Patents by Inventor Trevor Alan Hatton

Trevor Alan Hatton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8772197
    Abstract: One aspect of the present invention relates to reactive compositions and methods of use thereof, wherein a metal oxide cluster is used to connect a reactive group (or groups) to the surface of a substrate. In certain embodiments, the reactive group in the compositions decomposes organophosphate agents through nucleophilic hydrolysis. In certain embodiments, the reactive group in the compositions is bactericidal. Remarkably, the use of metal oxide clusters in the disclosed compositions and methods permits incorporation of higher quantities of nucleophilic and bactericidal groups without the difficulties associated with having to pretreat the substrate prior to its association with the reactive groups.
    Type: Grant
    Filed: August 18, 2008
    Date of Patent: July 8, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Trevor Alan Hatton, Lev E. Bromberg, Huan Zhang
  • Patent number: 8684189
    Abstract: Described is the application of layer-by-layer (LbL) electrostatic assembly techniques to electrospun nanofibers in order to fabricate novel, breathable electrospun fiber-based chemical and biological detoxifying protective fabrics and filters. The combination of layer-by-layer electrostatic assembly and electrospinning technique allows one to take advantage of high specific surface area, light weight and breathability of electrospun fiber mats while simultaneously providing the versatility to incorporate different functional polyelectrolytes to achieve multifunctional coatings for both chemical and biological protection together. The functionalized fiber mats can be incorporated into breathable chemical and biological protective fabrics, filters and masks. In addition, LbL electrostatic coating of porous non-woven materials provides the versatility to generate multifunctional polymer-based membrane materials for other applications.
    Type: Grant
    Filed: July 21, 2010
    Date of Patent: April 1, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Liang Chen, Lev E. Bromberg, Trevor Alan Hatton, Gregory C. Rutledge
  • Publication number: 20130310575
    Abstract: Described herein are inventive methods for synthesis of cyclic carbonates from CO2 and epoxide. In some embodiments, the methods are carried out in the presence of a catalyst comprising an electrophilic halogen. In some embodiments, the methods are carried out in a flow reactor.
    Type: Application
    Filed: March 14, 2013
    Publication date: November 21, 2013
    Inventors: Trevor Alan Hatton, Timothy F. Jamison, Jennifer Aiden Kozak, Fritz Simeon, Jie Wu
  • Patent number: 8436116
    Abstract: One aspect of the present invention relates to polymers containing redox-responsive moieties (such as, ferrocene). In certain embodiments, the present invention relates to in-situ continuous separation systems which use such redox-responsive polymers for low-molecular weight alcohol removal from an aqueous mixture; such systems enhance the production of low-molecular weight alcohols by reducing the product inhibition effects that plague their production from bio-mass by fermentation.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: May 7, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Abhinav Akhoury, Lev E. Bromberg, Trevor Alan Hatton
  • Publication number: 20130058857
    Abstract: The present invention generally relates to methods and systems for carrying out a pH-influenced chemical and/or biological reaction. In some embodiments, the pH-influenced reaction involves the conversion of CO2 to a dissolved species.
    Type: Application
    Filed: August 29, 2012
    Publication date: March 7, 2013
    Applicant: Massachusetts Institute of Technology
    Inventors: Michael C. Stern, Fritz Simeon, Trevor Alan Hatton
  • Publication number: 20130032160
    Abstract: Described herein are compositions and methods for capturing carbonylic or phenolic toxicants, or converting these toxicants into less volatile compounds. The toxicants, which may be a component of cigarette smoke, may be captured by physical or chemical adsorption, absorption, or entrapment.
    Type: Application
    Filed: August 1, 2011
    Publication date: February 7, 2013
    Inventors: Lev E. Bromberg, Trevor Alan Hatton
  • Publication number: 20120305174
    Abstract: Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet.
    Type: Application
    Filed: April 27, 2012
    Publication date: December 6, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Bernhardt Levy Trout, Trevor Alan Hatton, Emily Chang, James MB Evans, Salvatore Mascia, Won Kim, Ryan Richard Slaughter, Yi Du, Himanshu Hemant Dhamankar, Keith M. Forward, Gregory C. Rutledge, Mao Wang, Allan Stuart Myerson, Blair Kathryn Brettmann, Nikhil Padhye, Jung-Hoon Chun
  • Publication number: 20120135080
    Abstract: The invention provides core-shell magnetic particles comprising a magnetic core and a functional shell, methods for making same, methods of separation using same, methods for using same, and devices comprising same. The particles and methods of the invention are useful for targeting and removing substances of interest that may be found in complex mixtures.
    Type: Application
    Filed: November 4, 2011
    Publication date: May 31, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Lev E. Bromberg, Emily P. Chang, Trevor Alan Hatton
  • Publication number: 20120076860
    Abstract: The present invention generally relates to compositions, methods, and systems relating to controlled crystallization and/or nucleation of a molecular species. In some embodiments, the crystallization and/or nucleation of the molecular species may be controlled by tuning the surface chemistry and/or the morphology of a crystallization substrate. In some embodiments, the molecular species is a small organic molecule (e.g., pharmaceutically active agent).
    Type: Application
    Filed: August 23, 2011
    Publication date: March 29, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: Bernhardt Levy Trout, Patrick S. Doyle, Trevor Alan Hatton, Allan Stuart Myerson, Ying Diao, Matthew E. Helgeson
  • Publication number: 20110027869
    Abstract: One aspect of the present invention relates to reactive compositions and methods of use thereof, wherein a metal oxide cluster is used to connect a reactive group (or groups) to the surface of a substrate. In certain embodiments, the reactive group in the compositions decomposes organophosphate agents through nucleophilic hydrolysis. In certain embodiments, the reactive group in the compositions is bactericidal. Remarkably, the use of metal oxide clusters in the disclosed compositions and methods permits incorporation of higher quantities of nucleophilic and bactericidal groups without the difficulties associated with having to pretreat the substrate prior to its association with the reactive groups.
    Type: Application
    Filed: August 18, 2008
    Publication date: February 3, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Trevor Alan Hatton, Lev E. Bromberg, Huan Zhang
  • Publication number: 20100285081
    Abstract: One aspect of the invention relates to an antimicrobial fiber formed from an electroprocessed blend of at least one polymer, at least one antimicrobial agent, and at least one crosslinker. Another aspect of the invention relates to an antimicrobial fiber formed from an electroprocessed blend of at least one polymer and at least one crosslinker, which is then coated with an antimicrobial compound or antimicrobial polymer.
    Type: Application
    Filed: November 12, 2008
    Publication date: November 11, 2010
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Liang Chen, Lev E. Bromberg, Trevor Alan Hatton, Gregory C. Rutledge
  • Publication number: 20100222519
    Abstract: One aspect of the present invention relates to polymers containing redox-responsive moieties (such as, ferrocene). In certain embodiments, the present invention relates to in-situ continuous separation systems which use such redox-responsive polymers for low-molecular weight alcohol removal from an aqueous mixture; such systems enhance the production of low-molecular weight alcohols by reducing the product inhibition effects that plague their production from bio-mass by fermentation.
    Type: Application
    Filed: February 27, 2009
    Publication date: September 2, 2010
    Applicant: Massachusetts Institute of Technology
    Inventors: Abhinav Akhoury, Lev E. Bromberg, Trevor Alan Hatton