Patents by Inventor Tyco M. Scholtens

Tyco M. Scholtens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imaging of immunomagnetically enriched rare cells
    Patent number: 8569077
    Abstract: A method for removing excess unbound ferrofluid and imaging immunomagnetically enriched circulating tumor cells is provided. A vessels having a preformed grooves in the viewing surface is optimally designed for cell alignment and imaging. After separating the unbound particles by centrifugation, an externally-applied force is applied to transport magnetically responsive particle-CTC complex toward the transparent collection wall. The grooved inner surface of the viewing face of the chamber provide uniform distribution of the particles for easy imaging. The invention is also useful in conducting quantitative analysis and sample preparation in conjunction with automated cell enumeration techniques as in quantitative analysis of CTC in disease.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: October 29, 2013
    Assignee: Veridex, LLC
    Inventors: Tyco M. Scholtens, Frederik Schreuder, Jan Greve, Arjan G. J. Tibbe, Leon W. M. M. Terstappen
  • IMAGING OF IMMUNOMAGNETICALLY ENRICHED RARE CELLS
    Publication number: 20090286264
    Abstract: A method for removing excess unbound ferrofluid and imaging immunomagnetically enriched circulating tumor cells is provided. A vessels having a preformed grooves in the viewing surface is optimally designed for cell alignment and imaging. After separating the unbound particles by centrifugation, an externally-applied force is applied to transport magnetically responsive particle-CTC complex toward the transparent collection wall. The grooved inner surface of the viewing face of the chamber provide uniform distribution of the particles for easy imaging. The invention is also useful in conducting quantitative analysis and sample preparation in conjunction with automated cell enumeration techniques as in quantitative analysis of CTC in disease.
    Type: Application
    Filed: May 18, 2009
    Publication date: November 19, 2009
    Inventors: Tyco M. Scholtens, Frederik Schreuder, Jan Greve, Arhjan G.J. Tibbe, Leon W.M.M. Terstappen