Abstract: An illumination device includes a display device, a light-guiding plate, a first coupling member disposed between the display device and the light-guiding plate, a transparent plate, a second coupling member disposed between the light-guiding plate and the transparent plate, and a light source. The light-guiding plate has a first surface in contact with the first coupling member and a second surface in contact with the second coupling member. The first surface is flat. The second surface has a flat part substantially parallel to the display surface and a convex portion that projects from the flat part to the second coupling member side. The convex portion has a first portion inclined to the second coupling member side from upstream to downstream in an emission direction of the light source, and a second portion inclined to the first coupling member side from upstream to downstream in the emission direction.

Abstract: An illumination structure attached to a display surface side of a display structure is provided. The illumination structure includes a light guide plate, a coupling member arranged between the light guide plate and the display surface and coupled to the light guide plate, and a light source arranged so as to illuminate a side surface of the light guide plate. The light guide plate includes a first surface in contact with the coupling member and a second surface opposite to the first surface. The second surface of the light guide plate is flat. The first surface of the light guide plate includes a first portion substantially parallel to the display surface and a second portion recessed from the first portion toward the second surface side.

Abstract: An image display apparatus includes a projection unit configured to project an image and a plurality of concave reflectors in which contact surfaces with optical axes of the concave reflectors with respect to the optical axis of the projection unit are disposed at different angles from one another. A first concave reflector of the plurality of concave reflectors reflects at least a portion of an image projected by the projection unit to form a first image based on the image. A second concave reflector of the plurality of concave reflectors transmits a portion of an image projected by the projection unit and reflects a portion of the image to form a second image based on the image.

Abstract: An image display apparatus includes a projection unit configured to project an image and a plurality of concave reflectors in which contact surfaces with optical axes of the concave reflectors with respect to the optical axis of the projection unit are disposed at different angles from one another. A first concave reflector of the plurality of concave reflectors reflects at least a portion of an image projected by the projection unit to form a first image based on the image. A second concave reflector of the plurality of concave reflectors transmits a portion of an image projected by the projection unit and reflects a portion of the image to form a second image based on the image.

Abstract: Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies.

Abstract: Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies.

Abstract: Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies.

Abstract: Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies.

Abstract: Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies.

Abstract: Methods and compositions for diagnosing and treating Noonan syndrome and neoplastic disorders are provided herein.

Abstract: Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies.

Abstract: In an in-the-ear hearing aid provided with a pull-out type linear member, a housing section is provided to house a pull-out type linear member 25. The housing section is a guide tunnel 24 penetrating a case body 23. The pull-out type linear member 25 is provided, at both ends, with small bulges 25a and 25b. The pull-out type linear member 25 is provided in such a manner that the front small bulge 25b is located outside the guide tunnel 24 and the rear small bulge 25a is located inside the guide tunnel 24. A small diameter port 24a is provided at an opening section of the guide tunnel 24 to serve as a stopper for the rear small bulge 25a.

Abstract: A film formation apparatus that forms a metal film on a substrate is provided. The film formation apparatus includes: a chamber that holds therein the substrate; a material holding section that holds a metal material as a material for the metal film in the chamber; a film formation section that forms the metal film on the substrate by using the metal material; an introduction section that introduces gas into the chamber; and a partial pressure control section that controls the partial pressure of the gas in the chamber to cause the film formation section to form the metal film having a desired density.

Abstract: The invention provides a lift apparatus for use with a ladder having two spaced upright stringers and a plurality of horizontal rungs bridging the stringers and spaced at a distance vertically from one another. The lift apparatus comprises a frame, a prime mover mounted on the frame and having a rotatable output shaft, at least one pair of sprocket systems space apart vertically from each other. At least one of the sprocket systems is operatively coupled with the output shaft of the prime mover. Endless driving force transmitting mechanism can pass around the pair of the sprocket systems. Controller is provided for controlling the prime mover in such a manner as to selectively rotate the output shaft thereof in forward or reverse direction, or stop it. Operating mechanism is provided for causing a plurality of gripper elements to be engaged with the corresponding rungs of the ladder.

Abstract: Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies.

Abstract: An optical coupler having a Y-branch operable to mix and output a first light and a second light from outside. The optical coupler includes: a first input optical wave guide operable to propagate the first light from outside; a second input optical wave guide operable to propagate the second light from outside; an optical coupler operable to output a mixed light, which is a mixture of the first light and the second light; and an output optical wave guide operable to propagate the mixed light and to output it from an end, wherein percentage per unit length of emitting light being propagated in the output optical wave guide to a periphery of the output optical wave guide is higher than that of the first input optical wave guide or the second input optical wave guide.

Abstract: The invention relates to novel ninjurin proteins, nucleic acids, peptides, antibodies and pharmaceutical compositions.

Abstract: The invention provides a lift apparatus for use with a ladder having two spaced upright stringers and a plurality of horizontal rungs bridging the stringers and spaced at a distance vertically from one another. The lift apparatus comprises a frame, a prime mover mounted on the frame and having a rotatable output shaft, at least one pair of sprocket systems space apart vertically from each other. At least one of the sprocket systems is operatively coupled with the output shaft of the prime mover. Endless driving force transmitting means can pass around the pair of the sprocket systems. Controller is provided for controlling the prime mover in such a manner as to selectively rotate the output shaft thereof in forward or reverse direction, or stop it. Operating mechanism is provided for causing a plurality of gripper elements to be engaged with the corresponding rungs of the ladder.

Abstract: A device for supporting development of a system, the device including a first device for registering standard operations of the system into a first library by classifying the standard operations from control and work points of view. The device also includes a second device for registering programs corresponding to a plurality of predetermined system executable functions into a second library by referring to the standard operations registered in the first library.

Abstract: A device for supporting development of a system, the device including first means for registering standard operations of the system into a first library by classifying the standard operations from control and work points of view. The device also includes second means for registering programs corresponding to a plurality of predetermined system executable functions into a second library by referring to the standard operations registered in the first library.