Patents by Inventor Toshiyuki Tsunoda
Toshiyuki Tsunoda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8580562Abstract: The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence. The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.Type: GrantFiled: September 8, 2008Date of Patent: November 12, 2013Assignee: Fukuoka UniversityInventors: Senji Shirasawa, Takahiro Fujimoto, Toshiyuki Tsunoda, Keiko Doi, Midori Koyanagi
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Publication number: 20110237647Abstract: The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence. The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.Type: ApplicationFiled: September 8, 2008Publication date: September 29, 2011Applicant: FUKUOKA UNIVERSITYInventors: Senji Shirasawa, Takahiro Fujimoto, Toshiyuki Tsunoda, Keiko Doi, Midori Koyanagi
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Patent number: 8004349Abstract: High-accuracy overcurrent detection is performed, while a loss resulting from the current detection is significantly reduced. A switch section outputs the voltage between the both terminals of a current detection resistor using an AND signal between an output signal from a hysteresis comparator and an output signal from a pre-driver. The voltage is filtered by an electrostatic capacitor element and a resistor, and inputted to a comparator. The comparator makes a comparison between the signals inputted to the two input terminals thereof, and outputs the result of the comparison to a digital filter. When an overcurrent begins to flow in a power supply unit, the levels of the voltages inputted to the two input terminals of the comparator are inverted so that the comparator outputs an inversion signal to the digital filter. The digital filter outputs a detection signal to an overcurrent detection circuit when an arbitrary time has elapsed.Type: GrantFiled: November 19, 2010Date of Patent: August 23, 2011Assignee: Renesas Electronics CorporationInventors: Osamu Yamashita, Yasuhiko Kokami, Masahiro Ishihara, Toshiyuki Tsunoda
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Publication number: 20110063021Abstract: High-accuracy overcurrent detection is performed, while a loss resulting from the current detection is significantly reduced. A switch section outputs the voltage between the both terminals of a current detection resistor using an AND signal between an output signal from a hysteresis comparator and an output signal from a pre-driver. The voltage is filtered by an electrostatic capacitor element and a resistor, and inputted to a comparator. The comparator makes a comparison between the signals inputted to the two input terminals thereof, and outputs the result of the comparison to a digital filter. When an overcurrent begins to flow in a power supply unit, the levels of the voltages inputted to the two input terminals of the comparator are inverted so that the comparator outputs an inversion signal to the digital filter. The digital filter outputs a detection signal to an overcurrent detection circuit when an arbitrary time has elapsed.Type: ApplicationFiled: November 19, 2010Publication date: March 17, 2011Applicant: RENESAS ELECTRONICS CORPORATIONInventors: Osamu YAMASHITA, Yasuhiko KOKAMI, Masahiro ISHIHARA, Toshiyuki TSUNODA
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Patent number: 7859324Abstract: High-accuracy overcurrent detection is performed, while a loss resulting from the current detection is significantly reduced. A switch section outputs the voltage between the both terminals of a current detection resistor using an AND signal between an output signal from a hysteresis comparator and an output signal from a pre-driver. The voltage is filtered by an electrostatic capacitor element and a resistor, and inputted to a comparator. The comparator makes a comparison between the signals inputted to the two input terminals thereof, and outputs the result of the comparison to a digital filter. When an overcurrent begins to flow in a power supply unit, the levels of the voltages inputted to the two input terminals of the comparator are inverted so that the comparator outputs an inversion signal to the digital filter. The digital filter outputs a detection signal to an overcurrent detection circuit when an arbitrary time has elapsed.Type: GrantFiled: December 23, 2008Date of Patent: December 28, 2010Assignee: Renesas Electronics CorporationInventors: Osamu Yamashita, Yasuhiko Kokami, Masahiro Ishihara, Toshiyuki Tsunoda
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Publication number: 20090212851Abstract: High-accuracy overcurrent detection is performed, while a loss resulting from the current detection is significantly reduced. A switch section outputs the voltage between the both terminals of a current detection resistor using an AND signal between an output signal from a hysteresis comparator and an output signal from a pre-driver. The voltage is filtered by an electrostatic capacitor element and a resistor, and inputted to a comparator. The comparator makes a comparison between the signals inputted to the two input terminals thereof, and outputs the result of the comparison to a digital filter. When an overcurrent begins to flow in a power supply unit, the levels of the voltages inputted to the two input terminals of the comparator are inverted so that the comparator outputs an inversion signal to the digital filter. The digital filter outputs a detection signal to an overcurrent detection circuit when an arbitrary time has elapsed.Type: ApplicationFiled: December 23, 2008Publication date: August 27, 2009Inventors: Osamu YAMASHITA, Yasuhiko Kokami, Masahiro Ishihara, Toshiyuki Tsunoda
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Publication number: 20050189892Abstract: There is provided a drive control system for sensor-less motor wherein a multi-phase sensor-less motor is driven to rotate by switching a current to be applied to a field coil of each phase depending on the rotating phase of motor and such rotating drive is controlled with the PLL control method and the sensor-less motor is driven with higher reliability. When the motor is to be driven, a desired phase is selected as the detection phase and a voltage (Eu, Ev, Ew) induced on the coil of the detection phase is detected when the power is fed for a short period of time to the field coils except for that of the detection phase. A magnetic pole position of a rotor is detected from the amplitude condition of the detected induced voltage and the power feeding phase of the motor drive is determined based on the result of detection of the magnetic pole position.Type: ApplicationFiled: May 4, 2005Publication date: September 1, 2005Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
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Patent number: 6900604Abstract: A drive control system, with PLL control, drives a rotatable multi-phase sensor-less motor by switching a current of a field coil of each phase depending on the rotating phase of the motor. When the moto is driven, a desired phase is selected as a datection phase, and a voltage induced on the coil of the detection phase is detected when power is fed for a predetermined time to the field coils other than the detection phase. A magnetic pole position is detected from the amplitude condition of the detected induced voltage. Based on this detection, the power-feeding phase of the motor drive is determined. Power feeding and pole position detection are performed alternately.Type: GrantFiled: November 12, 2002Date of Patent: May 31, 2005Assignees: Renesas Technology Corp., Hitachi ULSI Systems Co., Ltd., Hitachi Tohbu Semiconductor, Ltd.Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
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Patent number: 6771033Abstract: A drive control system, with PLL control, drives a rotatable multi-phase sensor-less motor by switching a current of a field coil of each phase depending on the rotating phase of the motor. When the motor is driven, a desired phase is selected as a detection phase, and a voltage induced on the coil of the detection phase is detected when power is fed for a predetermined time to the field coils other than the detection phase. A magnetic pole position is detected from the amplitude condition of the detected induced voltage. Based on this detection, the power-feeding phase of the motor drive is determined. Power feeding and pole position detection are performed alternately.Type: GrantFiled: January 14, 2003Date of Patent: August 3, 2004Assignees: Renesas Technology Corp., Hitachi ULSI Systems Co., Ltd., Hitachi Tohbu Semiconductor, Ltd.Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
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Publication number: 20030107338Abstract: There is provided a drive control system for sensor-less motor wherein a multi-phase sensor-less motor is driven to rotate by switching a current to be applied to a field coil of each phase depending on the rotating phase of motor and such rotating drive is controlled with the PLL control method and the sensor-less motor is driven with higher reliability. When the motor is to be driven, a desired phase is selected as the detection phase and a voltage (Eu, Ev, Ew) induced on the coil of the detection phase is detected when the power is fed for a short period of time to the field coils except for that of the detection phase. A magnetic pole position of a rotor is detected from the amplitude condition of the detected induced voltage and the power feeding phase of the motor drive is determined based on the result of detection of the magnetic pole position.Type: ApplicationFiled: January 14, 2003Publication date: June 12, 2003Applicant: Hitachi, Ltd.Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
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Publication number: 20030107337Abstract: There is provided a drive control system for sensor-less motor wherein a multi-phase sensor-less motor is driven to rotate by switching a current to be applied to a field coil of each phase depending on the rotating phase of motor and such rotating drive is controlled with the PLL control method and the sensor-less motor is driven with higher reliability. When the motor is to be driven, a desired phase is selected as the detection phase and a voltage (Eu, Ev, Ew) induced on the coil of the detection phase is detected when the power is fed for a short period of time to the field coils except for that of the detection phase. A magnetic pole position of a rotor is detected from the amplitude condition of the detected induced voltage and the power feeding phase of the motor drive is determined based on the result of detection of the magnetic pole position.Type: ApplicationFiled: November 12, 2002Publication date: June 12, 2003Applicant: Hitachi, Ltd.Inventors: Yasuhiko Kokami, Kunihiro Kawauchi, Toshiyuki Tsunoda, Reiichi Kimura
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Patent number: 6563286Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.Type: GrantFiled: December 26, 2001Date of Patent: May 13, 2003Assignee: Hitachi, Ltd.Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
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Publication number: 20020079860Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.Type: ApplicationFiled: December 26, 2001Publication date: June 27, 2002Applicant: Hitachi, Ltd.Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
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Patent number: 6344721Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.Type: GrantFiled: March 28, 2001Date of Patent: February 5, 2002Assignee: Hitachi, Ltd.Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
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Patent number: 6340873Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.Type: GrantFiled: June 29, 2001Date of Patent: January 22, 2002Assignee: Hitachi, Ltd.Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
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Publication number: 20010050542Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.Type: ApplicationFiled: March 28, 2001Publication date: December 13, 2001Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
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Publication number: 20010045812Abstract: A pulse current having such a short duration as the rotor does not react is passed through field coils of respective phases of a brushless motor in first and second, mutually opposite, directions sequentially, voltages induced, by the pulse currents in two directions at each of the field coils of the non-conducting phase are combined, the polarity of a combined voltage is detected, and a field coil pair where a current is to be passed to start the motor is determined based on the result of detection for each of field coil of the non-conducting phase.Type: ApplicationFiled: June 29, 2001Publication date: November 29, 2001Applicant: Hitachi, Ltd.Inventors: Kunio Seki, Toshiyuki Tsunoda, Yasuhiko Kokami, Kunihiro Kawauchi
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Patent number: 5621288Abstract: A motor speed regulating circuit includes a speed signal generator for generating a speed signal having a frequency proportional to the speed of the motor, synchronously with the rotation of the motor. A time difference detector is used for detecting a time difference between the period of the speed signal and a predetermined standard time. A control voltage generator is used for generating a speed control voltage to be applied to the motor in accordance with a detected time difference and feedback-controlling the speed of the motor in accordance with the standard time. A starter is used for starting the motor after the motor is stopped. The motor can be reliably restarted after it has been stopped.Type: GrantFiled: November 14, 1994Date of Patent: April 15, 1997Assignee: Hitachi, Ltd.Inventors: Kunio Seki, Toshiyuki Tsunoda, Yuichi Ohkubo
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Patent number: 5048941Abstract: The surgical microscope comprises a stand, an arm movably attached to said stand for sustaining a microscope body, an electric control equipment divided into a plural number of units removably piled up on said stand and a foot switch unit to be used for executing various types of functions. Accommodated in each unit are a function control means having a single specific function or plural specific functions different from those of the other units and an independent power source means connected to said function control means in a relation of 1:1 or in a different combination. The surgical microscope can be designed compact as a whole, has high operability and assures high security during operation. Should a function be lost due to troubles during operation, the surgical microscope prevents the other functions from being influenced by the troubles and allows to speedily restore the lost function.Type: GrantFiled: October 5, 1989Date of Patent: September 17, 1991Assignee: Olympus Optical Co., Ltd.Inventors: Masami Hamada, Hiroshi Fujiwara, Kosaku Tsuboshima, Masahiko Kinukawa, Toshiyuki Tsunoda, Takashi Nagano, Kazyuki Minami, Shigeo Tokunaga, Masanori Kaneda, Tomonori Ishikawa
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Patent number: 4878746Abstract: A surgical microscope apparatus provided with a failure detecting device for conducting an initial examination and an ordinary examination of an illumination device and a failure detecting device for conducting the ordinary examination of an electric magnification and focusing device, in order to make it possible to self-examine what is defective and indicate the result when failure is caused. The failure of the illumination device is immediately indicated by the self examination of the failure detecting device when a power source is turned on for use.Type: GrantFiled: April 7, 1988Date of Patent: November 7, 1989Assignee: Olympus Optical Co., Ltd.Inventors: Hiroshi Nakano, Toyoaki Takeuchi, Toshiyuki Tsunoda, Masahiko Kinukawa