  • Publication number: 20090032150
    Abstract: An oil country tubular good for expansion according to the invention is expanded in a well. The oil country tubular good for expansion has a composition containing, in percentage by mass, 0.05% to 0.08% C, at most 0.50% Si, 0.80% to 1.30% Mn, at most 0.030% P, at most 0.020% S, 0.08% to 0.50% Cr, at most 0.01% N, 0.005% to 0.06% Al, at most 0.05% Ti, at most 0.50% Cu, and at most 0.50% Ni, and the balance consisting of Fe and impurities, and a structure having a ferrite ratio of at least 80%. The oil country tubular good for expansion has a yield strength in the range from 276 MPa to 379 MPa and a uniform elongation of at least 16%. Therefore, the oil country tubular good according to the invention has a high pipe expansion characteristic.
    Type: Application
    Filed: September 29, 2008
    Publication date: February 5, 2009
    Inventors: Taro Ohe, Keiichi Nakamura, Hideki Takabe, Toshiharu Abe, Tomoki Mori, Masakatsu Ueda
  • Publication number: 20060231168
    Abstract: Disclosed are seamless steel tubes for oil well use, comprising C: 0.14-0.35%, Si: 0.05-1.0%, Mn: 0.05-2.0%, Cr: 0.05-1.5%, Mo: 0.05-2.0%, Ti: 0-0.05%, V: 0-0.1%, and Al: not less than 0.010%, wherein the concentration product by Al and N content, corrected by Ti and V, is within the range of 0.00001 to 0.00050, and the residuals are Fe and impurities including P: 0.025% or less, and S: 0.010% or less. Ti, V, Nb, or B is preferably contained to enhance the quench hardenability as well as the resistance to sulfide stress corrosion cracking, and further Ca, Mg and/or REM is preferably contained to improve the shape of non-metallic inclusions, enhancing the resistance to sulfide stress corrosion cracking. Thus, said tubes by the invention can be produced by efficient means realizing energy savings, and widely used as ones having excellent stability in mechanical strength.
    Type: Application
    Filed: March 24, 2006
    Publication date: October 19, 2006
    Inventors: Keiichi Nakamura, Hajime Osako, Nobutoshi Murao, Toshiharu Abe
  • Patent number: 6958099
    Abstract: A steel material and a steel pipe made by using the same are provided which are to be used in severe oil well environments. Such a highly tough oil well steel pipe can be produced by rolling the base material, quenching the rolling product from the austenite region and tempering the same so that the relationship between the content of Mo [Mo] in the carbides precipitated at austenite grain boundaries and the austenite grain size (according to ASTM E 112) can be defined by the formula (a) given below. In this manner, steel pipes suited for use even under oil well environments becoming more and more severe can be produced while satisfying the requirements that the cost should be rationalized, the productivity improved and energy saved.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: October 25, 2005
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Shigeru Nakamura, Kaori Kawano, Tomohiko Omura, Toshiharu Abe
  • Patent number: 6692592
    Abstract: A method for manufacturing a high Cr system seamless steel pipe having a high inside surface quality with a high efficiency and at a reduced production cost is provided. An initial material including Cr at a content of 10 to 20%, and impurities S and P at respective contents of not more than 0.050% is used to form a finished pipe, and when using parameters, the total soaking period &Sgr;t1 (hours) for soaking the initial material to form a primary pipe material as a billet or bloom and the total soaking period &Sgr;t2 (hours) for soaking the primary pipe material, a finished pipe is formed at a heating temperature of 1,200° C. under the condition that the following equation (b) is satisfied: F = f + 0.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: February 17, 2004
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Shigeru Kidani, Koichi Ikeda, Toshiharu Abe
  • Publication number: 20030178111
    Abstract: A steel material and a steel pipe made by using the same are provided which are to be used in severe oil well environments. Such a highly tough oil well steel pipe can be produced by rolling the base material, quenching the rolling product from the austenite region and tempering the same so that the relationship between the content of Mo [Mo] in the carbides precipitated at austenite grain boundaries and the austenite grain size (according to ASTM E 112) can be defined by the formula (a) given below. In this manner, steel pipes suited for use even under oil well environments becoming more and more severe can be produced while satisfying the requirements that the cost should be rationalized, the productivity improved and energy saved.
    Type: Application
    Filed: April 22, 2003
    Publication date: September 25, 2003
    Inventors: Shigeru Nakamura, Kaori Kawano, Tomohiko Omura, Toshiharu Abe
  • Publication number: 20030127162
    Abstract: A method for manufacturing a high Cr system seamless steel pipe having a high inside surface quality with a high efficiency and at a reduced production cost is provided. An initial material including Cr at a content of 10 to 20%, and impurities S and P at respective contents of not more than 0.050% is used to form a finished pipe, and when using parameters, the total soaking period &Sgr;t1 (hours) for soaking the initial material to form a primary pipe material as a billet or bloom and the total soaking period &Sgr;t2 (hours) for soaking the primary pipe material, a finished pipe is formed at a heating temperature of 1,200° C. under the condition that the following equation (b) is satisfied: 1 F = f + 0.6 × ( 1 - 1 e ∑   ⁢ t1 ) + 0.8 × ( 1 - 1 e ∑ t2 ) > - 9.
    Type: Application
    Filed: February 11, 2003
    Publication date: July 10, 2003
    Inventors: Shigeru Kidani, Koichi Ikeda, Toshiharu Abe