Patents by Inventor Ulrich Hans Thomann
Ulrich Hans Thomann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240026415Abstract: The invention features methods, panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.Type: ApplicationFiled: October 25, 2022Publication date: January 25, 2024Inventors: Ulrich Hans THOMANN, Lori Anne NEELY, Heidi Susanne GIESE, Jessica Ann TOWNSEND, Rahul Krishan DHANDA, Thomas Jay LOWERY, JR., Urvi VED, Brendan MANNING, Nu Ai PHUNG, Joanne Lawton GARVER, Benjamin B. STONE
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Patent number: 11519016Abstract: The invention features methods panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.Type: GrantFiled: January 20, 2017Date of Patent: December 6, 2022Assignee: T2 Biosystems, Inc.Inventors: Ulrich Hans Thomann, Lori Anne Neely, Heidi Susanne Giese, Jessica Ann Townsend, Rahul Krishan Dhanda, Thomas Jay Lowery, Jr., Urvi Ved, Brendan Manning, Nu Ai Phung, Joanne Lawton Garver, Benjamin B. Stone
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Publication number: 20220228199Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.Type: ApplicationFiled: April 5, 2022Publication date: July 21, 2022Inventors: Ulrich Hans THOMANN, Lori Anne NEELY, Rahul Krishan DHANDA, Frédéric SWEENEY, Thomas Jay LOWERY, JR., Jessica Ann TOWNSEND, Jessica Lee SNYDER, Heidi Susanne GIESE, Cheryl Ann BANDOSKI-GRALINSKI, Daniella Lynn LOGAN
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Patent number: 11326213Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.Type: GrantFiled: January 21, 2016Date of Patent: May 10, 2022Assignee: T2 Biosystems, Inc.Inventors: Ulrich Hans Thomann, Lori Anne Neely, Rahul Krishan Dhanda, Frédéric Sweeney, Thomas Jay Lowery, Jr., Jessica Ann Townsend, Jessica Lee Snyder, Heidi Susanne Giese, Cheryl Ann Bandoski-Gralinski, Daniella Lynn Logan
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Patent number: 11110461Abstract: The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics.Type: GrantFiled: February 12, 2018Date of Patent: September 7, 2021Assignee: ANDE CORPORATIONInventors: Eugene Tan, Heung Chuan Lam, Valery Leonidovich Bogdanov, Gregory John Kellogg, John A. Wright, Ulrich Hans Thomann, Richard F. Selden
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Publication number: 20210002715Abstract: The invention features methods, systems, and cartridges for amplification of target nucleic acids in complex samples, for example, whole blood. The invention also features diagnostic and therapeutic methods based on amplification of target nucleic acids characteristic of pathogens present in complex samples containing cells and/or cell debris, for example, whole blood.Type: ApplicationFiled: April 12, 2017Publication date: January 7, 2021Inventors: Ulrich Hans THOMANN, Jessica Lee SNYDER, Thomas Jay LOWERY, Jr.
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Publication number: 20190071707Abstract: The invention features methods panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.Type: ApplicationFiled: January 20, 2017Publication date: March 7, 2019Inventors: Ulrich Hans THOMANN, Lori Anne NEELY, Heidi Susanne GIESE, Jessica Ann TOWNSEND, Rahul Krishan DHANDA, Thomas Jay LOWERY, Jr., Urvi VED, Brendan MANNING, Nu Ai PHUNG, Joanne Lawton GARVER, Benjamin B. STONE
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Publication number: 20190032104Abstract: The invention features methods, panels, cartridges, kits, and systems for rapid and sensitive detection and identification of pathogens and determination of the pathogen's susceptibility to antimicrobial agents for diagnosis and treatment of disease, including bloodstream infection (e.g., bacteremia and fungemia), and sepsis.Type: ApplicationFiled: January 20, 2017Publication date: January 31, 2019Applicant: T2 Biosystems, Inc.Inventors: Thomas Jay LOWERY, JR., Michael Andy PFALLER, Rahul Krishan DHANDA, John J. MCDONOUGH, Glenn MAGNUSON, Lori Anne NEELY, Ulrich Hans THOMANN, William Coulter HARRIS, Justin Layne BLACK
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Publication number: 20180169660Abstract: The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics.Type: ApplicationFiled: February 12, 2018Publication date: June 21, 2018Inventors: Eugene Tan, Heung Chuan Lam, Valery Leonidovich Bogdanov, Gregory John Kellogg, John A. Wright, Ulrich Hans Thomann, Richard F. Selden
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Publication number: 20180171388Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.Type: ApplicationFiled: January 21, 2016Publication date: June 21, 2018Inventors: Ulrich Hans THOMANN, Lori Anne NEELY, Rahul Krishan DHANDA, Frédéric SWEENEY, Thomas Jay LOWERY, JR., Jessica Ann TOWNSEND, Jessica Lee SNYDER, Heidi Susanne GIESE, Cheryl Ann BANDOSKI-GRALINSKI, Daniella Lynn LOGAN
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Patent number: 9889449Abstract: The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics.Type: GrantFiled: May 10, 2016Date of Patent: February 13, 2018Assignee: ANDE CorporationInventors: Eugene Tan, Heung Chuan Lam, Valery Leonidovich Bogdanov, Gregory John Kellogg, John A. Wright, Ulrich Hans Thomann, Richard F. Selden
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Publication number: 20170100718Abstract: The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics.Type: ApplicationFiled: May 10, 2016Publication date: April 13, 2017Inventors: Eugene Tan, Heung Chuan Lam, Valery Leonidovich Bogdanov, Gregory John Kellogg, John A. Wright, Ulrich Hans Thomann, Richard F. Selden
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Patent number: 9366631Abstract: The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics.Type: GrantFiled: July 27, 2011Date of Patent: June 14, 2016Assignee: NetBio, Inc.Inventors: Eugene Tan, Heung Chuan Lam, Valery Leonidovich Bogdanov, Gregory John Kellogg, John A. Wright, Ulrich Hans Thomann, Richard F. Selden
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Publication number: 20130155403Abstract: The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics.Type: ApplicationFiled: July 27, 2011Publication date: June 20, 2013Applicant: NETBIO, INC.Inventors: Eugene Tan, Heung Chuan Lam, Valery Leonidovich Bogdanov, Gregory John Kellogg, John A. Wright, Ulrich Hans Thomann, Richard F. Selden
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Patent number: 8018593Abstract: The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics.Type: GrantFiled: April 4, 2008Date of Patent: September 13, 2011Assignee: NetBio, Inc.Inventors: Eugene Tan, Heung Chuan Lam, Valery Leonidovich Bogdanov, Gregory John Kellogg, John A. Wright, Ulrich Hans Thomann, Richard F. Selden
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Publication number: 20090059222Abstract: The present disclosure provides fully integrated microfluidic systems to perform nucleic acid analysis. These processes include sample collection, nucleic acid extraction and purification, amplification, sequencing, and separation and detection. The present disclosure also provides optical detection systems and methods for separation and detection of biological molecules. In particular, the various aspects of the invention enable the simultaneous separation and detection of a plurality of biological molecules, typically fluorescent dye-labeled nucleic acids, within one or a plurality of microfluidic chambers or channels. The nucleic acids can be labeled with at least 6 dyes, each having a unique peak emission wavelength. The present systems and methods are particularly useful for DNA fragment sizing applications such as human identification by genetic fingerprinting and DNA sequencing applications such as clinical diagnostics.Type: ApplicationFiled: April 4, 2008Publication date: March 5, 2009Applicant: Network Biosystems, Inc.Inventors: Eugene Tan, Heung Chuan Lam, Valery Leonidovich Bogdanov, Gregory John Kellogg, John A. Wright, Ulrich Hans Thomann, Richard F. Selden