Patents by Inventor Toshiyuki Tsunoda

Toshiyuki Tsunoda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8580562
    Abstract: The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence. The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: November 12, 2013
    Assignee: Fukuoka University
    Inventors: Senji Shirasawa, Takahiro Fujimoto, Toshiyuki Tsunoda, Keiko Doi, Midori Koyanagi
  • Publication number: 20110237647
    Abstract: The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence. The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.
    Type: Application
    Filed: September 8, 2008
    Publication date: September 29, 2011
    Applicant: FUKUOKA UNIVERSITY
    Inventors: Senji Shirasawa, Takahiro Fujimoto, Toshiyuki Tsunoda, Keiko Doi, Midori Koyanagi
  • Patent number: 8004349
    Abstract: High-accuracy overcurrent detection is performed, while a loss resulting from the current detection is significantly reduced. A switch section outputs the voltage between the both terminals of a current detection resistor using an AND signal between an output signal from a hysteresis comparator and an output signal from a pre-driver. The voltage is filtered by an electrostatic capacitor element and a resistor, and inputted to a comparator. The comparator makes a comparison between the signals inputted to the two input terminals thereof, and outputs the result of the comparison to a digital filter. When an overcurrent begins to flow in a power supply unit, the levels of the voltages inputted to the two input terminals of the comparator are inverted so that the comparator outputs an inversion signal to the digital filter. The digital filter outputs a detection signal to an overcurrent detection circuit when an arbitrary time has elapsed.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: August 23, 2011
    Assignee: Renesas Electronics Corporation
    Inventors: Osamu Yamashita, Yasuhiko Kokami, Masahiro Ishihara, Toshiyuki Tsunoda
  • Publication number: 20110063021
    Abstract: High-accuracy overcurrent detection is performed, while a loss resulting from the current detection is significantly reduced. A switch section outputs the voltage between the both terminals of a current detection resistor using an AND signal between an output signal from a hysteresis comparator and an output signal from a pre-driver. The voltage is filtered by an electrostatic capacitor element and a resistor, and inputted to a comparator. The comparator makes a comparison between the signals inputted to the two input terminals thereof, and outputs the result of the comparison to a digital filter. When an overcurrent begins to flow in a power supply unit, the levels of the voltages inputted to the two input terminals of the comparator are inverted so that the comparator outputs an inversion signal to the digital filter. The digital filter outputs a detection signal to an overcurrent detection circuit when an arbitrary time has elapsed.
    Type: Application
    Filed: November 19, 2010
    Publication date: March 17, 2011
    Applicant: RENESAS ELECTRONICS CORPORATION
    Inventors: Osamu YAMASHITA, Yasuhiko KOKAMI, Masahiro ISHIHARA, Toshiyuki TSUNODA
  • Patent number: 7859324
    Abstract: High-accuracy overcurrent detection is performed, while a loss resulting from the current detection is significantly reduced. A switch section outputs the voltage between the both terminals of a current detection resistor using an AND signal between an output signal from a hysteresis comparator and an output signal from a pre-driver. The voltage is filtered by an electrostatic capacitor element and a resistor, and inputted to a comparator. The comparator makes a comparison between the signals inputted to the two input terminals thereof, and outputs the result of the comparison to a digital filter. When an overcurrent begins to flow in a power supply unit, the levels of the voltages inputted to the two input terminals of the comparator are inverted so that the comparator outputs an inversion signal to the digital filter. The digital filter outputs a detection signal to an overcurrent detection circuit when an arbitrary time has elapsed.
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: December 28, 2010
    Assignee: Renesas Electronics Corporation
    Inventors: Osamu Yamashita, Yasuhiko Kokami, Masahiro Ishihara, Toshiyuki Tsunoda
  • Publication number: 20090212851
    Abstract: High-accuracy overcurrent detection is performed, while a loss resulting from the current detection is significantly reduced. A switch section outputs the voltage between the both terminals of a current detection resistor using an AND signal between an output signal from a hysteresis comparator and an output signal from a pre-driver. The voltage is filtered by an electrostatic capacitor element and a resistor, and inputted to a comparator. The comparator makes a comparison between the signals inputted to the two input terminals thereof, and outputs the result of the comparison to a digital filter. When an overcurrent begins to flow in a power supply unit, the levels of the voltages inputted to the two input terminals of the comparator are inverted so that the comparator outputs an inversion signal to the digital filter. The digital filter outputs a detection signal to an overcurrent detection circuit when an arbitrary time has elapsed.
    Type: Application
    Filed: December 23, 2008
    Publication date: August 27, 2009
    Inventors: Osamu YAMASHITA, Yasuhiko Kokami, Masahiro Ishihara, Toshiyuki Tsunoda
  • Publication number: 20050189892
    Abstract: There is provided a drive control system for sensor-less motor wherein a multi-phase sensor-less motor is driven to rotate by switching a current to be applied to a field coil of each phase depending on the rotating phase of motor and such rotating drive is controlled with the PLL control method and the sensor-less motor is driven with higher reliability. When the motor is to be driven, a desired phase is selected as the detection phase and a voltage (Eu, Ev, Ew) induced on the coil of the detection phase is detected when the power is fed for a short period of time to the field coils except for that of the detection phase. A magnetic pole position of a rotor is detected from the amplitude condition of the detected induced voltage and the power feeding phase of the motor drive is determined based on the result of detection of the magnetic pole position.
    Type: Application
    Filed: May 4, 2005
    Publication date: September 1, 2005
    Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
  • Patent number: 6900604
    Abstract: A drive control system, with PLL control, drives a rotatable multi-phase sensor-less motor by switching a current of a field coil of each phase depending on the rotating phase of the motor. When the moto is driven, a desired phase is selected as a datection phase, and a voltage induced on the coil of the detection phase is detected when power is fed for a predetermined time to the field coils other than the detection phase. A magnetic pole position is detected from the amplitude condition of the detected induced voltage. Based on this detection, the power-feeding phase of the motor drive is determined. Power feeding and pole position detection are performed alternately.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: May 31, 2005
    Assignees: Renesas Technology Corp., Hitachi ULSI Systems Co., Ltd., Hitachi Tohbu Semiconductor, Ltd.
    Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
  • Patent number: 6771033
    Abstract: A drive control system, with PLL control, drives a rotatable multi-phase sensor-less motor by switching a current of a field coil of each phase depending on the rotating phase of the motor. When the motor is driven, a desired phase is selected as a detection phase, and a voltage induced on the coil of the detection phase is detected when power is fed for a predetermined time to the field coils other than the detection phase. A magnetic pole position is detected from the amplitude condition of the detected induced voltage. Based on this detection, the power-feeding phase of the motor drive is determined. Power feeding and pole position detection are performed alternately.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: August 3, 2004
    Assignees: Renesas Technology Corp., Hitachi ULSI Systems Co., Ltd., Hitachi Tohbu Semiconductor, Ltd.
    Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
  • Publication number: 20030107338
    Abstract: There is provided a drive control system for sensor-less motor wherein a multi-phase sensor-less motor is driven to rotate by switching a current to be applied to a field coil of each phase depending on the rotating phase of motor and such rotating drive is controlled with the PLL control method and the sensor-less motor is driven with higher reliability. When the motor is to be driven, a desired phase is selected as the detection phase and a voltage (Eu, Ev, Ew) induced on the coil of the detection phase is detected when the power is fed for a short period of time to the field coils except for that of the detection phase. A magnetic pole position of a rotor is detected from the amplitude condition of the detected induced voltage and the power feeding phase of the motor drive is determined based on the result of detection of the magnetic pole position.
    Type: Application
    Filed: January 14, 2003
    Publication date: June 12, 2003
    Applicant: Hitachi, Ltd.
    Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
  • Publication number: 20030107337
    Abstract: There is provided a drive control system for sensor-less motor wherein a multi-phase sensor-less motor is driven to rotate by switching a current to be applied to a field coil of each phase depending on the rotating phase of motor and such rotating drive is controlled with the PLL control method and the sensor-less motor is driven with higher reliability. When the motor is to be driven, a desired phase is selected as the detection phase and a voltage (Eu, Ev, Ew) induced on the coil of the detection phase is detected when the power is fed for a short period of time to the field coils except for that of the detection phase. A magnetic pole position of a rotor is detected from the amplitude condition of the detected induced voltage and the power feeding phase of the motor drive is determined based on the result of detection of the magnetic pole position.
    Type: Application
    Filed: November 12, 2002
    Publication date: June 12, 2003
    Applicant: Hitachi, Ltd.
    Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
  • Patent number: 6563286
    Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.
    Type: Grant
    Filed: December 26, 2001
    Date of Patent: May 13, 2003
    Assignee: Hitachi, Ltd.
    Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
  • Publication number: 20020079860
    Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.
    Type: Application
    Filed: December 26, 2001
    Publication date: June 27, 2002
    Applicant: Hitachi, Ltd.
    Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
  • Patent number: 6344721
    Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: February 5, 2002
    Assignee: Hitachi, Ltd.
    Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
  • Patent number: 6340873
    Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: January 22, 2002
    Assignee: Hitachi, Ltd.
    Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
  • Publication number: 20010050542
    Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.
    Type: Application
    Filed: March 28, 2001
    Publication date: December 13, 2001
    Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
  • Publication number: 20010045812
    Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.
    Type: Application
    Filed: June 29, 2001
    Publication date: November 29, 2001
    Applicant: Hitachi, Ltd.
    Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
  • Patent number: 5621288
    Abstract: A motor speed regulating circuit includes a speed signal generator for generating a speed signal having a frequency proportional to the speed of the motor, synchronously with the rotation of the motor. A time difference detector is used for detecting a time difference between the period of the speed signal and a predetermined standard time. A control voltage generator is used for generating a speed control voltage to be applied to the motor in accordance with a detected time difference and feedback-controlling the speed of the motor in accordance with the standard time. A starter is used for starting the motor after the motor is stopped. The motor can be reliably restarted after it has been stopped.
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: April 15, 1997
    Assignee: Hitachi, Ltd.
    Inventors: Kunio Seki, Toshiyuki Tsunoda, Yuichi Ohkubo
  • Patent number: 5048941
    Abstract: The surgical microscope comprises a stand, an arm movably attached to said stand for sustaining a microscope body, an electric control equipment divided into a plural number of units removably piled up on said stand and a foot switch unit to be used for executing various types of functions. Accommodated in each unit are a function control means having a single specific function or plural specific functions different from those of the other units and an independent power source means connected to said function control means in a relation of 1:1 or in a different combination. The surgical microscope can be designed compact as a whole, has high operability and assures high security during operation. Should a function be lost due to troubles during operation, the surgical microscope prevents the other functions from being influenced by the troubles and allows to speedily restore the lost function.
    Type: Grant
    Filed: October 5, 1989
    Date of Patent: September 17, 1991
    Assignee: Olympus Optical Co., Ltd.
    Inventors: Masami Hamada, Hiroshi Fujiwara, Kosaku Tsuboshima, Masahiko Kinukawa, Toshiyuki Tsunoda, Takashi Nagano, Kazyuki Minami, Shigeo Tokunaga, Masanori Kaneda, Tomonori Ishikawa
  • Patent number: 4878746
    Abstract: A surgical microscope apparatus provided with a failure detecting device for conducting an initial examination and an ordinary examination of an illumination device and a failure detecting device for conducting the ordinary examination of an electric magnification and focusing device, in order to make it possible to self-examine what is defective and indicate the result when failure is caused. The failure of the illumination device is immediately indicated by the self examination of the failure detecting device when a power source is turned on for use.
    Type: Grant
    Filed: April 7, 1988
    Date of Patent: November 7, 1989
    Assignee: Olympus Optical Co., Ltd.
    Inventors: Hiroshi Nakano, Toyoaki Takeuchi, Toshiyuki Tsunoda, Masahiko Kinukawa