Patents by Inventor Valerie Brault

Valerie Brault has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT
    Publication number: 20120316201
    Abstract: The invention relates to novel benzimidazole and imidazopyridine derivatives having the general Formula (I), which have a good affinity with certain subtypes of melanocortin receptors, particularly MC4 receptors. The derivatives are particularly suitable for the treatment of pathological states and diseases involving one or more melanocortin receptors. The invention also relates to pharmaceutical compositions containing said the compounds having the general Formula (I).
    Type: Application
    Filed: June 8, 2012
    Publication date: December 13, 2012
    Applicant: IPSEN PHARMA S.A.S.
    Inventors: Lÿdie POITOUT, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Pyrimido-benzimidzole derivatives and the use thereof in the form of agonists or antagonists of melanocortin receptors
    Patent number: 8288395
    Abstract: The invention relates to novel pyrimido-benzimidazole derivatives. Said products exhibit a good affinity for certain melanocortin receptor sub-types, in particular MC4 receptors. Said products represent a particular interest for treating pathological disorders and diseases associated with one or several melanocortin receptors. Pharmaceutical compositions containing said products and the use thereof for a drug preparation are also disclosed.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: October 16, 2012
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Lydie Poitout, Carole Sackur, Valerie Brault, Pierre Roubert, Pascale Plas
  • Benzimidazole derivatives and their use as a medicament
    Patent number: 8236965
    Abstract: A subject of the present application is new benzimidazole derivatives of formula in which A, Y, R1, R2, R3 and R4 represent different variable groups. These products have an antagonist activity of GnRH (Gonadotropin-Releasing Hormone). The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: August 7, 2012
    Assignee: IPSEN Pharma S.A.S.
    Inventors: Lydie Poitout, Valérie Brault, Eric Ferrandis, Christophe Thurieau
  • Benzimidazole and imidazopyridine derivatives and use thereof as a medicament
    Patent number: 8227485
    Abstract: The invention relates to novel benzimidazole and imidazopyridine derivatives having general formula (I), which have a good affinity with certain sub-types of melanocortin receptors, particularly MC4 receptors. Said derivatives are particularly suitable for the treatment of pathological states and diseases involving one or more melanocortin receptors. The invention also relates to pharmaceutical compositions containing said products.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: July 24, 2012
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Lydie Poitout, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Derivatives of benzimidazole and imidazo-pyridine and their use as medicaments
    Patent number: 7816539
    Abstract: A subject of the present Application is novel derivatives of benzimidazole and imidazopyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular the MC4 receptors. They are particularly useful for treating pathological conditions and diseases in which one or more melanocortin receptors are involved. The invention also relates to pharmaceutical compositions containing said products.
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: October 19, 2010
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Lydie Poitout, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • PYRIMIDO-BENZIMIDZOLE DERIVATIVES AND THE USE THEREOF IN THE FORM OF AGONISTS OR ANTAGONISTS OF MELANOCORTIN RECEPTORS
    Publication number: 20100256135
    Abstract: The invention relates to novel pyrimido-benzimidazole derivatives. Said products exhibit a good affinity for certain melanocortin receptor sub-types, in particular MC4 receptors. Said products represent a particular interest for treating pathological disorders and diseases associated with one or several melanocortin receptors. Pharmaceutical compositions containing said products and the use thereof for a drug preparation are also disclosed.
    Type: Application
    Filed: June 17, 2010
    Publication date: October 7, 2010
    Applicant: IPSEN PHARMA S.A.S.
    Inventors: Lydie POITOUT, Carole Sackur, Valérie Brault, Pierre Roubert, Pascale Plas
  • Pyrimido-benzimidazole derivatives and the use thereof in the form of agonists and antagonists of melanocortin receptors
    Patent number: 7763725
    Abstract: The invention relates to novel pyrimido-benzimidazole derivatives. Said products exhibit a good affinity for certain melanocortin receptor sub-types, in particular MC4 receptors. Said products represent a particular interest for treating pathological disorders and diseases associated with one or several melanocortin receptors. Pharmaceutical compositions containing said products and the use thereof for a drug preparation are also disclosed.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: July 27, 2010
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Lydie Poitout, Carole Sackur, Valerie Brault, Pierre Roubert, Pascale Plas
  • DERIVATIVES OF IMIDAZO PYRIMIDO AND DIAZEPINE PYRIMIDINE-DIONE, AND USE THEREOF AS A DRUG
    Publication number: 20100144714
    Abstract: The present invention relates to new derivatives of imidazo, pyrimido and diazepine-pyrimidine-dione of the general formula (I) in which R1, R2, L1, L2, Y, Z and A are various and varying groups. These products exhibit a good affinity for certain sub-types of cannabinoid receptors, in particular the CB2 receptors. They are particularly useful for treating pathological conditions and diseases in which one or more cannabinoid receptors are involved. The invention also relates to pharmaceutical compositions containing said products, and to the use thereof for preparing a drug.
    Type: Application
    Filed: December 17, 2007
    Publication date: June 10, 2010
    Applicant: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valérie Brault
  • NOVEL DERIVATIVES OF BENZIMIDAZOLE AND IMIDAZO-PYRIDINE AND THEIR USE AS MEDICAMENTS
    Publication number: 20090270372
    Abstract: A subject of the present Application is novel derivatives of benzimidazole and imidazopyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular the MC4 receptors. They are particularly useful for treating pathological conditions and diseases in which one or more melanocortin receptors are involved. The invention also relates to pharmaceutical compositions containing said products.
    Type: Application
    Filed: January 21, 2009
    Publication date: October 29, 2009
    Applicant: Societe de Conseils de Recherches et
    Inventors: Lydie POITOUT, Valerie Brault, Carole Sackur, Roubert Pierre, Pascale Plas
  • Pyrimido-Benzimidazole Derivatives and the Use Thereof in the Form of Agonists and Antagonists of Melanocortin Receptors
    Publication number: 20090209531
    Abstract: The invention relates to novel pyrimido-benzimidazole derivatives. Said products exhibit a good affinity for certain melanocortin receptor sub-types, in particular MC4 receptors. Said products represent a particular interest for treating pathological disorders and diseases associated with one or several melanocortin receptors. Pharmaceutical compositions containing said products and the use thereof for a drug preparation are also disclosed.
    Type: Application
    Filed: June 22, 2005
    Publication date: August 20, 2009
    Inventors: Lydie Poitout, Carole Sackur, Valerie Brault, Pierre Roubert, Pascale Plas
  • Benzimidazole derivatives and their use as a medicament
    Publication number: 20090170922
    Abstract: A subject of the present application is new benzimidazole derivatives of formula in which A, Y, R1, R2, R3 and R4 represent different variable groups. These products have an antagonist activity of GnRH (Gonadotropin-Releasing Hormone). The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.
    Type: Application
    Filed: December 23, 2008
    Publication date: July 2, 2009
    Inventors: Lydie Poitout, Valerie Brault, Eric Ferrandis, Christophe Thurieau
  • Derivatives of benzimidazole and imidazo-pyridine and their use as medicaments
    Patent number: 7501524
    Abstract: A compound of the formula wherein the substituents are as defined in the specification and pharmaceutical salts thereof having a good affinity for sub-types of melanocortin receptors making them useful for treating diseases in which such receptors are included such as pain, inflammatory conditions, etc.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: March 10, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Derivatives of benzimidazole and their use as medicaments
    Patent number: 7501525
    Abstract: A subject of the present Application is novel derivatives of benzimidazole and imidazo-pyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular the MC4 receptors. They are particularly useful for treating pathological conditions and diseases in which one or more melanocortin receptors are involved. The invention also relates to pharmaceutical compositions containing said products.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: March 10, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Imidazopyridine derivatives as melancortin receptor agonists
    Patent number: 7495009
    Abstract: Derivatives of imidazopyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular MC4 receptors and are useful for treating pathological states and diseases in which one or more melanocortin receptors are involved and pharmaceutical compositions containing said products.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: February 24, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valérie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Benzimidazole derivatives and their use as GnRH antagonists
    Patent number: 7495110
    Abstract: A subject of the present application is new benzimidazole derivatives of formula in which A, Y, R1, R2, R3 and R4 represent different variable groups. These products have an antagonist activity of GnRH (Gonadotropin-Releasing Hormone). The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: February 24, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valérie Brault, Eric Ferrandis, Christophe Thurieau
  • Novel derivatives of benzimidazale and imidazo-pyridine and their use as medicaments
    Publication number: 20080139619
    Abstract: A subject of the present application is novel derivatives of benzimidazole and imidazo-pyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular the MC4 receptors. They are particularly useful for treating pathological conditions and diseases in which one or more melanocortin receptors are involved. The invention also relates to pharmaceutical compositions containing said products.
    Type: Application
    Filed: January 31, 2008
    Publication date: June 12, 2008
    Inventors: Lydie Poitout, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Benzimidazole and imidazopyridine derivatives and use thereof as a medicament
    Patent number: 7355052
    Abstract: A compound of the formula wherein the substituents are as defined in the specification and pharmaceutical salts thereof having a good affinity for sub-types of melanocortin receptors making them useful for treating diseases in which such receptors are included such as pain, inflammatory conditions, etc.
    Type: Grant
    Filed: February 25, 2004
    Date of Patent: April 8, 2008
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Derivatives of hydantoins, thiohydantoins, pyrimidinediones and thioxopyrimidinones, their preparation processes and their use as medicaments
    Patent number: 7332517
    Abstract: A method of treating a disorder selected from the group consisting of acromegaly, hypophyseal adenomas, endocrine gastroenteropancreatic tumors including carcinoid syndrome and gastrointestinal bleeding in warm-blooded animals comprising administering to warm-blooded animals in need thereof an amount of a compound of the formula in racemic or enantiomeric form.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: February 19, 2008
    Assignee: Société de Conseils de Recheres et d'Applications Scientifiques (SCRAS)
    Inventors: Lydie Poitout, Valérie Brault, Christophe Thurieau
  • Derivatives of hydantoins, thiohydantoins, pyrimidinediones and thioxopyrimidinones, their preparation processes and their use as medicaments
    Patent number: 7199145
    Abstract: Compounds of the formula in racemic or enantiomeric forms wherein the substituents are as defined in the application. Useful for treating acromegalia, hypophyseal adenomas or endocrinic gastroenteropancreatic tumors.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: April 3, 2007
    Assignee: Societe de Conseils de Recherches et d' 'Applications Scientifiques (S.C.R.A.S)
    Inventors: Lydie Poitout, Valérie Brault, Christophe Thurieau
  • New derivatives of hydantoins, thiohydantoins, pyrimidinediones and thioxopyrimidinones, their preparation processes and their use as medicaments
    Publication number: 20070021420
    Abstract: A method of treating a disorder selected from the group consisting of acromegaly, hypophyseal adenomas, endocrine gastroenteropancreatic tumors including carcinoid syndrome and gastrointestinal bleeding in warm-blooded animals comprising administering to warm-blooded animals in need thereof an amount of a compound of the formula in racemic or enantiomeric form.
    Type: Application
    Filed: June 1, 2006
    Publication date: January 25, 2007
    Inventors: Lydie Poitout, Valerie Brault, Christophe Thurieau