Abstract: [Object] To provide a fusion protein of an antibody that recognizes cancer cells and a mutant streptavidin, which is for use in the treatment or diagnosis of cancer. [Means for Solution] A fusion protein comprising a protein-recognizing substance and the amino acid sequence as set forth in SEQ ID NO: 19 that is fused with the protein-recognizing substance.

Abstract: It is an object of the present invention to provide a fusion protein of an antibody that recognizes cancer cells and a mutant streptavidin, which is for use in the treatment or diagnosis of cancer. According to the present invention, provided is a fusion protein having the amino acid sequence as set forth in SEQ ID NO: 2 or SEQ ID NO: 7, a linker sequence, and the amino acid sequence as set forth in SEQ ID NO: 1 (provided that the amino acid sequence portion consisting of 6 histidine residues at the C-terminus thereof may be partially or entirely deleted), from the N-terminal side to the C-terminal side, in this order.

Abstract: The present invention addresses the problem of providing a medicinal composition and a drug combination by which nonalcoholic fatty liver disease and nonalcoholic steatohepatitis can be prevented and/or treated. The present invention provides a combination of a peroxisome proliferator-activated receptor (PPAR) ? agonist with a sodium glucose cotransporter 2 (SGLT2) inhibitor, which is to be used for preventing and/or treating nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.

Abstract: It is an object of the present invention to provide a conjugate of a biotin-modified dimer and a phthalocyanine dye, which is used in photoimmunotherapy. The present invention provides a conjugate of a compound represented by the following formula (1) or a salt thereof and a phthalocyanine dye: wherein the meaning of each of symbols is as defined in the specification.

Abstract: A vehicle front lighting apparatus includes a lighting device array in which multiple lighting devices are connected in series, multiple bypass circuits, multiple switch elements, a lighting intensity detector, a lighting schedule generator, a lighting controller, a current value detector, a voltage value controller, a detector, and a disconnection determiner. When there is the switch element to be brought into a closed state during a prohibition period from a lighting timing to a post-lighting timing, the lighting schedule generator changes a timing at which the switch element is brought into the closed state outside the prohibition period. The disconnection determiner determines that a disconnection has occurred in any of the bypass circuits when the number of switch elements detected at the post-lighting timing does not match a voltage value.

Abstract: In a vehicle front lighting apparatus, the number of switch elements brought into an opened state and an applied voltage value is detected every time a predetermined detection condition is satisfied, the amount of change from the number of switch elements detected last time and the amount of change from the voltage value detected last time are acquired, and it is determined that a disconnection has occurred if the amount of change in the number of switch elements does not match the amount of change in the voltage value.

Abstract: A vehicle front lighting apparatus includes a lighting device array in which a plurality of lighting devices are connected in series, a plurality of bypass circuits, a plurality of switch elements, a lighting controller, a current value detector, a voltage value controller, and a disconnection determiner. The voltage value controller applies a voltage to the lighting device array, and controls a voltage value to be applied to cause a value of current flowing through the lighting device array to reach a predetermined target current value. The disconnection determiner determines that there is a disconnection in any of the bypass circuits when the number of the switch elements brought into the opened state does not match the controlled voltage value.

Abstract: A vehicle front lighting apparatus includes a lighting device array in which a plurality of lighting devices are connected in series, a plurality of bypass circuits, a plurality of switch elements, a lighting controller, a current value detector, a voltage value controller, and a disconnection determiner. The voltage value controller applies a voltage to the lighting device array, and controls a voltage value to be applied to cause a value of current flowing through the lighting device array to reach a predetermined target current value. The disconnection determiner determines that there is a disconnection in any of the bypass circuits when the number of the switch elements brought into the opened state does not match the controlled voltage value.

Abstract: In a vehicle front lighting apparatus, the number of switch elements brought into an opened state and an applied voltage value is detected every time a predetermined detection condition is satisfied, the amount of change from the number of switch elements detected last time and the amount of change from the voltage value detected last time are acquired, and it is determined that a disconnection has occurred if the amount of change in the number of switch elements does not match the amount of change in the voltage value.

Abstract: A vehicle front lighting apparatus includes a lighting device array in which multiple lighting devices are connected in series, multiple bypass circuits, multiple switch elements, a lighting intensity detector, a lighting schedule generator, a lighting controller, a current value detector, a voltage value controller, a detector, and a disconnection determiner. When there is the switch element to be brought into a closed state during a prohibition period from a lighting timing to a post-lighting timing, the lighting schedule generator changes a timing at which the switch element is brought into the closed state outside the prohibition period. The disconnection determiner determines that a disconnection has occurred in any of the bypass circuits when the number of switch elements detected at the post-lighting timing does not match a voltage value.

Abstract: The present invention addresses the problem of providing a medicinal composition and a drug combination by which nonalcoholic fatty liver disease and nonalcoholic steatohepatitis can be prevented and/or treated. The present invention provides a combination of a peroxisome proliferator-activated receptor (PPAR) ? agonist with a sodium glucose cotransporter 2 (SGLT2) inhibitor, which is to be used for preventing and/or treating nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.

Abstract: A terminal box includes three or more terminal strips to which output lines of a solar cell module are connected and a box body having an accommodating portion for accommodating the three or more terminal strips. The box body includes inlet holes formed in a face of the box body opposing to the solar cell module and configured for allowing insertion of the output lines corresponding respectively to the three or more terminal strips. The three or more terminal strips include at least two first terminal strips of a same polarity and at least one second terminal strip insulated from the first terminal strips and having the opposite polarity to that of the first terminal strips. The two first terminal strips are electrically connected via a connecting portion disposed on a back face side of the second terminal strip disposed between and aside the two first terminal strips.

Abstract: Provided is a terminal box that allows easy insertion of a tab thereto, irrespectively of the position or direction of the tab extended from a solar cell module. A terminal box with a pair of tabs connected thereto for outputting electric power generated by a solar cell module, includes a case having an accommodating space therein and a pair of electrode plates disposed in the accommodating space. Each one of the pair of electrode plates has a terminal connecting portion to be connected with the tab and a cable connecting portion to which an output cable transmitting the electric power to an external device is connected. The case has tab inserting holes allowing insertion of the tabs into the accommodating space, the tab inserting holes being formed in an opposing face of the case opposing the electrode plates and at positions across the terminal connecting portion of at least one of the pair of electrode plates as the case is viewed perpendicularly above the opposing face.

Abstract: A terminal box that stably and surely provides a required length of play in an output line, and a method of connecting the output line. The terminal box includes a terminal strip connected to the output line, and a main body housing the terminal strip. The terminal strip includes a connecting portion electrically connected to the output line, and a play producing portion. The play producing portion has an opening receiving the output line. The main body includes a receiving hole formed at a position corresponding to the opening for receiving the output line. The play producing portion inclines relative to the connecting portion by a first angle with the output line being inserted through the receiving hole and the opening to be connected to the connecting portion, and by a second angle smaller than the first angle with the output line being connected to the connecting portion.

Abstract: A terminal box includes three or more terminal strips to which output lines of a solar cell module are connected and a box body having an accommodating portion for accommodating the three or more terminal strips. The box body includes inlet holes formed in a face of the box body opposing to the solar cell module and configured for allowing insertion of the output lines corresponding respectively to the three or more terminal strips. The three or more terminal strips include at least two first terminal strips of a same polarity and at least one second terminal strip insulated from the first terminal strips and having the opposite polarity to that of the first terminal strips. The two first terminal strips are electrically connected via a connecting portion disposed on a back face side of the second terminal strip disposed between and aside the two first terminal strips.

Abstract: A light-emitting module may be configured to have improved light emission efficiency and light distribution characteristics. A light-emitting module may include a substrate having a front surface side as a component mounting surface and a rear surface side as a flat heat dissipating surface, a plurality of light-emitting elements arranged in a manner protruding at a central portion of the component mounting surface of the substrate. The light-emitting elements may radiate light at least in an upper surface direction and in a direction along the component mounting surface. The module may further include one or more lighting circuit components electrically connected to the light emitting elements by a wiring pattern arranged on the substrate and which is arranged closer to the peripheral edge side of the substrate than the light emitting elements on the component mounting surface of the substrate, and a connector for power supply connection.

Abstract: A terminal box that can be reliably fixed to a solar cell module is provided. The terminal box includes a bottom wall facing a back surface of the solar cell module, a top wall facing the bottom wall, side walls, and a housing space defined by the bottom wall, the top wall and the side walls to accommodate a component to be mounted. The bottom wall includes a limiting wall formed in a periphery of the bottom wall to project toward the solar cell module, and a communication opening for allowing a charging space defined by the limiting wall and the bottom wall to communicate with the housing space. The limiting wall defines a gap for allowing the charging space to communicate with external space of the limiting wall.

Abstract: A terminal box that stably and surely provides a required length of play in an output line, and a method of connecting the output line. The terminal box includes a terminal strip connected to the output line, and a main body housing the terminal strip. The terminal strip includes a connecting portion electrically connected to the output line, and a play producing portion. The play producing portion has an opening receiving the output line. The main body includes a receiving hole formed at a position corresponding to the opening for receiving the output line. The play producing portion inclines relative to the connecting portion by a first angle with the output line being inserted through the receiving hole and the opening to be connected to the connecting portion, and by a second angle smaller than the first angle with the output line being connected to the connecting portion.

Abstract: Provided is a terminal box that allows easy insertion of a tab thereto, irrespectively of the position or direction of the tab extended from a solar cell module. A terminal box with a pair of tabs connected thereto for outputting electric power generated by a solar cell module, includes a case having an accommodating space therein and a pair of electrode plates disposed in the accommodating space. Each one of the pair of electrode plates has a terminal connecting portion to be connected with the tab and a cable connecting portion to which an output cable transmitting the electric power to an external device is connected. The case has tab inserting holes allowing insertion of the tabs into the accommodating space, the tab inserting holes being formed in an opposing face of the case opposing the electrode plates and at positions across the terminal connecting portion of at least one of the pair of electrode plates as the case is viewed perpendicularly above the opposing face.

Abstract: A light emitting element lamp and a lighting equipment for suppressing a temperature rising of a substrate on which a light emitting element is mounted by using a reflector is described. Aspects relate to a lamp including a heat-conductive reflector, a base connected to the reflector, a heat-conductive heat radiating member, a substrate having a light emitting element mounted thereon and attached to the heat radiating member and a lighting circuit housed in the cover to light the light emitting element. Other components and features may also be included.