Patents by Inventor Valerie C. Marcano

Valerie C. Marcano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Altered avian virus for in-ovo inoculation and methods of use thereof
    Patent number: 10196616
    Abstract: An altered avian NDV that contains the coding sequence of avian interleukin-4 (IL-4), or a portion thereof, in the reverse orientation suppresses in-ovo IL-4 production via RNAi when administered to embryonic birds. An immunogenic composition containing this altered NDV is included in this invention. The altered avian NDV can, optionally contain a polynucleotide encoding a heterologous antigen from a heterologous avian pathogen and can produce said heterologous antigen in-ovo.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: February 5, 2019
    Assignees: The United States of America, as represented by the Secretary of Agriculture, University of Georgia Research Foundation, Inc.
    Inventors: Claudio L. Afonso, Valerie C. Marcano, Nany Stivalis Cardenas Garcia, Qingzhong Yu, Tonya L. Taylor
  • ALTERED AVIAN VIRUS FOR IN-OVO INOCULATION AND METHODS OF USE THEREOF
    Publication number: 20180230439
    Abstract: An altered avian NDV that contains the coding sequence of avian interleukin-4 (IL-4), or a portion thereof, in the reverse orientation suppresses in-ovo IL-4 production via RNAi when administered to embryonic birds. An immunogenic composition containing this altered NDV is included in this invention. The altered avian NDV can, optionally contain a polynucleotide encoding a heterologous antigen from a heterologous avian pathogen and can produce said heterologous antigen in-ovo.
    Type: Application
    Filed: February 7, 2018
    Publication date: August 16, 2018
    Inventors: Claudio L. Afonso, Valerie C. Marcano, Nany Stivalis Cardenas Garcia, Qingzhong Yu, Tonya L. Taylor