Patents by Inventor Utz-Peter Jagusch

Utz-Peter Jagusch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8704002
    Abstract: Process for the preparation of substituted dimethyl-(3-aryl-butyl)-amine compounds. The process comprises dehydration by heterogeneous catalysis of substituted 4-dimethylamino-2-aryl-butan-2-ol compounds, to form substituted dimethyl-(3-aryl-but-3-enyl)-amine intermediates, which are then converted by hydrogenation with hydrogen to substituted dimethyl-(3-aryl-butyl)-amine compounds.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: April 22, 2014
    Assignee: Grünenthal GmbH
    Inventors: Utz-Peter Jagusch, Wolfgang Hoelderich, Monika Voerckel
  • Patent number: 8106055
    Abstract: Substituted amide compounds corresponding to formula I: processes for preparing them, pharmaceutical compositions containing these compounds, and the use of substituted amide derivatives for the preparation of medicaments for the treatment of pain and various other conditions.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: January 31, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Utz-Peter Jagusch, Beatrix Merla, Stefan Schunk, Werner Englberger, Timo Struenker, Hagen-Heinrich Hennies, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Patent number: 7842812
    Abstract: Substituted 5-aminomethyl-1H-pyrrole-2-carboxylic acid amides, a process for the production thereof, pharmaceutical preparations containing these compounds and the use of these compounds in pharmaceutical preparations for treatment or inhibition of withdrawal symptoms, memory disorders, neurodegenerative diseases, epilepsy, cardiovascular disorders, water retention, intestinal motility disorders, urinary incontinence, anorexia, tinnitus, pruritus, depression, sexual dysfunction, airways diseases, food intake disorders, or type II (non-insulin-dependent) diabetes, or for anxiolysis, diuresis, suppression of the urinary reflex, reducing the addictive potential of opioids, modulating locomotor activity, influencing the cardiovascular system, or regulating electrolyte balance.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: November 30, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies, Babette-Yvonne Koegel
  • Patent number: 7776903
    Abstract: Pharmaceutical preparations containing substituted 2,5-diaminomethyl-1H-pyrrole compounds corresponding to formula I, and the use of these compounds for the production of pharmaceutical preparations and in related treatment methods.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: August 17, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies
  • Publication number: 20080312301
    Abstract: The invention relates to substituted N-benzo[d]isoxazol-3-yl-amine derivatives of formula (I) wherein R1, R2, R3, R4 and R5 are defined as in patent claim 1. The invention also relates to the use of said compounds for producing medicaments.
    Type: Application
    Filed: June 6, 2006
    Publication date: December 18, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix Merla, Matthias Gerlach, Corinna Sundermann, Utz-Peter Jagusch, Hagen-Heinrich Hennies, Stefan Oberborsch, Michael Haurand, Ruth Jostock, Melanie Reich
  • Publication number: 20080306084
    Abstract: Substituted amide compounds corresponding to formula I: processes for preparing them, pharmaceutical compositions containing these compounds, and the use of substituted amide derivatives for the preparation of medicaments for the treatment of pain and various other conditions.
    Type: Application
    Filed: April 30, 2008
    Publication date: December 11, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Utz-Peter Jagusch, Beatrix Merla, Stefan Schunk, Werner Englberger, Timo Struenker, Hagen-Heinrich Hennies, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Publication number: 20070135403
    Abstract: Substituted 2,5-diaminomethyl-1H-pyrroles, a process for the production thereof, pharmaceutical compositions containing them, and the use of these compounds for regulating 5-hydroxytryptamine uptake, noradrenalin uptake and/or opioid receptor activity, or for treating or inhibiting disorders or diseases at least partially mediated by a receptor selected from the group consisting of 5-hydroxytryptamine receptors, noradrenalin receptors and opioid receptors.
    Type: Application
    Filed: November 17, 2006
    Publication date: June 14, 2007
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies
  • Publication number: 20070135494
    Abstract: Substituted 5-aminomethyl-1H-pyrrole-2-carboxylic acid amides, a process for the production thereof, pharmaceutical preparations containing these compounds and the use of these compounds in pharmaceutical preparations for treatment or inhibition of withdrawal symptoms, memory disorders, neurodegenerative diseases, epilepsy, cardiovascular disorders, water retention, intestinal motility disorders, urinary incontinence, anorexia, tinnitus, pruritus, depression, sexual dysfunction, airways diseases, food intake disorders, or type II (non-insulin-dependent) diabetes, or for anxiolysis, diuresis, suppression of the urinary reflex, reducing the addictive potential of opioids, modulating locomotor activity, influencing the cardiovascular system, or regulating electrolyte balance.
    Type: Application
    Filed: November 17, 2006
    Publication date: June 14, 2007
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies, Babette-Yvonne Kogel
  • Patent number: 7229991
    Abstract: 5-aminomethyl-1H-pyrrole-2-carboxylic acid amide compounds corresponding to formula I and processes for the production thereof. Pharmaceutical preparations containing these compounds and the use of these compounds for the production of pharmaceutical preparations and in related treatment methods.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: June 12, 2007
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies, Babette-Yvonne Kögel
  • Patent number: 7230103
    Abstract: Substituted 3,4-dihydropyrido[1,2-a]pyrimidines of formula I and processes for the production thereof Also disclosed are substance libraries and pharmaceutical compositions containing the compound, and methods of treatment for pain, urinary incontinence, pruritus, tinnitus and/or diarrhoea using the pharmaceutical composition.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: June 12, 2007
    Assignee: Gruenenthal GmbH
    Inventors: Matthias Gerlach, Corinna Maul, Utz-Peter Jagusch
  • Patent number: 7226924
    Abstract: Substituted 3,4-dihydro-pyrimido[1,2a]pyrimidines and 3,4-dihydro-pyrazino[1,2a]pyrimidines of general formula I, the invention also relates to a method for the production thereof, substance libraries containing these compounds, medicaments which contain these compounds in the production of medicaments for treating pain, urinary incontinence, itching, tinnitus aurium and/or diarrhea and to pharmaceutical compositions containing these compounds.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: June 5, 2007
    Assignee: Gruenenthal GmbH
    Inventors: Matthias Gerlach, Corinna Maul, Utz-Peter Jagusch
  • Patent number: 7199130
    Abstract: Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]fluorene-6-carboxylic acid compounds, and processes for the production thereof, pharmaceutical compositions containing these compounds and the use thereof in treatment methods and for the production of pharmaceutical preparations for specific indications, in particular for the treatment of pain.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: April 3, 2007
    Assignee: Gruenenthal GmbH
    Inventors: Matthias Gerlach, Michael Przewosny, Werner Guenter Englberger, Elke Reissmueller, Petra Bloms-Funke, Corinna Maul, Utz-Peter Jagusch
  • Patent number: 7135568
    Abstract: Substituted pyrazolopyrimidines and thiazolopyrimidines, specifically, compounds corresponding to the structure (I A), (I B) or (II) processes for their preparation, substance libraries containing them, pharmaceutical formulations containing these compounds, the use of these compounds for the production of medicaments for the treatment and/or prophylaxis of pain and related treatment methods are provided.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: November 14, 2006
    Assignee: Gruenenthal GmbH
    Inventors: Matthias Gerlach, Corrinna Sundermann, Utz-Peter Jagusch, Bernd Sundermann, Martin Fuhr, Adriaan P. Ijzerman, Miriam Dissen-De Groote
  • Publication number: 20060167318
    Abstract: Process for the preparation of substituted dimethyl-(3-aryl-butyl)-amine compounds. The process comprises dehydration by heterogeneous catalysis of substituted 4-dimethylamino-2-aryl-butan-2-ol compounds, to form substituted dimethyl-(3-aryl-but-3-enyl)-amine intermediates, which are then converted by hydrogenation with hydrogen to substituted dimethyl-(3-aryl-butyl)-amine compounds.
    Type: Application
    Filed: December 22, 2005
    Publication date: July 27, 2006
    Applicant: Gruenenthal GmbH
    Inventors: Utz-Peter Jagusch, Wolfgang Hoelderich, Monika Wissler
  • Patent number: 7022739
    Abstract: Substituted 1-aminobutane-3-ol compounds, methods for producing them, pharmaceutical compounds containing them, and the use of substituted 1-aminobutane-3-ol compounds for producing pharmaceutical compounds.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: April 4, 2006
    Assignee: Gruenenthal GmbH
    Inventors: Helmut Buschmann, Corinna Maul, Bernd Sundermann, Utz-Peter Jagusch, Michael Haurand, Boris Chizh
  • Publication number: 20050288342
    Abstract: 5-aminomethyl-1H-pyrrole-2-carboxylic acid amide compounds corresponding to formula I and processes for the production thereof. Pharmaceutical preparations containing these compounds and the use of these compounds for the production of pharmaceutical preparations and in related treatment methods.
    Type: Application
    Filed: June 20, 2005
    Publication date: December 29, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies, Babette-Yvonne Kögel
  • Publication number: 20050272782
    Abstract: Pharmaceutical preparations containing substituted 2,5-diaminomethyl-1H-pyrrole compounds corresponding to formula I, and the use of these compounds for the production of pharmaceutical preparations and in related treatment methods.
    Type: Application
    Filed: June 20, 2005
    Publication date: December 8, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies
  • Publication number: 20040248889
    Abstract: Substituted 5,6,6a, 11b-tetrahydro-7-oxa-5-aza-benzo[c]fluorene-6-carboxylic acid compounds, and processes for the production thereof, pharmaceutical compositions containing these compounds and the use thereof in treatment methods and for the production of pharmaceutical preparations for specific indications, in particular for the treatment of pain.
    Type: Application
    Filed: February 3, 2004
    Publication date: December 9, 2004
    Applicant: Gruenenthal GmbH
    Inventors: Matthias Gerlach, Michael Przewosny, Werner Guenter Englberger, Elke Reissmueller, Petra Bloms-Funke, Corinna Maul, Utz-Peter Jagusch
  • Patent number: 6815443
    Abstract: The invention relates to 5-amino-1-pentene-3-ol substituted derivatives, a method for the production thereof, medicaments containing said compounds, the use of substituted 5-amino-1-pentene-3-ol derivatives for the production of medicaments, and methods of treatment using the medicaments.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: November 9, 2004
    Assignee: Gruenenthal GmbH
    Inventors: Helmut Buschmann, Corinna Maul, Bernd Sundermann, Utz-Peter Jagusch, Michael Haurand, Boris Chizh
  • Publication number: 20040127508
    Abstract: Substituted pyrazolopyrimidines and thiazolopyrimidines are provided along with methods for production, treatment of medical conditions and illnesses, and formulations for use as pharmaceutical compositions.
    Type: Application
    Filed: September 12, 2003
    Publication date: July 1, 2004
    Inventors: Matthias Gerlach, Corrinna Maul, Utz-Peter Jagusch, Bernd Sundermann, Martin Fuhr, Adriaan P. Ijzerman, Miriam Dissen-De Groote