Patents by Inventor Valery G. Kulichikhin
Valery G. Kulichikhin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10869947Abstract: Hydrogel compositions are provided (a) that have a continuous hydrophobic phase and a discontinuous hydrophilic phase, (b) that have a discontinuous hydrophilic phase and a continuous hydrophilic phase, or (c) that are entirely composed of a continuous hydrophilic phase. The hydrophobic phase, if present, is composed of a hydrophobic polymer, particularly a hydrophobic pressure-sensitive adhesive (PSA), a plasticizing elastomer, a tackifying resin, and an optional antioxidant. The discontinuous hydrophilic phase, if present, is composed of a crosslinked hydrophilic polymer, particularly a crosslinked cellulosic polymer such as crosslinked sodium carboxymethylcellulose. For those hydrogel compositions containing a continuous hydrophilic phase, the components of the phase include a cellulose ester composition or an acrylate polymer or copolymer, and a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding thereto.Type: GrantFiled: April 29, 2014Date of Patent: December 22, 2020Assignees: Corium, Inc., A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of SciencesInventors: Gary W. Cleary, Shoreh Parandoosh, Mikhail M. Feldstein, Anatoly E. Chalykh, Nicolai A. Platè, Valery G. Kulichikhin
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Patent number: 9259504Abstract: Hydrogel compositions are provided (a) that have a continuous hydrophobic phase and a discontinuous hydrophilic phase, (b) that have a discontinuous hydrophilic phase and a continuous hydrophilic phase, or (c) that are entirely composed of a continuous hydrophilic phase. The hydrophobic phase, if present, is composed of a hydrophobic polymer, particularly a hydrophobic pressure-sensitive adhesive (PSA), a plasticizing elastomer, a tackifying resin, and an optional antioxidant. The discontinuous hydrophilic phase, if present, is composed of a crosslinked hydrophilic polymer, particularly a crosslinked cellulosic polymer such as crosslinked sodium carboxymethylcellulose. For those hydrogel compositions containing a continuous hydrophilic phase, the components of the phase include a cellulose ester composition or an acrylate polymer or copolymer, and a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding thereto.Type: GrantFiled: May 10, 2013Date of Patent: February 16, 2016Assignees: A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.Inventors: Gary W. Cleary, Shoreh Parandoosh, Mikhail M. Feldstein, Anatoly E. Chalykh, Nicolai A. Platè, Valery G. Kulichikhin
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Patent number: 9242021Abstract: An adhesive composition is described which has improved initial tack, long-term adhesion, water uptake and translucency characteristics and may be prepared by melt extrusion. Uses of these compositions are also described, for example, their use as blister pads and wound dressings.Type: GrantFiled: August 4, 2005Date of Patent: January 26, 2016Assignees: Corium International, Inc., A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of SciencesInventors: Parminder Singh, Gary W. Cleary, Valery G. Kulichikhin, Sergey Antonov
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Patent number: 9144552Abstract: A rapidly dissolving film is provided for delivery of an active agent to a moist body surface, e.g., mucosal tissue. The film comprises a film-forming binder, a rapidly dissolving polymeric material, and an active agent.Type: GrantFiled: February 3, 2014Date of Patent: September 29, 2015Assignees: A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.Inventors: Parminder Singh, Sri Mudumba, Danir F. Bayramov, Valery G. Kulichikhin, Mikhail M. Feldstein, Gary W. Cleary
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Patent number: 9127140Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition in composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that non-covalently bind to the polar groups on the film-forming polymer, and plasticizer. A method for manufacturing the adhesive composition is provided as well.Type: GrantFiled: December 23, 2013Date of Patent: September 8, 2015Assignees: A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.Inventors: Mikhail M. Feldstein, Danir F. Bayramov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platè, Gary W. Cleary, Parminder Singh
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Publication number: 20140371692Abstract: Hydrogel compositions are provided (a) that have a continuous hydrophobic phase and a discontinuous hydrophilic phase, (b) that have a discontinuous hydrophilic phase and a continuous hydrophilic phase, or (c) that are entirely composed of a continuous hydrophilic phase. The hydrophobic phase, if present, is composed of a hydrophobic polymer, particularly a hydrophobic pressure-sensitive adhesive (PSA), a plasticizing elastomer, a tackifying resin, and an optional antioxidant. The discontinuous hydrophilic phase, if present, is composed of a crosslinked hydrophilic polymer, particularly a crosslinked cellulosic polymer such as crosslinked sodium carboxymethylcellulose. For those hydrogel compositions containing a continuous hydrophilic phase, the components of the phase include a cellulose ester composition or an acrylate polymer or copolymer, and a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding thereto.Type: ApplicationFiled: April 29, 2014Publication date: December 18, 2014Applicants: A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS RUSSIAN ACADEMY OF SCIENCES, CORIUM INTERNATIONAL, INC.Inventors: Gary W. Cleary, Shoreh Parandoosh, Mikhail M. Feldstein, Anatoly E. Chalykh, Nicolai A. Platè, Valery G. Kulichikhin
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Publication number: 20140322143Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition in composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that noncovalently bind to the polar groups on the film-forming polymer, and plasticizer. A method for manufacturing the adhesive composition is provided as well.Type: ApplicationFiled: December 23, 2013Publication date: October 30, 2014Applicants: CORIUM INTERNATIONAL, INC., A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCESInventors: Mikhail M. Feldstein, Danir F. Bayramov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platè, Gary W. Cleary, Parminder Singh
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Patent number: 8821901Abstract: A method of selecting components for use in water-absorbing pressure-sensitive adhesive compositions is provided. The method involves selecting a film-forming polymer, a ladder-like non-covalent crosslinker that is capable of forming a ladder-like interpolymer complex with the film-forming polymer selected, and selecting a carcass-like non-covalent crosslinker that is capable of forming a carcass-like complex with at least one of the film-forming polymer selected or the ladder-like non-covalent crosslinker selected. The adhesive hydrogels provide high adhesion in a swollen state and bridge the gap between conventional pressure sensitive adhesives and bioadhesives. Methods for preparing and using the resulting compositions are also disclosed.Type: GrantFiled: April 5, 2010Date of Patent: September 2, 2014Assignees: A.V. Topchiev Institute of Petrochemical Synthesis Russian Academy of Sciences, Corium International, Inc.Inventors: Mikhail M. Feldstein, Danir F. Bairamov, Nicolai A. Platé, Valery G. Kulichikhin, Anatoly E. Chalykh, Gary W. Cleary, Parminder Singh
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Patent number: 8753669Abstract: An adhesive composition is provided that contains both a hydrophobic phase and a hydrophilic phase, wherein the hydrophobic phase is composed of a hydrophobic polymer composition and the hydrophilic phase is a water-absorbent blend of a hydrophilic polymer and a complementary oligomer capable of crosslinking the hydrophilic polymer through hydrogen bonding, ionic bonding, and/or covalent bonding. The composition is useful as a bioadhesive, for affixing drug delivery systems, wound dressings, bandages, cushions, or the like to a body surface such as skin or mucosal tissue.Type: GrantFiled: August 20, 2007Date of Patent: June 17, 2014Assignees: A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.Inventors: Gary W. Cleary, Mikhail M. Feldstein, Valery G. Kulichikhin, Danir F. Bairamov
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Publication number: 20140147489Abstract: A rapidly dissolving film is provided for delivery of an active agent to a moist body surface, e.g., mucosal tissue. The film comprises a film-forming binder, a rapidly dissolving polymeric material, and an active agent.Type: ApplicationFiled: February 3, 2014Publication date: May 29, 2014Applicants: A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCES, CORIUM INTERNATIONAL, INC.Inventors: Parminder Singh, Sri Mudumba, Danir F. Bayramov, Valery G. Kulichikhin, Mikhail M. Feldstein, Gary W. Cleary
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Patent number: 8728445Abstract: Hydrogel compositions are provided (a) that have a continuous hydrophobic phase and a discontinuous hydrophilic phase, (b) that have a discontinuous hydrophilic phase and a continuous hydrophilic phase, or (c) that are entirely composed of a continuous hydrophilic phase. The hydrophobic phase, if present, is composed of a hydrophobic polymer, particularly a hydrophobic pressure-sensitive adhesive (PSA), a plasticizing elastomer, a tackifying resin, and an optional antioxidant. The discontinuous hydrophilic phase, if present, is composed of a crosslinked hydrophilic polymer, particularly a crosslinked cellulosic polymer such as crosslinked sodium carboxymethylcellulose. For those hydrogel compositions containing a continuous hydrophilic phase, the components of the phase include a cellulose ester composition or an acrylate polymer or copolymer, and a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding thereto.Type: GrantFiled: May 1, 2002Date of Patent: May 20, 2014Assignees: A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.Inventors: Gary W. Cleary, Shoreh Parandoosh, Mikhail M. Feldstein, Anatoly E. Chalykh, Nicolai A. Platé, Valery G. Kulichikhin
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Patent number: 8658201Abstract: A rapidly dissolving film is provided for delivery of an active agent to a moist body surface, e.g., mucosal tissue. The film comprises a film-forming binder, a rapidly dissolving polymeric material, and an active agent.Type: GrantFiled: January 31, 2005Date of Patent: February 25, 2014Assignees: Corium International, Inc., A.V. Topchiev Institute of Petrochemical Syntheses, Russian Academy of SciencesInventors: Parminder Singh, Sri Mudumba, Danir R. Bairamov, Valery G. Kulichikhin, Mikhail M. Feldstein, Gary W. Cleary
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Patent number: 8617647Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition in composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that noncovalently bind to the polar groups on the film-forming polymer, and plasticizer. A method for manufacturing the adhesive composition is provided as well.Type: GrantFiled: August 24, 2012Date of Patent: December 31, 2013Assignees: A.V. Topchiev Institutes of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.Inventors: Mikhail M. Feldstein, Danir F. Bairamov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platé, Gary W. Cleary, Parminder Singh
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Publication number: 20130261526Abstract: Hydrogel compositions are provided (a) that have a continuous hydrophobic phase and a discontinuous hydrophilic phase, (b) that have a discontinuous hydrophilic phase and a continuous hydrophilic phase, or (c) that are entirely composed of a continuous hydrophilic phase. The hydrophobic phase, if present, is composed of a hydrophobic polymer, particularly a hydrophobic pressure-sensitive adhesive (PSA), a plasticizing elastomer, a tackifying resin, and an optional antioxidant. The discontinuous hydrophilic phase, if present, is composed of a crosslinked hydrophilic polymer, particularly a crosslinked cellulosic polymer such as crosslinked sodium carboxymethylcellulose. For those hydrogel compositions containing a continuous hydrophilic phase, the components of the phase include a cellulose ester composition or an acrylate polymer or copolymer, and a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding thereto.Type: ApplicationFiled: May 10, 2013Publication date: October 3, 2013Applicants: CORIUM INTERNATIONAL, INC., A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCESInventors: Gary W. Cleary, Shoreh Parandoosh, Mikhail M. Feldstein, Anatoly E. Chalykh, Nicolai A. Platè, Valery G. Kulichikhin
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Patent number: 8481059Abstract: Hydrogel compositions are provided (a) that have a continuous hydrophobic phase and a discontinuous hydrophilic phase, (b) that have a discontinuous hydrophilic phase and a continuous hydrophilic phase, or (c) that are entirely composed of a continuous hydrophilic phase. The hydrophobic phase, if present, is composed of a hydrophobic polymer, particularly a hydrophobic pressure-sensitive adhesive (PSA), a plasticizing elastomer, a tackifying resin, and an optional antioxidant. The discontinuous hydrophilic phase, if present, is composed of a crosslinked hydrophilic polymer, particularly a crosslinked cellulosic polymer such as crosslinked sodium carboxymethylcellulose. For those hydrogel compositions containing a continuous hydrophilic phase, the components of the phase include a cellulose ester composition or an acrylate polymer or copolymer, and a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding thereto.Type: GrantFiled: June 24, 2009Date of Patent: July 9, 2013Assignees: A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.Inventors: Gary W. Cleary, Shoreh Parandoosh, Mikhail M. Feldstein, Anatoly E. Chalykh, Valery G. Kulichikhin
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Publication number: 20120321569Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition in composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that noncovalently bind to the polar groups on the film-forming polymer, and plasticizer. A method for manufacturing the adhesive composition is provided as well.Type: ApplicationFiled: August 24, 2012Publication date: December 20, 2012Applicants: CORIUM INTERNATIONAL, INC., A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCESInventors: Mikhail M. Feldstein, Danir F. Bairamov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platé, Gary W. Cleary, Parminder Singh
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Patent number: 8273405Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition in composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that noncovalently bind to the polar groups on the film-forming polymer, and plasticizer. A method for manufacturing the adhesive composition is provided as well.Type: GrantFiled: October 7, 2011Date of Patent: September 25, 2012Assignees: A.V. Topcheiv Institute of Petrochemical Synthesis, Russian Academy of Sciences, Corium International, Inc.Inventors: Mikhail M. Feldstein, Danir F. Bairamov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platé, Gary W. Cleary, Parminder Singh
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Publication number: 20120027695Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition in composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that noncovalently bind to the polar groups on the film-forming polymer, and plasticizer. A method for manufacturing the adhesive composition is provided as well.Type: ApplicationFiled: October 7, 2011Publication date: February 2, 2012Applicants: CORIUM INTERNATIONAL, INC., A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCESInventors: MIKHAIL M. FELDSTEIN, Danir F. Bairamov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platé, Gary W. Cleary, Parminder Singh
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Publication number: 20100278757Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition is composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that noncovalently bind to the polar groups on the film-forming polymer, and a plasticizer. A method for manufacturing the adhesive composition is provided as well.Type: ApplicationFiled: July 12, 2010Publication date: November 4, 2010Inventors: Mikhail M. Feldstein, Danir F. Bairamov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platé, Gary W. Cleary, Parminder Singh
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Publication number: 20100239644Abstract: A method of selecting components for use in water-absorbing pressure-sensitive adhesive compositions is provided. The method involves selecting a film-forming polymer, a ladder-like non-covalent crosslinker that is capable of forming a ladder-like interpolymer complex with the film-forming polymer selected, and selecting a carcass-like non-covalent crosslinker that is capable of forming a carcass-like complex with at least one of the film-forming polymer selected or the ladder-like non-covalent crosslinker selected. The adhesive hydrogels provide high adhesion in a swollen state and bridge the gap between conventional pressure sensitive adhesives and bioadhesives. Methods for preparing and using the resulting compositions are also disclosed.Type: ApplicationFiled: April 5, 2010Publication date: September 23, 2010Inventors: Mikhail M. Feldstein, Danir F. Bairamov, Nicolai A. Platé, Valery G. Kulichikhin, Anatoly E. Chalykh, Gary W. Cleary, Parminder Singh