Patents by Inventor Tsun P. Au Yeung

Tsun P. Au Yeung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED THERAPEUTICS
    Publication number: 20220395498
    Abstract: The present invention provides pharmacological compounds including an effector moiety conjugated to a binding moiety that directs the effector moiety to a biological target of interest. Likewise, the present invention provides compositions, kits, and methods (e.g., therapeutic, diagnostic, and imaging) including the compounds. The compounds can be described as a protein interacting binding moiety-drug conjugate (SDC-TRAP) compounds, which include a protein interacting binding moiety and an effector moiety. For example, in certain embodiments directed to treating cancer, the SDC-TRAP can include an Hsp90 inhibitor conjugated to a cytotoxic agent as the effector moiety.
    Type: Application
    Filed: July 29, 2022
    Publication date: December 15, 2022
    Inventors: Leila Alland, Christopher Sears, Rajesh R. Shinde, Beata Sweryda-Krawiec, Tsun P. Au Yeung, Mark T. Bilodeau, Sudhakar Kadiyala, Eugene Zhorov, Richard Wooster
  • TARGETED THERAPEUTICS
    Publication number: 20200230126
    Abstract: The present invention provides pharmacological compounds including an effector moiety conjugated to a binding moiety that directs the effector moiety to a biological target of interest. Likewise, the present invention provides compositions, kits, and methods (e.g., therapeutic, diagnostic, and imaging) including the compounds. The compounds can be described as a protein interacting binding moiety-drug conjugate (SDC-TRAP) compounds, which include a protein interacting binding moiety and an effector moiety. For example, in certain embodiments directed to treating cancer, the SDC-TRAP can include an Hsp90 inhibitor conjugated to a cytotoxic agent as the effector moiety.
    Type: Application
    Filed: June 19, 2018
    Publication date: July 23, 2020
    Inventors: Leila Alland, Christopher Sears, Rajesh R. Shinde, Beata Sweryda-Krawiec, Tsun P. Au Yeung, Mark T. Bilodeau, Sudhakar Kadiyala, Eugene Zhorov, Richard Wooster
  • PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20190350940
    Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein.
    Type: Application
    Filed: May 16, 2019
    Publication date: November 21, 2019
    Inventors: Rossitza G. Alargova, Mark T. Bilodeau, Richard Wooster, Benoît Moreau, Kerry Whalen, J. Michael Ramstack, Danielle N. Rockwood, Patrick Lim Soo, Sukhjeet Singh, Tsun P. Au Yeung, Charles-Andre Lemelin, Linda M. Custer
  • Platinum compounds, compositions, and uses thereof
    Patent number: 10342801
    Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: July 9, 2019
    Assignee: PLACON THERAPEUTICS, INC.
    Inventors: Rossitza G. Alargova, Mark T. Bilodeau, Richard Wooster, Benoît Moreau, Kerry Whalen, J. Michael Ramstack, Danielle N. Rockwood, Patrick Lim Soo, Sukhjeet Singh, Tsun P. Au Yeung, Charles-Andre Lemelin, Linda M. Custer
  • PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20180243318
    Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein.
    Type: Application
    Filed: June 22, 2016
    Publication date: August 30, 2018
    Inventors: Rossitza G. Alargova, Mark T. Bilodeau, Richard Wooster, Benoît Moreau, Kerry Whalen, J. Michael Ramstack, Danielle N. Rockwood, Patrick Lim Soo, Sukhjeet Singh, Tsun P. Au Yeung, Charles-Andre Lemelin, Linda M. Custer