Patents by Inventor Ulrich Schlecht

Ulrich Schlecht has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210310048
    Abstract: The invention comprises circular single-stranded templates for nucleic acid sequencing, methods of making and using the same.
    Type: Application
    Filed: June 16, 2021
    Publication date: October 7, 2021
    Inventors: Janine Mok, Ulrich Schlecht
  • Publication number: 20210246440
    Abstract: A novel method for preparing sequence-verified oligonucleotides is disclosed. In particular, the invention relates to a simple, affordable, and scalable method that combines high-throughput mating of yeast clones, a unique selectable system for combining DNA sequences in yeast, and next-generation sequencing. This method allows sequence-verified oligonucleotides to be readily isolated from complex libraries.
    Type: Application
    Filed: August 19, 2020
    Publication date: August 12, 2021
    Inventors: Robert P. St. Onge, Ulrich Schlecht, Sasha F. Levy, Ronald W. Davis, Joseph Horecka
  • Patent number: 11085068
    Abstract: The invention comprises circular single-stranded templates for nucleic acid sequencing, methods of making and using the same.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: August 10, 2021
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Janine Mok, Ulrich Schlecht
  • Publication number: 20210230611
    Abstract: Methods for identifying biosynthetic gene clusters that include genes for producing compounds that interact with specific target proteins are disclosed. Some methods relate to bioinformatics methods for identifying and/or prioritizing biosynthetic gene clusters. Related systems, components, and tools for the identification and expression of such gene clusters are also disclosed.
    Type: Application
    Filed: January 26, 2021
    Publication date: July 29, 2021
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Brian Thomas Naughton, Colin Harvey, Ulrich Schlecht, Maureen Elizabeth Hillenmeyer, Joe Horecka
  • Patent number: 10787661
    Abstract: A novel method for preparing sequence-verified oligonucleotides is disclosed. In particular, the invention relates to a simple, affordable, and scalable method that combines high-throughput mating of yeast clones, a unique selectable system for combining DNA sequences in yeast, and next-generation sequencing. This method allows sequence-verified oligonucleotides to be readily isolated from complex libraries.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: September 29, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Robert P. St. Onge, Ulrich Schlecht, Sasha F. Levy, Ronald W. Davis, Joseph Horecka
  • Publication number: 20200291411
    Abstract: Inducible promoters for the coordinated expression of at least one heterologous gene in yeast and methods of using them are disclosed. In particular, the invention relates to sets of inducible promoters derived from S. cerevisiae and related species that can be induced in the presence of nonfermentable carbon sources.
    Type: Application
    Filed: February 20, 2020
    Publication date: September 17, 2020
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Colin Harvey, Ulrich Schlecht, Maureen Elizabeth Hillenmeyer
  • Publication number: 20200282392
    Abstract: The present disclosure generally relates to devices for effecting epitachophoresis. Epitachophoresis may be used to effect sample analysis, such as by selective separation, detection, extraction, and/or pre-concentration of target analytes such as, for example, DNA, RNA, and/or other biological molecules. Said target analytes may be collected following epitachophoresis and used for desired downstream applications and further analysis.
    Type: Application
    Filed: November 13, 2018
    Publication date: September 10, 2020
    Inventors: Yann ASTIER, Jan BERKA, Ulrich SCHLECHT, Frantisek FORET, Vladimira DATINSKA, Ivona VORACOVA
  • Publication number: 20200208208
    Abstract: The invention is a novel method of making and using a library such as a sequencing library of single stranded circular nucleic acid templates via splint ligation.
    Type: Application
    Filed: March 9, 2020
    Publication date: July 2, 2020
    Inventors: Michael George, Jenny A. Johnson, Duylinh Nguyen, Ulrich Schlecht
  • Patent number: 10612032
    Abstract: Inducible promoters for the coordinated expression of at least one heterologous gene in yeast and methods of using them are disclosed. In particular, the invention relates to sets of inducible promoters derived from S. cerevisiae and related species that can be induced in the presence of nonfermentable carbon sources.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: April 7, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Colin Harvey, Ulrich Schlecht, Maureen Elizabeth Hillenmeyer
  • Publication number: 20200040347
    Abstract: Methods for identifying biosynthetic gene clusters that include genes for producing compounds that interact with specific target proteins are disclosed. Some methods relate to bioinformatics methods for identifying and/or prioritizing biosynthetic gene clusters. Related systems, components, and tools for the identification and expression of such gene clusters are also disclosed.
    Type: Application
    Filed: November 16, 2017
    Publication date: February 6, 2020
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Brian Thomas Naughton, Colin Harvey, Ulrich Schlecht, Maureen Elizabeth Hillenmeyer, Joe Horecka
  • Publication number: 20200010875
    Abstract: The invention comprises a novel method and compositions for sequencing library preparation, which increases the throughput of single-molecule sequencing (SMS) platforms by generating long concatenated templates from pools of short DNA molecules.
    Type: Application
    Filed: June 17, 2019
    Publication date: January 9, 2020
    Inventors: Janine Mok, Ulrich Schlecht, Austin So
  • Publication number: 20190176153
    Abstract: The present invention generally relates to a method which makes use of electrowetting to automate PCR amplification wherein the PCR reagents are contained in droplets, and further wherein the quantity of PCR product is monitored in real time thus enabling stopping amplification once a desired quantity of PCR product has been generated.
    Type: Application
    Filed: May 18, 2017
    Publication date: June 13, 2019
    Inventors: Jaeyoung YANG, Yann ASTIER, Janine MOK, Ulrich SCHLECHT
  • Publication number: 20190153514
    Abstract: The invention comprises circular single-stranded templates for nucleic acid sequencing, methods of making and using the same.
    Type: Application
    Filed: January 18, 2019
    Publication date: May 23, 2019
    Inventors: Janine Mok, Ulrich Schlecht
  • Publication number: 20170275635
    Abstract: Inducible promoters for the coordinated expression of at least one heterologous gene in yeast and methods of using them are disclosed. In particular, the invention relates to sets of inducible promoters derived from S. cerevisiae and related species that can be induced in the presence of nonfermentable carbon sources.
    Type: Application
    Filed: March 24, 2017
    Publication date: September 28, 2017
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Colin Harvey, Ulrich Schlecht, Maureen Elizabeth Hillenmeyer
  • Publication number: 20160122748
    Abstract: A novel method for preparing sequence-verified oligonucleotides is disclosed. In particular, the invention relates to a simple, affordable, and scalable method that combines high-throughput mating of yeast clones, a unique selectable system for combining DNA sequences in yeast, and next-generation sequencing. This method allows sequence-verified oligonucleotides to be readily isolated from complex libraries.
    Type: Application
    Filed: October 30, 2015
    Publication date: May 5, 2016
    Inventors: Robert P. St. Onge, Ulrich Schlecht, Sasha F. Levy, Ronald W. Davis, Joseph Horecka
  • Patent number: 8030100
    Abstract: The application relates to a chemical sensor device comprising a substrate (1), a sensor medium (3) formed on the substrate, the sensor medium comprising one-dimensional nanoparticles, wherein the one-dimensional nanoparticles essentially consist of a semiconducting AxBy compound, e.g. V2O5 and detection means (2) for detecting a change of a physical property of the sensor medium e.g. conductivity. The porosity of the sensor medium supports a fast access of the analyte to the sensing material and therefore a fast response of the sensor. The selectivity and sensitivity of the sensor can be tailored by doping the one-dimensional nanoscale material with different dopants or by varying the dopant concentration. Sensitivity of the sensor device to an analyte, preferably an amine, can be increased by increasing relative humidity of the sample to at least 5%.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: October 4, 2011
    Assignee: Sony Deutschland GmbH
    Inventors: Isabelle Besnard, Tobias Vossmeyer, Akio Yasuda, Marko Burghard, Ulrich Schlecht
  • Publication number: 20110104824
    Abstract: A sensor chip for specific analysis of analytes in a liquid includes a plurality of sensor elements based on the SAW principle and applied as layer structures onto a surface of a substrate. A surface of each sensor element is coated with a sensitive substrate or coating having receptors specifically binding one analyte. During operation, the surface of the sensor chip rests against and seals a half-open covering part, with the covering part and the sensor chip forming a flow cell to be rinsed by the liquid. Conductor structures contact the sensor elements from the flow cell. More than six sensor elements are present which can each be triggered and read out separately via control and measuring electronics. At least two and in particular all sensor elements, are each coated with a differently sensitive substrate and the sensitive substrate is applied to the surface before attachment of the cover part.
    Type: Application
    Filed: June 8, 2009
    Publication date: May 5, 2011
    Applicant: BIOSENSOR GMBH
    Inventors: Markus Perpeet, Ulrich Schlecht
  • Publication number: 20090227059
    Abstract: The application relates to a chemical sensor device comprising a substrate (1), a sensor medium (3) formed on the substrate, the sensor medium comprising one-dimensional nanoparticles, wherein the one-dimensional nanoparticles essentially consist of a semiconducting AxBy compound, e.g. V2O5 and detection means (2) for detecting a change of a physical property of the sensor medium e.g. conductivity. The porosity of the sensor medium supports a fast access of the analyte to the sensing material and therefore a fast response of the sensor. The selectivity and sensitivity of the sensor can be tailored by doping the one-dimensional nanoscale material with different dopants or by varying the dopant concentration. Sensitivity of the sensor device to an analyte, preferably an amine, can be increased by increasing relative humidity of the sample to at least 5%.
    Type: Application
    Filed: March 26, 2009
    Publication date: September 10, 2009
    Applicants: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG..., Sony Deutschland GmbH
    Inventors: Isabelle BESNARD, Tobias VOSSMEYER, Akio YASUDA, Marko BURGHARD, Ulrich SCHLECHT
  • Patent number: 7531136
    Abstract: The application relates to a chemical sensor device comprising a substrate (1), a sensor medium (3) formed on the substrate, the sensor medium comprising one-dimensional nanoparticles, wherein the one-dimensional nanoparticles essentially consist of a semiconducting AxBy compound, e.g. V2O5 and detection means (2) for detecting a change of a physical property of the sensor medium e.g. conductivity. The porosity of the sensor medium supports a fast access of the analyte to the sensing material and therefore a fast response of the sensor. The selectivity and sensitivity of the sensor can be tailored by doping the one-dimensional nanoscale material with different dopants or by varying the dopant concentration. Sensitivity of the sensor device to an analyte, preferably an amine, can be increased by increasing relative humidity of the sample to at least 5%.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: May 12, 2009
    Assignees: Sony Deutschland GmbH, Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Isabelle Besnard, Tobias Vossmeyer, Akio Yasuda, Marko Burghard, Ulrich Schlecht
  • Publication number: 20090084162
    Abstract: The application relates to a chemical sensor device comprising a substrate (1), a sensor medium (3) formed on the substrate, the sensor medium comprising one-dimensional nanoparticles, wherein the one-dimensional nanoparticles essentially consist of a semiconducting AxBy compound, e.g. V2O5 and detection means (2) for detecting a change of a physical property of the sensor medium e.g. conductivity. The porosity of the sensor medium supports a fast access of the analyte to the sensing material and therefore a fast response of the sensor. The selectivity and sensitivity of the sensor can be tailored by doping the one-dimensional nanoscale material with different dopants or by varying the dopant concentration. Sensitivity of the sensor device to an analyte, preferably an amine, can be increased by increasing relative humidity of the sample to at least 5%.
    Type: Application
    Filed: February 14, 2006
    Publication date: April 2, 2009
    Applicants: SONY INTERNATIONAL (EUROPE) GMBH, MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V.
    Inventors: Isabelle Besnard, Tobias Vossmeyer, Akio Yasuda, Marko Burghard, Ulrich Schlecht