Patents by Inventor Venkatasamy Manivel

Venkatasamy Manivel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7335686
    Abstract: This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention also provides methods of using the novel class of acidic amino acid/dicarboxylic acid derivatives of the general formula ZOC—(CRR)m—COOH, wherein: m=2, 3 or 4; Z is OH or NH2; one R in the compound is from the group consisting of SO3H, OSO3H, CH2—SO3H, CH2—OSO3H, and NHSO3H, and the remaining Rs are H or NH2, for inhibition of osteoclastogenesis.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: February 26, 2008
    Assignee: Council of Scientific and Industrial Research
    Inventors: Kanury Venkata Subba Rao, Mohan Ramachandran Wani, Venkatasamy Manivel, Parameswaran Perunninakulath Subrayan, Vinod Kumar Singh, Ramasamy Vijaya Anand, Ehrlich Desa, Gyan Chandra Mishra, Anil Chatterji
  • Publication number: 20050171063
    Abstract: The invention provides the use of phosphono derivatives of selected aliphatic acids represented by the structural formulae R—COOH, R being PO3H2 or CR1R2—PO3H2 where R1/R2 are H, OH, COOH or alkyl groups for the treatment of malaria. The use of the compound comprises administering an effective amount of said compounds for in vitro and in vivo studies using malarial parasites (Plasmodium falciparum and Plasmodium berghei).
    Type: Application
    Filed: July 16, 2004
    Publication date: August 4, 2005
    Inventors: Pawan Malhotra, Palakodeti Dasaradhi, Asif Mohammed, Manzar Hossain, Sunil Mukherji, Venkatasamy Manivel, Kanury Subba Rao, Parameswaran Subrayan, Anil Chatterji
  • Publication number: 20050085547
    Abstract: The present invention is related to compounds having general formula Z-OC(CRn1Rn2)—CO-Z wherein Z=OH or NH2 and n1=n2=1 to 8, for modulation of immune response by differentiation dendritic cells consisting novel class of amino acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids, and their amides) of the general formula ZOC—CR3R4—CR2(NHR1)—COOH, ZOC—CR5R6—CR3R4—C(NHR2)—COOH, ZOC—CR7R8—CR5R6—CR3R4—CR1(NHR2)—COOH wherein Z=OH or NH2; R1 to R8 denotes H, SO3H, or OSO3H. In addition, the dicarboxylic acids and their amides ZOC—(CH2)n—CR1R2—COOH, where Z=OH or NH2; and n=1, 2, 3. The groups R1/R2=H/SO3H or OSO3H or CH2—SO3H or CH2—OSO3H and vice versa. The factors also contain different divalent metal cations such as Mg, Ca and Zn.
    Type: Application
    Filed: December 31, 2003
    Publication date: April 21, 2005
    Applicant: Council of Scientific & Industrial Research
    Inventors: Anil Chatterji, Krishnamurthy Natarajan, Venkatasamy Manivel, Kanury Subba Rao, Parameswaran Subrayan, Vinod Singh, Ramasamy Anand, Ehrlich Desa
  • Publication number: 20050085537
    Abstract: This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention also provides methods of using the novel class of acidic amino acid/dicarboxylic acid derivatives of the general formula ZOC—(CRR)m—COOH, wherein: m=2, 3 or 4; Z is OH or NH2; one R in the compound is from the group consisting of SO3H, OSO3H, CH2—SO3H, CH2—OSO3H, and NHSO3H, and the remaining Rs are H or NH2, for inhibition of osteoclastogenesis.
    Type: Application
    Filed: December 30, 2003
    Publication date: April 21, 2005
    Applicant: Council of Scientific & Industrial Research
    Inventors: Kanury Rao, Mohan Wani, Venkatasamy Manivel, Parameswaran Subrayan, Vinod Singh, Ramasamy Anand, Ehrlich Desa, Gyan Mishra, Anil Chatterji
  • Publication number: 20050085546
    Abstract: The present invention is related to compounds having general formula Z-OC (CRn1Rn2)—CO-Z wherein Z=OH or NH2 and n1=n2=1 to 8, useful for modulation of immune response by inducing differentiation of dendritic cells consisting novel class of amino acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids, and their amides) of the general formula ZOC—CR3R4—CR2(NHR1)—COOH, ZOC—CR5R6—CR3R4—CR1(NHR2)—COOH, ZOC—CR7R8—CR5R6—CR3R4—CR1N2)—COOH wherein Z=OH or NH2; R1 to R8 denotes H, SO3H, or OSO3H. In addition, the dicarboxylic acids and their amides ZOC—(CH2)n—CR1R2—COOH, where Z=OH or NH2; and n=1, 2, 3. The groups R1/R2=H/SO3H or OSO3H or CH2—SO3H or CH2—OSO3H and vice versa. The factors also contain different divalent metal cations such as Mg, Ca and Zn.
    Type: Application
    Filed: December 31, 2003
    Publication date: April 21, 2005
    Applicant: Council of Scientific & Industrial Research
    Inventors: Anil Chatterji, Krishnamurthy Natarajan, Venkatasamy Manivel, Kanury Venkata Subba Rao, Parameswaran Subrayan, Vinod Singh, Ramasamy Anand, Ehrlich Desa