Patents by Inventor Toshihiro Kogure

Toshihiro Kogure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190350840
    Abstract: A microneedle device of the present invention comprises a substrate, microneedles disposed on the substrate, and a coating formed on the microneedles, wherein the coating comprising dexmedetomidine or a pharmaceutically acceptable salt thereof and isoproterenol or a pharmaceutically acceptable salt thereof. Using said microneedle device, a fast increase rate of dexmedetomidine concentration in plasma after application of the microneedle device is achieved.
    Type: Application
    Filed: December 25, 2017
    Publication date: November 21, 2019
    Inventors: Ryota HORI, Toshihiro KOGURE, Seiji TOKUMOTO, Shinpei NISHIMURA
  • Patent number: 8771726
    Abstract: The present subject matter provides a nail patch comprising a backing layer and a pressure-sensitive adhesive layer disposed on at least one side of the backing layer, wherein the pressure-sensitive adhesive layer comprises a pressure-sensitive adhesive base, terbinafine and/or a pharmacologically acceptable salt thereof, and sodium acetate and/or sorbitan monolaurate as a solubilizer.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: July 8, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc
    Inventors: Arata Toshimitsu, Naoko Matsuda, Toshihiro Kogure, Kazuya Ishida
  • Patent number: 8574621
    Abstract: The present invention provides an adhesive patch for the treatment of tinea unguium intended to be applied once a day, comprising terbinafine and/or a pharmacologically acceptable salt thereof in an amount of 3 mg/cm2, wherein the adhesive patch is used so that the terbinafine concentration in nails may be 295±127 ng/mg and the terbinafine concentration in plasma may be 23 pg/mL or less, 8 weeks after the start of application, per cm2 of the patch size.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: November 5, 2013
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Arata Toshimitsu, Naoko Fujita, Toshihiro Kogure
  • Publication number: 20120302644
    Abstract: The present invention provides an adhesive patch for the treatment of tinea unguium intended to be applied once a day, comprising terbinafine and/or a pharmacologically acceptable salt thereof in an amount of 3 mg/cm2, wherein the adhesive patch is used so that the terbinafine concentration in nails may be 295±127 ng/mg and the terbinafine concentration in plasma may be 23 pg/mL or less, 8 weeks after the start of application, per cm2 of the patch size.
    Type: Application
    Filed: February 7, 2011
    Publication date: November 29, 2012
    Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Arata Toshimitsu, Naoko Fujita, Toshihiro Kogure
  • Publication number: 20090324696
    Abstract: The present subject matter provides a nail patch comprising a backing layer and a pressure-sensitive adhesive layer disposed on at least one side of the backing layer, wherein the pressure-sensitive adhesive layer comprises a pressure-sensitive adhesive base, terbinafine and/or a pharmacologically acceptable salt thereof, and sodium acetate and/or sorbitan monolaurate as a solubilizer.
    Type: Application
    Filed: July 6, 2007
    Publication date: December 31, 2009
    Inventors: Arata Toshimitsu, Naoko Matsuda, Toshihiro Kogure, Kazuya Ishida
  • Publication number: 20060240288
    Abstract: A titania nanosheet alignment thin film whose main components are silica and titania, wherein titania nanosheets of layer structure having a nanometer order size are dispersed on a surface thereof. The titania nanosheet alignment thin film not only exhibits high photocatalytic activity but also can maintain excellent ultrahydrophilic and anti-fogging properties for a prolonged period of time. Further, there are provided a process for producing the same and an article including the titania nanosheet alignment thin film.
    Type: Application
    Filed: January 24, 2006
    Publication date: October 26, 2006
    Inventors: Tsutomu Minami, Toshihiro Kogure, Masahiro Tatsumisago, Kiyoharu Tadanaga, Atsunori Matsuda
  • Publication number: 20050042375
    Abstract: A titania nanosheet alignment thin film whose main components are silica and titania, wherein titania nanosheets of layer structure having a nanometer order size are dispersed on a surface thereof. The titania nanosheet alignment thin film not only exhibits high photocatalytic activity but also can maintain excellent ultrahydrophilic and anti-fogging properties for a prolonged period of time. Further, there are provided a process for producing the same and an article including the titania nanosheet alignment thin film.
    Type: Application
    Filed: February 28, 2003
    Publication date: February 24, 2005
    Applicant: Japan Science and Technology Agency
    Inventors: Tsutomu Minami, Toshihiro Kogure, Masahiro Tatsumisago, Kiyoharu Tadanaga, Atsunori Matsuda
  • Patent number: 5559084
    Abstract: Disclosed are a composition and a method of preparing a composition of the formula R.sub.2 Q.sub.4 Cu.sub.7 O.sub.x, wherein R is a rare-earth ion or a mixture of rare earth ions, and Q is Ba, or Ba combined with either Sr or Ca or both Sr and Ca. Such compositions have a unique crystalline structure and are superconducting oxides.
    Type: Grant
    Filed: May 28, 1991
    Date of Patent: September 24, 1996
    Assignee: Massachusetts Institute of Technology
    Inventors: John B. Vandersande, Gregory J. Yurek, Toshihiro Kogure
  • Patent number: 5427867
    Abstract: A substrate used for magnetic disk comprising s non-magnetic support in which a material for forming pits is formed on the surface, wherein the material for forming the surface pits comprises a low melting metal and has an island structure discontinuous in the direction within the plane at the surface of the non-magnetic support, thereby enabling to produce a magnetic disk of excellent magnetic property at high productivity, as well as a magnetic recording medium using such a substrate.
    Type: Grant
    Filed: June 3, 1994
    Date of Patent: June 27, 1995
    Assignee: Nippon Sheet Glass Co., Ltd.
    Inventors: Toshihiro Kogure, Tomoyasu Shimizu, Toshiyuki Sato, Shinya Katayama