Patents by Inventor Vedamurthy Bhusainahalli Maheshwarappa

Vedamurthy Bhusainahalli Maheshwarappa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanosphere-histone acetyltransferase (HAT) activator composition, process and methods thereof
    Patent number: 9314539
    Abstract: The present invention is in relation to a composition including nanosphere and histone acetyltransferase (HAT) activator. The nanosphere is carbon nanosphere (CSP) which is intrinsically fluorescent and the HAT activator is N-(4-Chloro-3-trifluoromethyl-phenyl)-2-n-propoxy-benzamide. The N-(4-Chloro-3-trifluoromethyl-phenyl)-2-n-propoxy-benzamide is covalently conjugated with the carbon nanosphere. The present invention further relates to a process for obtaining a composition including carbon nanosphere and Histone acetyltransferase (HAT) activator [N-(4-Chloro-3-trifluoromethyl-phenyl)-2-n-propoxy-benzamide]. The composition is capable of crossing blood brain barrier and inducing histone acetylation in brain. Further, the composition is capable of increasing neurogenesis, as well as improving long-term memory formation.
    Type: Grant
    Filed: April 27, 2013
    Date of Patent: April 19, 2016
    Assignees: JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH, UNIVERSITE DE STRASBOURG
    Inventors: Tapas Kumar Kundu, Anne-Laurence Boutillier, Snehajyoti Chatterjee, Muthusamy Eswaramoorthy, Pushpak Mizar, Chantal Mathis, Jean-Christophe Cassel, Romain Neidl, Mohankrishna Dalvoy Vasudevarao, Vedamurthy Bhusainahalli Maheshwarappa
  • NANOSPHERE- HISTONE ACETYLTRANSFERASE (HAT) ACTIVATOR COMPOSITION, PROCESS AND METHODS THEREOF
    Publication number: 20150119466
    Abstract: The present invention is in relation to a composition including nanosphere and histone acetyltransferase (HAT) activator. The nanosphere is carbon nanosphere (CSP) which is intrinsically fluorescent and the HAT activator is N-(4-Chloro-3-trifluoromethyl-phenyl)-2-n-propoxy-benzamide. The N-(4-Chloro-3-trifluoromethyl-phenyl)-2-n-propoxy-benzamide is covalently conjugated with the carbon nanosphere. The present invention further relates to a process for obtaining a composition including carbon nanosphere and Histone acetyltransferase (HAT) activator [N-(4-Chloro-3-trifluoromethyl-phenyl)-2-n-propoxy-benzamide]. The composition is capable of crossing blood brain barrier and inducing histone acetylation in brain. Further, the composition is capable of increasing neurogenesis, as well as improving long-term memory formation.
    Type: Application
    Filed: April 27, 2013
    Publication date: April 30, 2015
    Inventors: Tapas Kumar Kundu, Anne-Laurence Boutillier, Snehajyoti Chatterjee, Muthusamy Eswaramoorthy, Pushpak Mizar, Chantal Mathis, Jean-Christophe Cassel, Romain Neidl, Mohankrishna Dalvoy Vasudevarao, Vedamurthy Bhusainahalli Maheshwarappa