Patents by Inventor Venkata P. Palle

Venkata P. Palle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OXAZOLE AND ISOXAZOLE CRAC MODULATORS
    Publication number: 20160022673
    Abstract: The present invention relates to compounds of Formula (I) along with processes for their preparation that are useful for treating, preventing and/or managing the diseases, disorders, syndromes or conditions associated with the modulation of CRAC. The invention further relates to methods of treating, preventing managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of CRAC of Formula (I).
    Type: Application
    Filed: August 31, 2015
    Publication date: January 28, 2016
    Inventors: Nageswara Rao IRLAPATI, Gokul Keruji DESHMUKH, Vijay Pandurang KARCHE, Santosh Madhukar JACHAK, Neelima SINHA, Venkata P. PALLE, Rajender Kumar KAMBOJ
  • Arylalkylamine compounds as calcium sensing receptor modulators
    Patent number: 9227919
    Abstract: The present invention provides arylalkylamine compounds as calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: January 5, 2016
    Assignee: Lupin Limited
    Inventors: Manojkumar Ramprasad Shukla, Vinod Dinkar Chaudhari, Ankush Gangaram Sarde, Ramesh Dattatraya Phadtare, Mahadeo Bhaskar Tryambake, Dronamraju Prameela, Sanjeev Anant Kulkarni, Rajender Kumar Kamboj, Venkata P. Palle
  • SUBSTITUTED CHROMAN COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS
    Publication number: 20150368222
    Abstract: The present invention provides calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Application
    Filed: September 1, 2015
    Publication date: December 24, 2015
    Inventors: Manojkumar Ramprasad SHUKLA, Ankush Gangaram SARDE, Rajeshkumar Maganlal LORIYA, Vipul Dilip PACHPUTE, Navnath Bajirao WALKE, Talha Hussain KHAN, Sanjeev Anant KULKARNI, Venkata P. PALLE, Rajender Kumar KAMBOJ
  • Pyrrole Derivatives as Alpha 7 NACHR Modulators
    Publication number: 20150361041
    Abstract: Disclosed is a compound of formula (I), wherein R1, R2, R3, R4, R5, R6, R7 and m are as described herein, as a modulator of nicotinic acetylcholine receptors particularly ?7 subtype, its tautomeric forms, its stereoisomers, its pharmaceutically acceptable salts, its pharmaceutical composition, and its combinations with suitable medicaments. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.
    Type: Application
    Filed: January 13, 2014
    Publication date: December 17, 2015
    Applicant: LUPIN LIMITED
    Inventors: Neelima Sinha, Navnath Popat Karche, Anil Kashiram Hajare, Baban Rupaji Thube, Dnyaneshwar Changdeo Bhanage, Venkata P. Palle, Rajender Kumar Kamboj
  • Pyrrole Derivatives as Alpha 7 NACHR Modulators
    Publication number: 20150344422
    Abstract: Disclosed are compounds of the Formula (I), wherein R1, R2, R3, R4, R5, R6, R7 and m are as described herein, as modulators of the nicotinic acetylcholine receptors, particularly the ?7 subtype, their tautomeric forms, stereoisomers, and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, and combinations thereof with suitable other medicaments. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and/or treatment of disorders such as Alzheimer's disease, mild cognitive impairment, and senile dementia.
    Type: Application
    Filed: March 12, 2014
    Publication date: December 3, 2015
    Applicant: Lupin Limited
    Inventors: Neelima Sinha, Navnath Popat Karche, Shridhar Keshav Adurkar, Venkata P. Palle, Rajender Kumar Kamboj
  • Pyrrole derivatives as nicotinic acetylcholine receptor modulators for use in the treatment of neurodegenerative disorders such as alzheimer's and parkinson's disease
    Patent number: 9187420
    Abstract: Disclosed is a compound of formula (I) wherein ‘a’ and R1-R5 are as described herein, as a modulator of nicotinic acetylcholine receptors particularly the ?7 subtype, in a subject in need thereof, as well as analogs, prodrugs, isotopically substituted analogs, metabolites, pharmaceutically acceptable salts, polymorphs, solvates, isomers, clathrates, and co-crystal thereofs, for use either alone or in combinations with suitable other medicaments, and pharmaceutical compositions containing such compounds and analogs. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: November 17, 2015
    Assignee: Lupin Limited
    Inventors: Neelima Sinha, Gourhari Jana, Ajay Ramchandra Tilekar, Navnath Popat Karche, Venkata P. Palle, Rajender Kumar Kamboj
  • Oxazoline and isoxazoline derivatives as CRAC modulators
    Patent number: 9169242
    Abstract: The present invention relates to compounds that are useful for treating, preventing and/or managing the diseases, disorders, syndromes or conditions associated with the modulation of CRAC and to processes for preparing these compounds. The invention further relates to methods of treating, preventing managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of CRAC by these compounds.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: October 27, 2015
    Assignee: LUPIN LIMITED
    Inventors: Nageswara Rao Irlapati, Gokul Keruji Deshmukh, Vijay Pandurang Karche, Santosh Madhukar Jachak, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj
  • Thiazole Derivatives as Alpha 7 NACHR Modulators
    Publication number: 20150299178
    Abstract: Disclosed is a compound of formula (I), wherein R1, R2, R3, R4, R5 and m are as described herein, as a modulator of nicotinic acetylcholine receptors particularly ?7 subtype, its tautomeric forms, its stereoisomers, its pharmaceutically acceptable salts, its pharmaceutical composition, and its combinations with suitable medicaments. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.
    Type: Application
    Filed: November 11, 2013
    Publication date: October 22, 2015
    Applicant: Lupin Limited
    Inventors: Neelima Sinha, Navnath Popat Karche, Anil Kashiram Hajare, Baban Rupaji Thube, Firoj Aftab Raje, Dnyaneshwar Changdeo Bhanage, Sudhakar Maruti Balgude, Venkata P. Palle, Rajender Kumar Kamboj
  • HETEROCYCLYL COMPOUNDS
    Publication number: 20150299186
    Abstract: The present invention is related to heteroaryl compounds as MEK inhibitors. The invention includes heteroaryl compounds of formula I, their tautomers and pharmaceutically acceptable salts, combinations with suitable medicament and pharmaceutical compositions thereof. The present invention also includes process of preparation of the said compounds and intended use in therapy of them.
    Type: Application
    Filed: March 11, 2013
    Publication date: October 22, 2015
    Applicant: LUPIN LIMITED
    Inventors: Bhavesh DAVE, Rakesh Kumar BANERJEE, Samiron PHUKAN, Abhijit Datta KHOJE, Rajkumar HANGARGE, Jitendra Sambhaji JADHAV, Venkata P. PALLE, Rajender Kumar KAMBOJ
  • Substituted chroman compounds as calcium sensing receptor modulators
    Patent number: 9163001
    Abstract: The present invention provides calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: October 20, 2015
    Assignee: LUPIN LIMITED
    Inventors: Manojkumar Ramprasad Shukla, Ankush Gangaram Sarde, Rajeshkumar Maganlal Loriya, Vipul Dilip Pachpute, Navnath Bajirao Walke, Talha Hussain Khan, Sanjeev Anant Kulkarni, Venkata P. Palle, Rajender Kumar Kamboj
  • Thiazole Derivatives as Alpha 7 nAChR Modulators
    Publication number: 20150291617
    Abstract: Disclosed is a compound of formula (I) wherein Y, Ring D, m and R1-R4 are as described herein, as a modulator of nicotinic acetylcholine receptors particularly the ?7 subtype, in a subject in need thereof, as well as pharmaceutically acceptable salts, polymorphs, solvates, and isomers thereofs, for use either alone or in combinations with suitable other medicaments, and pharmaceutical compositions containing such compounds. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.
    Type: Application
    Filed: February 22, 2013
    Publication date: October 15, 2015
    Applicant: LUPIN LIMITED
    Inventors: Neelima Sinha, Navnath Popat Karche, Anil Kashiram Hajare, Shridhar Keshav Adurkar, Bikramjit Singh Lairikyengbam, Firoj Aftab Raje, Ajay Ramchandra Tilekar, Baban Rupaji Thube, Venkata P. Palle, Rajender Kumar Kamboj
  • ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS
    Publication number: 20150239827
    Abstract: The present invention provides arylalkylamine compounds as calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Application
    Filed: August 23, 2013
    Publication date: August 27, 2015
    Inventors: Manojkumar Ramprasad Shukla, Vinod Dinkar Chaudhari, Ankush Gangaram Sarde, Ramesh Dattatraya Phadtare, Mahadeo Bhaskar Tryambake, Dronamraju Prameela, Sanjeev Anant Kulkarni, Rajender Kumar Kamboj, Venkata P. Palle
  • Heteroaryl Derivatives as Alpha7 NACHR Modulators
    Publication number: 20150231143
    Abstract: Disclosed is a compound of formula I: wherein Z, m and R1-R6 are as described herein, as a modulator of nicotinic acetylcholine receptors particularly the ?7 subtype, in a subject in need thereof, as well as analogues, prodrugs, isotopically substituted analogs, metabolites, pharmaceutically acceptable salts, polymorphs, solvates, isomers, clathrates, and co-crystal thereofs, for use either alone or in combinations with suitable other medicaments, and pharmaceutical compositions containing such compounds and analogues. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.
    Type: Application
    Filed: May 6, 2015
    Publication date: August 20, 2015
    Applicant: Lupin Limited
    Inventors: Neelima Sinha, Gourhari Jana, Sachchidanand Sachchidanand, Sanjay Pralhad Kurhade, Navnath Popat Karche, Anil Kashiram Hajare, Ajay Ramchandra Tilekar, Venkata P. Palle, Rajender Kumar Kamboj
  • Heteroaryl derivatives as alpha7 nAChR modulators
    Patent number: 9072731
    Abstract: Disclosed is a compound of formula (I), wherein Z, m and R1-R6 are as described herein, as a modulator of nicotinic acetylcholine receptors particularly the ?7 subtype, in a subject in need thereof, as well as analogs, prodrugs, isotopically substituted analogs, metabolites, pharmaceutically acceptable salts, polymorphs, solvates, isomers, clathrates, and co-crystal thereof, for use either alone or in combinations with suitable other medicaments, and pharmaceutical compositions containing such compounds and analogs. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: July 7, 2015
    Assignee: Lupin Limited
    Inventors: Neelima Sinha, Gourhari Jana, Sachchidanand Sachchidanand, Sanjay Pralhad Kurhade, Navnath Popat Karche, Anil Kashiram Hajare, Ajay Ramchandra Tilekar, Venkata P. Palle, Rajender Kumar Kamboj
  • Antiviral compounds with a heterotricycle moiety
    Patent number: 9073942
    Abstract: Disclosed are compounds of formula (I) for use as antiviral agents, particularly as anti-hepatitis virus C agents, wherein A, B, U, R1-R7, m, n, and q are as described herein. Also disclosed are pharmaceutical compositions and methods of treating or preventing viral infection in a host by the use of these compounds, either alone or in combination with other pharmaceutically active agents. Further disclosed are methods of preparing such compounds.
    Type: Grant
    Filed: February 9, 2013
    Date of Patent: July 7, 2015
    Assignee: Lupin Limited
    Inventors: Vidya Ramdas, Advait Arun Joshi, Moloy Manoj Banerjee, Amit Kumar Das, Deepak Sahebrao Walke, Venkata P. Palle, Rajender Kumar Kamboj
  • Antiviral compounds with a dibenzooxaheterocycle moiety
    Patent number: 9073943
    Abstract: Disclosed are compounds of formula (I) for use as antiviral agents, particularly as anti-hepatitis virus C agents, wherein R-R 6 and q are as described herein. Also disclosed are pharmaceutical compositions and methods of treating or preventing viral infection in a host by the use of these compounds, either alone or in combination with other pharmaceutically active agents. Further disclosed are methods of preparing such compounds. (I).
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: July 7, 2015
    Assignee: Lupin Limited
    Inventors: Vidya Ramdas, Advait Arun Joshi, Moloy Manoj Banerjee, Amit Kumar Das, Deepak Sahebrao Walke, Venkata P. Palle, Rajender Kumar Kamboj
  • Tetrahydroquinazolinone Derivatives as PARP Inhibitors
    Publication number: 20150152118
    Abstract: Disclosed are compounds of formula (I), their tautomeric forms, stereoisomers, and pharmaceutically acceptable salts thereof, wherein R1-R6, R7a-d, R8a-d, A, M, n, and p are as defined in the specification, pharmaceutical compositions including a compound, tautomer, stereoisomer, or salt thereof, and methods of treating or preventing diseases or disorders, for example, cancer, that are amenable to treatment or prevention by inhibiting the PARP enzyme of a subject.
    Type: Application
    Filed: July 9, 2013
    Publication date: June 4, 2015
    Applicant: LUPIN LIMITED
    Inventors: Gourhari Jana, Sanjay Pralhad Kurhade, Arun Rangnath Jagdale, Gagan Kukreja, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj
  • N-pyrazole Areceptor agonists
    Patent number: 9045519
    Abstract: The present disclosure provides a process for the preparation of 2-adenosine N-pyrazole compounds exemplified by the structure shown below that are potent and selective agonists for A2A adenosine receptor, compositions comprising these compounds, and methods for using these compound to stimulate mammalian coronary vasodilatation for imaging the heart.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: June 2, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Jeff A. Zablocki, Elfatih O. Elzein, Venkata P. Palle, Luiz Belardinelli
  • HETEROCYCLYL COMPOUNDS AS MEK INHIBITORS
    Publication number: 20150133424
    Abstract: The present disclosure is related to heteroaryl compounds as MEK inhibitors. These compounds include heteroaryl compounds of formula I, their pharmaceutically acceptable salts, combinations with suitable medicament and pharmaceutical compositions thereof. The present disclosure also includes processes of preparation of the compounds and their use in methods of treatment.
    Type: Application
    Filed: March 11, 2013
    Publication date: May 14, 2015
    Inventors: Bhavesh Dave, Rakesh Kumar Banerjee, Samiron Phukan, Abhijit Datta Khoje, Rajkumar Hangarge, Jitendra Sambhaji Jadhav, Venkata P. Palle, Rajender Kumar Kamboj
  • SUBSTITUTED PYRIDINE COMPOUNDS AS CRAC MODULATORS
    Publication number: 20150111900
    Abstract: The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release-activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.
    Type: Application
    Filed: May 1, 2013
    Publication date: April 23, 2015
    Inventors: Nageswara Rao Irlapati, Zubair Abdul Wajid Shaikh, Vijay Pandurang Karche, Gokul Keruji Deshmukh, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj