Patents by Inventor Ulrich Reiser
Ulrich Reiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20220133734Abstract: The present invention encompasses compounds of formula (I) wherein the groups R1 to R4 and X1 to X5 have the meanings given in the claims and specification, their use as inhibitors of mutant EGFR, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.Type: ApplicationFiled: October 29, 2021Publication date: May 5, 2022Inventors: Harald ENGELHARDT, Mark PETRONCZKI, Juergen RAMHARTER, Ulrich REISER, Heinz STADTMUELLER, Dirk SCHARN, Tobias WUNBERG
-
Publication number: 20190358218Abstract: 6-Alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer.Type: ApplicationFiled: August 2, 2019Publication date: November 28, 2019Inventor: Ulrich REISER
-
Patent number: 10413536Abstract: 6-Alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer.Type: GrantFiled: September 26, 2017Date of Patent: September 17, 2019Assignee: Boehringer Ingelheim International GmbHInventor: Ulrich Reiser
-
Publication number: 20180015082Abstract: 6-Alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer.Type: ApplicationFiled: September 26, 2017Publication date: January 18, 2018Inventor: Ulrich REISER
-
Patent number: 9801871Abstract: 6-Alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer.Type: GrantFiled: October 3, 2016Date of Patent: October 31, 2017Assignee: Boehringer Ingelheim International GmbHInventor: Ulrich Reiser
-
Publication number: 20170020859Abstract: 6-Alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer.Type: ApplicationFiled: October 3, 2016Publication date: January 26, 2017Inventor: Ulrich REISER
-
Patent number: 9481673Abstract: 6-Alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer.Type: GrantFiled: August 10, 2015Date of Patent: November 1, 2016Assignee: Boehringer ingelheim International GmbHInventor: Ulrich Reiser
-
Patent number: 9422290Abstract: Disclosed are compounds of general formula (I) wherein the groups R1 to R3 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.Type: GrantFiled: November 11, 2013Date of Patent: August 23, 2016Assignee: Boehringer Ingelheim International GmbHInventors: Harald Engelhardt, Davide Gianni, Dirk Kessler, Ulrich Reiser, Christian Smethurst, Andreas Steffen
-
Patent number: 9278978Abstract: This invention relates to 6-alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R5 have the meanings given in the claims and in the specification.Type: GrantFiled: August 20, 2014Date of Patent: March 8, 2016Assignee: Boehringer Ingelheim International GmbHInventors: Ulrich Reiser, James Madden
-
Publication number: 20160039814Abstract: 6-Alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer.Type: ApplicationFiled: August 10, 2015Publication date: February 11, 2016Inventor: Ulrich REISER
-
Patent number: 9249151Abstract: This invention relates to bis-amido pyridines of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R4 have the meanings given in the claims and in the specification.Type: GrantFiled: August 20, 2014Date of Patent: February 2, 2016Assignee: Boehringer Ingelheim International GmbHInventor: Ulrich Reiser
-
Patent number: 9199988Abstract: The present invention encompasses compounds of general formula (I) wherein the groups R1 to R4 and A1 to A5 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.Type: GrantFiled: March 26, 2014Date of Patent: December 1, 2015Assignee: Boehringer Ingelheim International GmbHInventors: Christian Smethurst, Harald Engelhardt, Davide Gianni, Ulrich Reiser
-
Publication number: 20150057286Abstract: This invention relates to bis-amido pyridines of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R4 have the meanings given in the claims and in the specification.Type: ApplicationFiled: August 20, 2014Publication date: February 26, 2015Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventor: Ulrich REISER
-
Publication number: 20150057295Abstract: This invention relates to 6-alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R5 have the meanings given in the claims and in the specification.Type: ApplicationFiled: August 20, 2014Publication date: February 26, 2015Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Ulrich REISER, James MADDEN
-
Patent number: 8859541Abstract: 6-Alkynylpyridines which are SMAC mimetics and are useful as medicaments for the treatment of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The following compounds are exemplary: methyl 5-[6-[[2-(methylamino)propanoyl]amino]-2-[2-(3-methylphenyl)ethynyl]pyridin-3-yl]-pyridine-3-carboxylate and 2-(methylamino)-N-[5-(2-methylimidazo[1,2-a]pyridin-3-yl)-6-[2-(1-methyl-2-oxoquinolin-6-yl)-ethynyl]pyridin-2-yl]propanamid.Type: GrantFiled: February 19, 2013Date of Patent: October 14, 2014Assignee: Boehringer Ingelheim International GmbHInventors: Ulrich Reiser, Gerd Bader, Walter Spevak, Andreas Steffen, Alastair L. Parkes
-
Patent number: 8853420Abstract: The present invention encompasses compounds of general formula (1), wherein R1 to R4 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and their use for preparing a medicament having the above-mentioned properties.Type: GrantFiled: July 28, 2009Date of Patent: October 7, 2014Assignee: Boehringer Ingelheim International GmbHInventors: Matthias Treu, Thomas Karner, Ulrich Reiser
-
Publication number: 20140296230Abstract: The present invention encompasses compounds of general formula (I) wherein the groups R1 to R4 and A1 to A5 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.Type: ApplicationFiled: March 26, 2014Publication date: October 2, 2014Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Christian SMETHURST, Harald ENGELHARDT, Davide GIANNI, Ulrich REISER
-
Publication number: 20140135336Abstract: Disclosed are compounds of general formula (I) wherein the groups R1 to R3 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.Type: ApplicationFiled: November 11, 2013Publication date: May 15, 2014Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Harald ENGELHARDT, Davide GIANNI, Dirk KESSLER, Ulrich REISER, Christian SMETHURST, Andreas STEFFEN
-
Publication number: 20140018372Abstract: A crystalline form of 3-{3-[1-(4-Dimethylaminomethyl-phenylamino)-1-phenyl-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indol-6-yl}-propynoic acid ethylamide.Type: ApplicationFiled: July 9, 2013Publication date: January 16, 2014Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Gerd-Michael MAIER, Anke BAUM, Bodo BETZEMEIER, Manuel HENRY, Rolf HERTER, Ulrich REISER, Patrizia SINI, Dirk WEBER, Ulrike WERTHMANN, Stephan Karl ZAHN
-
Patent number: D813281Type: GrantFiled: October 15, 2015Date of Patent: March 20, 2018Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Ralf Kittmann, Sven Feustel, Tim Frohlich, Ulrich Reiser, Ralf-Simon King, Martin Hagele