Patents by Inventor Tu Ngoc Nguyen

Tu Ngoc Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective near-infrared optical imaging of necrotic cells and simultaneous cell fixing and counter staining with metallacrown complexes
    Patent number: 11408893
    Abstract: A method for selective labelling of necrotic cells including incubating the cells in a solution including a Ln(III)Zn16(HA ligand)16 metallacrown complex, wherein the HA ligand is a hydroximate ligand.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: August 9, 2022
    Assignees: The Regents of the University of Michigan, Centre National De La Recherche Scientifique
    Inventors: Ivana Martinic, Tu Ngoc Nguyen, Svetlana V. Eliseeva, Vincent L. Pecoraro, Stéphane Petoud
  • SELECTIVE NEAR-INFRARED OPTICAL IMAGING OF NECROTIC CELLS AND SIMULTANEOUS CELL FIXING AND COUNTER STAINING WITH METALLACROWN COMPLEXES
    Publication number: 20200064350
    Abstract: A method for selective labelling of necrotic cells including incubating the cells in a solution including a Ln(III)Zn16(HA ligand)16 metallacrown complex, wherein the HA ligand is a hydroximate ligand.
    Type: Application
    Filed: August 21, 2019
    Publication date: February 27, 2020
    Inventors: Ivana MARTINIC, Tu Ngoc NGUYEN, Svetlana V. ELISEEVA, Vincent L. PECORARO, Stéphane PETOUD
  • Ln(III) and Ga(III) metallacrown complexes
    Patent number: 10562920
    Abstract: The present invention concerns heterometallic metallacrown compounds incorporating Ga(III) and Ln(III) cations, with a templating ligand such as salicylhydroxamic acid or derivatives thereof, wherein said metallacrown contains at least one repeating [—Ga—N—O—] sub-unit where the N—O derives from the templating ligand.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: February 18, 2020
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Evan R. Trivedi, Vincent L. Pecoraro, Svetlana V. Eliseeva, Stépane Petoud, Chun Y. Chow, Tu Ngoc Nguyen, Jacob Charles Lutter, Ivana Martinic
  • Selective near-infrared optical imaging of necrotic cells and simultaneous cell fixing and counter staining with metallacrown complexes
    Patent number: 10458991
    Abstract: In an example of a method for simultaneously fixing and staining cells, the cells are initially incubated in a solution including a Ln(III)Zn16(HA ligand)16 metallacrown complex, wherein the HA ligand is a hydroximate ligand. The incubating cells are exposed to ultraviolet (UV) light. The cells are allowed to continue to incubate in the solution after UV light exposure.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: October 29, 2019
    Assignees: The Regents of the University of Michigan, Centre National de la Recherche Scientifique
    Inventors: Ivana Martinic, Tu Ngoc Nguyen, Svetlana V. Eliseeva, Vincent L. Pecoraro, Stéphane Petoud
  • Selective near-infrared optical imaging of necrotic cells and simultaneous cell fixing and counter staining with metallacrown complexes
    Patent number: 10359430
    Abstract: In an example of a method for simultaneously fixing and staining cells, the cells are initially incubated in a solution including a Ln(III)Zn16(HA ligand)16 metallacrown complex, wherein the HA ligand is a hydroximate ligand. The incubating cells are exposed to ultraviolet (UV) light. The cells are allowed to continue to incubate in the solution after UV light exposure.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: July 23, 2019
    Assignees: The Regents of the University of Michigan, Centre National de la Recherche Scientifique
    Inventors: Ivana Martinic, Tu Ngoc Nguyen, Svetlana V. Eliseeva, Vincent L. Pecoraro, Stéphane Petoud
  • SELECTIVE NEAR-INFRARED OPTICAL IMAGING OF NECROTIC CELLS AND SIMULTANEOUS CELL FIXING AND COUNTER STAINING WITH METALLACROWN COMPLEXES
    Publication number: 20180238897
    Abstract: In an example of a method for simultaneously fixing and staining cells, the cells are initially incubated in a solution including a Ln(III)Zn16(HA ligand)16 metallacrown complex, wherein the HA ligand is a hydroximate ligand. The incubating cells are exposed to ultraviolet (UV) light. The cells are allowed to continue to incubate in the solution after UV light exposure.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 23, 2018
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Ivana MARTINIC, Tu Ngoc NGUYEN, Svetlana V. ELISEEVA, Vincent L. PECORARO, Stéphane PETOUD
  • LN(III) AND GA(III) METALLACROWN COMPLEXES
    Publication number: 20180127438
    Abstract: The present invention concerns heterometallic metallacrown compounds incorporating Ga(III) and Ln(III) cations, with a templating ligand such as salicylhydroxamic acid or derivatives thereof, wherein said metallacrown contains at least one repeating [—Ga—N—O—] sub-unit where the N—O derives from the templating ligand.
    Type: Application
    Filed: April 18, 2016
    Publication date: May 10, 2018
    Inventors: Evan R. Trivedi, Vincent L. Pecoraro, Svetlana V. Eliseeva, Stépane Petoud, Chun Y, Chow, Tu Ngoc Nguyen, Jacob Charles Lutter, Ivana Martinic