Patents by Inventor Tyrrell Errick Norris

Tyrrell Errick Norris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human Ste20-like stress activated serine/threonine kinase
    Publication number: 20020132296
    Abstract: A novel human signal-transduction kinase polypeptide is described which is expressed at a particularly high level in human leukocytes. A full length cDNA which encodes the novel stress-activated serine/threonine kinase polypeptide is disclosed as well as the interior structural region and the amino acid residue sequence of the native biological molecule. Methods are provided to identify compounds that modulate the biological activity of the human Ste20-like stress-activated serine/threonine signal transduction kinase.
    Type: Application
    Filed: July 16, 2001
    Publication date: September 19, 2002
    Inventors: William Craig Moore, Tyrrell Errick Norris, David Shay Silberstein
  • Human signal transduction serine/threonine kinase
    Patent number: 6300098
    Abstract: An isolated and purified human Ste20-like serine/threonine signal transduction kinase is described. A cDNA sequence which encodes the native signal transduction molecule is disclosed as well as the structural coding region and the amino acid residue sequence. Methods are provided which employ the sequences to identify compounds that modulate the biological and/or pharmacological activity of the transduction molecule and hence regulate cell physiology. Biologically-effective antisense molecules, as well as dominant negative mutant versions of the biomolecule are described which are suitable for therapeutic use. The invention is also drawn toward the diagnosis, prevention, and treatment of pathophysiological disorders mediated by the signal transduction molecule.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: October 9, 2001
    Assignee: Zeneca Limited
    Inventors: Tyrrell Errick Norris, William Craig Moore, David Shay Silberstein
  • Human Ste20-like stress activated serine/threonine kinase
    Patent number: 6265560
    Abstract: A novel human signal-transduction kinase polypeptide is described which is expressed at a particularly high level in human leukocytes. A full length cDNA which encodes the novel stress-activated serine/threonine kinase polypeptide is disclosed as well as the interior structural region and the amino acid residue sequence of the native biological molecule. Methods are provided to identify compounds that modulate the biological activity of the human Ste20-like stress-activated serine/threonine signal transduction kinase.
    Type: Grant
    Filed: September 14, 1998
    Date of Patent: July 24, 2001
    Assignee: Zeneca Ltd.
    Inventors: William Craig Moore, Tyrrell Errick Norris, David Shay Silberstein
  • Human signal transduction serine/threonine kinase
    Patent number: 6034228
    Abstract: An isolated and purified human Ste20-like serine/threonine signal transduction kinase is described. A cDNA sequence which encodes the native signal transduction molecule is disclosed as well as the structural coding region and the amino acid residue sequence. Methods are provided which employ the sequences to identify compounds that modulate the biological and/or pharmacological activity of the transduction molecule and hence regulate cell physiology. Biologically-effective antisense molecules, as well as dominant negative mutant versions of the biomolecule are described which are suitable for therapeutic use. The invention is also drawn toward the diagnosis, prevention, and treatment of pathophysiological disorders mediated by the signal transduction molecule.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: March 7, 2000
    Assignee: Zeneca Limited
    Inventors: Tyrrell Errick Norris, William Craig Moore, David Shay Silberstein
  • Human signal transduction serine/threonine kinase
    Patent number: 5962265
    Abstract: A novel human signal-transduction kinase polypeptide is described which is expressed at a particularly high level in tissues of the human immune system. A full length cDNA which encodes the novel signal transduction serine/threonine kinase polypeptide is disclosed as well as the interior structural region and the amino acid residue sequence of the native biological molecule. Methods are provided to identify compounds that modulate the biological activity of the human Ste20-like serine/threonine signal transduction kinase.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: October 5, 1999
    Assignee: Zeneca Limited
    Inventors: Tyrrell Errick Norris, William Craig Moore, David Shay Silberstein