Patents by Inventor Toshihiko Nishioka

Toshihiko Nishioka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090214629
    Abstract: A method for efficiently transferring a gene to a target cell is provided. A method of transferring a gene to a target cell, including adding or administering a positively charged complex (A) composed of the gene and a cationic substance and gas-filled microparticles (B) to a target cell-containing composition or a living body and then exposing the target cell-containing composition or the living body to a low-frequency ultrasound.
    Type: Application
    Filed: May 26, 2005
    Publication date: August 27, 2009
    Applicant: Mebiopharm Co., Ltd
    Inventors: Kazuo Maruyama, Tomoko Takizawa, Kosuke Hagisawa, Toshihiko Nishioka, Hironobu Yanagie
  • Publication number: 20090110643
    Abstract: Gas-filled liposomes that are useful for ultrasonography and ultrasound therapy are provided. A method of producing the gas-filled liposomes, including filling the void space in a sealed container containing a liposome suspension in a volume amounting to 20 to 80% of the inner capacity thereof with a fluoride gas or a nitrogen gas, and subjecting the container to an ultrasonication.
    Type: Application
    Filed: May 23, 2005
    Publication date: April 30, 2009
    Applicant: MEBIOPHARM CO., LTD.
    Inventors: Kazuo Maruyama, Tomoko Takizawa, Kosuke Hagisawa, Toshihiko Nishioka, Hironobu Yanagie
  • Patent number: 4397013
    Abstract: A cantilever for use in supporting a stylus tip of a phonograph pickup is disclosed, which consists of a pipe of a ceramic material composed mainly of aluminum oxide. This cantilever is light weight and has a high Young's modulus. When this cantilever is attached to a phonograph pickup, reproduction loss can be remarkably reduced over all the reproduction frequency range and sounds can be reproduced having good response characteristics.
    Type: Grant
    Filed: February 23, 1979
    Date of Patent: August 2, 1983
    Assignees: Kyoto Ceramic Co., Ltd., Nagaoka & Co., Ltd.
    Inventors: Tadayoshi Shiomi, Toshihiko Nishioka